From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective

标题
From bosentan (Tracleer®) to macitentan (Opsumit®): The medicinal chemistry perspective
作者
关键词
G-protein-coupled receptor (GPCR), Endothelin, Endothelin receptor antagonists (ERA), Macitentan, Pulmonary arterial hypertension (PAH), Sulfamide, Pyrimidine
出版物
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Volume 26, Issue 15, Pages 3381-3394
出版商
Elsevier BV
发表日期
2016-06-12
DOI
10.1016/j.bmcl.2016.06.014

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