The autoantibody-mediated encephalitides: from clinical observations to molecular pathogenesis

NMDA receptor dysfunction via unmutated human antibodies against the NR1 subunit

(2019) Nina Kerstin Wenke et al.   ANNALS OF NEUROLOGY

Development of the clinical assessment scale in autoimmune encephalitis

(2019) Jung-Ah Lim et al.   ANNALS OF NEUROLOGY

001 Altered interval timing as a novel marker of cognitive fluctuations in lewy body dementia

(2019) Elie Matar et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Refining the psychiatric syndrome of anti-N -methyl-d -aspartate receptor encephalitis

(2018) N. Warren et al.   ACTA PSYCHIATRICA SCANDINAVICA

Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis

(2018) Stefanie H. Mueller et al.   ANNALS OF NEUROLOGY

N-methyl-D-aspartate receptor antibody production from germinal center reactions: Therapeutic implications

(2018) Mateusz Makuch et al.   ANNALS OF NEUROLOGY

Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis

(2018) Divyanshu Dubey et al.   ANNALS OF NEUROLOGY

Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica

(2018) Robert Wilson et al.   BRAIN

Distinct HLA associations of LGI1 and CASPR2-antibody diseases

(2018) Sophie Binks et al.   BRAIN

The Movement disorder associated with NMDAR antibody-encephalitis is complex and characteristic: an expert video-rating study

(2018) James A Varley et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Antibody-Mediated Encephalitis

(2018) Josep Dalmau et al.   NEW ENGLAND JOURNAL OF MEDICINE

NMDA Receptor Autoantibodies in Autoimmune Encephalitis Cause a Subunit-Specific Nanoscale Redistribution of NMDA Receptors

(2018) Laurent Ladépêche et al.   Cell Reports

LGI1 and CASPR2 neurological autoimmunity in children

(2018) A. Sebastian López-Chiriboga et al.   ANNALS OF NEUROLOGY

Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis

(2018) Thaís Armangue et al.   LANCET NEUROLOGY

The clinical features, underlying immunology, and treatment of autoantibody-mediated movement disorders

(2018) Valentina Damato et al.   MOVEMENT DISORDERS

Glutamate receptor δ2 serum antibodies in pediatric opsoclonus myoclonus ataxia syndrome

(2018) Georgina Berridge et al.   NEUROLOGY

Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction

(2018) Holger Haselmann et al.   NEURON

The Psychiatric Phenotype of Anti-NMDA Receptor Encephalitis

(2018) Lucy L. Gibson et al.   JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES

A score that predicts 1-year functional status in patients with anti-NMDA receptor encephalitis

(2018) Ramani Balu et al.   NEUROLOGY

EEG findings in NMDA encephalitis – A systematic review

(2018) Lisa Gillinder et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Psychosis: an autoimmune disease?

(2017) Adam A. J. Al-Diwani et al.   IMMUNOLOGY

LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes

(2017) Sophie N M Binks et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Intracellular and non-neuronal targets of voltage-gated potassium channel complex antibodies

(2017) Bethan Lang et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Clinical manifestations of the anti-IgLON5 disease

(2017) Carles Gaig et al.   NEUROLOGY

LGI1-antibody encephalitis is characterised by frequent, multifocal clinical and subclinical seizures

(2017) Sidra Aurangzeb et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients

(2017) Julie Jézéquel et al.   Nature Communications

Neuropathological criteria of anti-IgLON5-related tauopathy

(2016) Ellen Gelpi et al.   ACTA NEUROPATHOLOGICA

Ephrin-B2 prevents N-methyl-D-aspartate receptor antibody effects on memory and neuroplasticity

(2016) Jesús Planagumà et al.   ANNALS OF NEUROLOGY

From VGKC to LGI1 and Caspr2 encephalitis: The evolution of a disease entity over time

(2016) A. van Sonderen et al.   AUTOIMMUNITY REVIEWS

Motor cortex and hippocampus are the two main cortical targets in LGI1-antibody encephalitis

(2016) Vincent Navarro et al.   BRAIN

Human cerebrospinal fluid monoclonalN-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis

(2016) Jakob Kreye et al.   BRAIN

Diagnostic and therapeutic strategies for management of autoimmune encephalopathies

(2016) Divyanshu Dubey et al.   Expert Review of Neurotherapeutics

Multicentre comparison of a diagnostic assay: aquaporin-4 antibodies in neuromyelitis optica

(2016) Patrick Waters et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A clinical approach to diagnosis of autoimmune encephalitis

(2016) Francesc Graus et al.   LANCET NEUROLOGY

Rituximab treatment for autoimmune limbic encephalitis in an institutional cohort

(2016) Woo-Jin Lee et al.   NEUROLOGY

Human neurexin-3α antibodies associate with encephalitis and alter synapse development

(2016) Nuria Gresa-Arribas et al.   NEUROLOGY

Anti-LGI1 encephalitis

(2016) Agnes van Sonderen et al.   NEUROLOGY

The relevance of VGKC positivity in the absence of LGI1 and Caspr2 antibodies

(2016) Agnes van Sonderen et al.   NEUROLOGY

Tocilizumab in Autoimmune Encephalitis Refractory to Rituximab: An Institutional Cohort Study

(2016) Woo-Jin Lee et al.   Neurotherapeutics

Antibody-associated epilepsies: Clinical features, evidence for immunotherapies and future research questions

(2016) Ochuko D. Bakpa et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Diagnostic and therapeutic strategies for management of autoimmune encephalopathies

(2016) Divyanshu Dubey et al.   Expert Review of Neurotherapeutics

Bortezomib Treatment for Patients With Anti-N-Methyl-d-Aspartate Receptor Encephalitis

(2016) Volker Behrendt et al.   JAMA Neurology

Dopamine-2 receptor extracellular N-terminus regulates receptor surface availability and is the target of human pathogenic antibodies from children with movement and psychiatric disorders

(2016) Nese Sinmaz et al.   Acta Neuropathologica Communications

Autoimmune Encephalitis in Postpartum Psychosis

(2015) Veerle Bergink et al.   AMERICAN JOURNAL OF PSYCHIATRY

Immune therapy in autoimmune encephalitis: a systematic review

(2015) Margherita Nosadini et al.   Expert Review of Neurotherapeutics

Anti-DPPX encephalitis

(2015) Johannes Piepgras et al.   NEUROLOGY

Antibodies to GABAA receptor  1 and  2 subunits: Clinical and serologic characterization

(2015) P. Pettingill et al.   NEUROLOGY

When a serum test overrides the clinical assessment

(2015) T. Armangue et al.   NEUROLOGY

Immune therapy in autoimmune encephalitis: a systematic review

(2015) Margherita Nosadini et al.   Expert Review of Neurotherapeutics

Cell-surface central nervous system autoantibodies: Clinical relevance and emerging paradigms

(2014) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

Seroprevalence of autoantibodies against brain antigens in health and disease

(2014) Liane Dahm et al.   ANNALS OF NEUROLOGY

Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes

(2014) Alexander Carvajal-González et al.   BRAIN

Human N-methyl D-aspartate receptor antibodies alter memory and behaviour in mice

(2014) Jesús Planagumà et al.   BRAIN

Clinical and experimental studies of potentially pathogenic brain-directed autoantibodies: current knowledge and future directions

(2014) James Varley et al.   JOURNAL OF NEUROLOGY

Limbic encephalitis due to GABABand AMPA receptor antibodies: a case series

(2014) M Dogan Onugoren et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Identification and Characterization of GABAA Receptor Autoantibodies in Autoimmune Encephalitis

(2014) T. Ohkawa et al.   JOURNAL OF NEUROSCIENCE

Encephalitis with refractory seizures, status epilepticus, and antibodies to the GABAA receptor: a case series, characterisation of the antigen, and analysis of the effects of antibodies

(2014) Mar Petit-Pedrol et al.   LANCET NEUROLOGY

A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study

(2014) Lidia Sabater et al.   LANCET NEUROLOGY

Movement disorders in children with anti-NMDAR encephalitis and other autoimmune encephalopathies

(2014) Shekeeb S. Mohammad et al.   MOVEMENT DISORDERS

DPPX potassium channel antibody: Frequency, clinical accompaniments, and outcomes in 20 patients

(2014) W. O. Tobin et al.   NEUROLOGY

Effect of Rituximab in Patients With Leucine-Rich, Glioma-Inactivated 1 Antibody–Associated Encephalopathy

(2014) Sarosh R. Irani et al.   JAMA Neurology

Episodic Bradycardia as Neurocardiac Prodrome to Voltage-Gated Potassium Channel Complex/Leucine-Rich, Glioma Inactivated 1 Antibody Encephalitis

(2014) Georges Naasan et al.   JAMA Neurology

Abnormal Neurons in Teratomas in NMDAR Encephalitis

(2014) Gregory S. Day et al.   JAMA Neurology

A novel treatment-responsive encephalitis with frequent opsoclonus and teratoma

(2013) Thaís Armangue et al.   ANNALS OF NEUROLOGY

Herpes simplex virus encephalitis is a trigger of brain autoimmunity

(2013) Thaís Armangue et al.   ANNALS OF NEUROLOGY

Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype

(2013) Sarosh R. Irani et al.   BRAIN

Autoimmune encephalitis: Recent updates and emerging challenges

(2013) Sudarshini Ramanathan et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study

(2013) Maarten J Titulaer et al.   LANCET NEUROLOGY

N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse

(2013) Yael Hacohen et al.   MOVEMENT DISORDERS

The spectrum of movement disorders in children with anti-NMDA receptor encephalitis

(2013) José Fidel Baizabal-Carvallo et al.   MOVEMENT DISORDERS

Herpes simplex encephalitis relapse with chorea is associated with autoantibodies toN-Methyl-D-aspartate receptor or dopamine-2 receptor

(2013) Shekeeb S. Mohammad et al.   MOVEMENT DISORDERS

Frequency and Characteristics of Isolated Psychiatric Episodes in Anti–N-Methyl-d-Aspartate Receptor Encephalitis

(2013) Matthew S. Kayser et al.   JAMA Neurology

Determination of Neuronal Antibodies in Suspected and Definite Creutzfeldt-Jakob Disease

(2013) Oriol Grau-Rivera et al.   JAMA Neurology

Encephalitis and antibodies to dipeptidyl-peptidase-like protein-6, a subunit of Kv4.2 potassium channels

(2012) Anna Boronat et al.   ANNALS OF NEUROLOGY

Morvan syndrome: Clinical and serological observations in 29 cases

(2012) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis

(2012) Harald Prüss et al.   ANNALS OF NEUROLOGY

What should you know about limbic encephalitis?

(2012) Sara Machado et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis

(2012) C. G. Bien et al.   BRAIN

Antibodies to surface dopamine-2 receptor in autoimmune movement and psychiatric disorders

(2012) Russell C. Dale et al.   BRAIN

Disrupted surface cross-talk between NMDA and Ephrin-B2 receptors in anti-NMDA encephalitis

(2012) Lenka Mikasova et al.   BRAIN

The Frequency of Autoimmune N-Methyl-D-Aspartate Receptor Encephalitis Surpasses That of Individual Viral Etiologies in Young Individuals Enrolled in the California Encephalitis Project

(2012) M. S. Gable et al.   CLINICAL INFECTIOUS DISEASES

Ovarian Teratoma Associated With Anti-N-Methyl D-Aspartate Receptor Encephalitis

(2012) Marcus Dabner et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Anti-NMDA Receptor Encephalitis Antibody Binding Is Dependent on Amino Acid Identity of a Small Region within the GluN1 Amino Terminal Domain

(2012) A. J. Gleichman et al.   JOURNAL OF NEUROSCIENCE

Neuronal autoantigens—pathogenesis, associated disorders and antibody testing

(2012) Eric Lancaster et al.   Nature Reviews Neurology

Insights From LGI1 and CASPR2 Potassium Channel Complex Autoantibody Subtyping

(2012) Christopher J. Klein et al.   JAMA Neurology

Glycine Receptor Autoimmune Spectrum With Stiff-Man Syndrome Phenotype

(2012) Andrew McKeon et al.   JAMA Neurology

Autoimmune epilepsies

(2011) Sarosh R Irani et al.   CURRENT OPINION IN NEUROLOGY

Potentially pathogenic autoantibodies associated with epilepsy and encephalitis in children and adults

(2011) Angela Vincent et al.   EPILEPSIA

GABAB receptor antibodies in limbic encephalitis and anti-GAD-associated neurologic disorders

(2011) A. Boronat et al.   NEUROLOGY

Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome

(2011) E. Lancaster et al.   NEUROLOGY

Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis

(2010) Sarosh R. Irani et al.   ANNALS OF NEUROLOGY

N-methyl-d-aspartate antibody encephalitis: temporal progression of clinical and paraclinical observations in a predominantly non-paraneoplastic disorder of both sexes

(2010) Sarosh R. Irani et al.   BRAIN

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan’s syndrome and acquired neuromyotonia

(2010) Sarosh R. Irani et al.   BRAIN

Antiglycine-receptor encephalomyelitis with rigidity

(2010) N. Mas et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cellular and Synaptic Mechanisms of Anti-NMDA Receptor Encephalitis

(2010) E. G. Hughes et al.   JOURNAL OF NEUROSCIENCE

Anti-N-methyl-D-Aspartate-Receptor Encephalitis in a Four-Year-Old Girl

(2010) Roberta Biancheri et al.   JOURNAL OF PEDIATRICS

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

(2010) Meizan Lai et al.   LANCET NEUROLOGY

Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis

(2010) Josep Dalmau et al.   LANCET NEUROLOGY

Metabotropic glutamate receptors: From the workbench to the bedside

(2010) F. Nicoletti et al.   NEUROPHARMACOLOGY

N-methyl-D-aspartate receptor antibodies in pediatric dyskinetic encephalitis lethargica

(2009) Russell C. Dale et al.   ANNALS OF NEUROLOGY

AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location

(2009) Meizan Lai et al.   ANNALS OF NEUROLOGY

Nationwide Survey of Acute Juvenile Female Non-Herpetic Encephalitis in Japan: Relationship to Anti-N-Methyl-D-Aspartate Receptor Encephalitis

(2009) Satoshi Kamei et al.   INTERNAL MEDICINE

Antibodies to the GABAB receptor in limbic encephalitis with seizures: case series and characterisation of the antigen

(2009) Eric Lancaster et al.   LANCET NEUROLOGY

Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies

(2008) Josep Dalmau et al.   LANCET NEUROLOGY

PROGRESSIVE ENCEPHALOMYELITIS, RIGIDITY, AND MYOCLONUS: A NOVEL GLYCINE RECEPTOR ANTIBODY

(2008) M. Hutchinson et al.   NEUROLOGY