期刊
MOLECULES
卷 24, 期 22, 页码 -出版社
MDPI
DOI: 10.3390/molecules24224024
关键词
bioavailability; enterohepatic; flavonoid; phase 2 metabolism
Research on the bioavailability of anthocyanins has focused, historically, on the non-flavonoid (C-6-C-n) products that arise from anthocyanins in vivo. However, this review focuses on the products of anthocyanins that still possess the flavonoid structure (C-6-C-3-C-6). Described herein are aspects of the in vivo pool of C-6-C-3-C-6 anthocyanin-derived intermediates. Properties related to molecular size, shape, and polarity conveyed by six major anthocyanidin structures are discussed. The presence of a glycoside or not, and a variety of possible phase 2 conjugates, gives rise to a chemically diverse pool of C-6-C-3-C-6 intermediates. Chemical properties influence the in vivo stability of anthocyanin-derived products, as well as their suitability as a substrate for xenobiotic conjugation and transport, and their association with the biomatrix. The flavonoid structure is associated with bioactivity and the particular properties of these C-6-C-3-C-6 products of anthocyanins determines their deposition in the body, which may influence in vivo processes and ultimately health outcomes.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据