Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes
出版年份 2019 全文链接
标题
Down‐regulation of MTHFD2 inhibits NSCLC progression by suppressing cycle‐related genes
作者
关键词
-
出版物
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-11-28
DOI
10.1111/jcmm.14844
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC
- (2019) D. Ross Camidge et al. Nature Reviews Clinical Oncology
- Immunotherapy in Non-Small Cell Lung Cancer: Facts and Hopes
- (2019) Deborah B Doroshow et al. CLINICAL CANCER RESEARCH
- On-target resistance to the mutant-selective EGFR inhibitor osimertinib can develop in an allele specific manner dependent on the original EGFR activating mutation
- (2019) Benjamin P Brown et al. CLINICAL CANCER RESEARCH
- De novo synthesis of serine and glycine fuels purine nucleotide biosynthesis in human lung cancer tissues
- (2019) Teresa W. M. Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MTHFD2 links RNA methylation to metabolic reprogramming in renal cell carcinoma
- (2019) Nathanael H. Green et al. ONCOGENE
- EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis
- (2018) Nirmalya Sen et al. MOLECULAR CARCINOGENESIS
- Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells
- (2018) Juliane Hitzel et al. Nature Communications
- OUP accepted manuscript
- (2018) JNCI-Journal of the National Cancer Institute
- Mitochondrial translation requires folate-dependent tRNA methylation
- (2018) Raphael J. Morscher et al. NATURE
- Histidine-Dependent Protein Methylation Is Required for Compartmentalization of CTP Synthase
- (2018) Wei-Cheng Lin et al. Cell Reports
- Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2
- (2018) Tatsunori Nishimura et al. ONCOGENE
- Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes
- (2018) Gholamreza Bidkhori et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Lung cancer: current therapies and new targeted treatments
- (2017) Fred R Hirsch et al. LANCET
- The natural product carolacton inhibits folate-dependent C1 metabolism by targeting FolD/MTHFD
- (2017) Chengzhang Fu et al. Nature Communications
- Crystal Structure of the Emerging Cancer Target MTHFD2 in Complex with a Substrate-Based Inhibitor
- (2016) Robert Gustafsson et al. CANCER RESEARCH
- Targeting MTHFD2 in acute myeloid leukemia
- (2016) Yana Pikman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle
- (2016) I. Ben-Sahra et al. SCIENCE
- Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism
- (2016) Chengguang Zhao et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- SNAI2/SLUG and estrogen receptor mRNA expression are inversely correlated and prognostic of patient outcome in metastatic non-small cell lung cancer
- (2015) Akin Atmaca et al. BMC CANCER
- Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development
- (2015) P. M. Tedeschi et al. MOLECULAR CANCER RESEARCH
- KRAS Mutation Status Is Associated with Enhanced Dependency on Folate Metabolism Pathways in Non-Small Cell Lung Cancer Cells
- (2014) D. M. Moran et al. MOLECULAR CANCER THERAPEUTICS
- Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
- (2014) Roland Nilsson et al. Nature Communications
- MicroRNA-9 Inhibition of Cell Proliferation and Identification of Novel miR-9 Targets by Transcriptome Profiling in Breast Cancer Cells
- (2012) S. Duygu Selcuklu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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