Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity

Ki-67 protein as a tumour proliferation marker

(2019) Sunil Sankunny Menon et al.   CLINICA CHIMICA ACTA

Investigating the properties of TBA variants with twin thrombin binding domains

(2019) Teresa Amato et al.   Scientific Reports

Multi-targeted effects of G4-aptamers and their antiproliferative activity against cancer cells

(2018) Anna M. Ogloblina et al.   BIOCHIMIE

The “Janus face” of the thrombin binding aptamer: Investigating the anticoagulant and antiproliferative properties through straightforward chemical modifications

(2018) Veronica Esposito et al.   BIOORGANIC CHEMISTRY

Ki-67: more than a proliferation marker

(2018) Xiaoming Sun et al.   CHROMOSOMA

Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative

(2018) Weronika Kotkowiak et al.   Molecular Therapy-Nucleic Acids

The roles of signal transducer and activator of transcription factor 3 in tumor angiogenesis

(2017) Peng Gao et al.   Oncotarget

The Evaluation of Pharmacodynamics and Pharmacokinetics of Anti-thrombin DNA Aptamer RA-36

(2017) Elena Zavyalova et al.   Frontiers in Pharmacology

Origin of the U87MG glioma cell line: Good news and bad news

(2016) Marie Allen et al.   Science Translational Medicine

Cation Coordination Alters the Conformation of a Thrombin-Binding G-Quadruplex DNA Aptamer That Affects Inhibition of Thrombin

(2016) Elena Zavyalova et al.   Nucleic Acid Therapeutics

Anti-proliferative and pro-apoptotic effects of GHRH antagonists in prostate cancer

(2016) Laura Muñoz-Moreno et al.   Oncotarget

Study of the Function of G-Rich Aptamers Selected for Lung Adenocarcinoma

(2015) Jun Hu et al.   Chemistry-An Asian Journal

Site specific replacements of a single loop nucleoside with a dibenzyl linker may switch the activity of TBA from anticoagulant to antiproliferative

(2015) Maria Scuotto et al.   NUCLEIC ACIDS RESEARCH

Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides

(2015) Nan Zhang et al.   Chemical Science

How to Train Your Dragon: Targeted Delivery of MicroRNA to Cancer Cells In Vivo

(2014) Marcin Kortylewski et al.   MOLECULAR THERAPY

G-triplex structure and formation propensity

(2014) Linda Cerofolini et al.   NUCLEIC ACIDS RESEARCH

Module-Activity Relationship of G-quadruplex Based DNA Aptamers for Human Thrombin

(2013) E. Zavyalova et al.   CURRENT MEDICINAL CHEMISTRY

A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinoma

(2013) Jonathan E. Rosenberg et al.   INVESTIGATIONAL NEW DRUGS

General Cell-Binding Activity of Intramolecular G-Quadruplexes with Parallel Structure

(2013) Tianjun Chang et al.   PLoS One

High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

(2012) Irene Russo Krauss et al.   NUCLEIC ACIDS RESEARCH

DNA-binding and regulatory properties of the transcription factor and putative tumor suppressor p150Sal2

(2011) Hongcang Gu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process

(2011) Roman V. Reshetnikov et al.   NUCLEIC ACIDS RESEARCH

Screening and Improvement of an Anti-VEGF DNA Aptamer

(2010) Yoshihiko Nonaka et al.   MOLECULES

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

(2009) Paula J. Bates et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Cation localization and movement within DNA thrombin binding aptamer in solution

(2009) Marko Trajkovski et al.   ORGANIC & BIOMOLECULAR CHEMISTRY