Rho‐kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction

Stable but Progressive Nature of Heart Failure: Considerations for Primary Care Physicians

(2018) Inder Anand   American Journal of Cardiovascular Drugs

Rho kinase activation in circulating leukocytes is related to hypertensive myocardial remodeling

(2018) Maria P. Ocaranza et al.   CLINICAL SCIENCE

Inhibition of Rho-kinase Attenuates Left Ventricular Remodeling Caused by Chronic Intermittent Hypoxia in Rats via Suppressing Myocardial Inflammation and Apoptosis

(2017) Zhi-hua Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Impact of granulocyte contamination on PBMC integrity of shipped blood samples: Implications for multi-center studies monitoring regulatory T cells

(2017) Charuta Agashe et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Targeting the RhoA-ROCK pathway to reverse T-cell dysfunction in SLE

(2016) Cristina Rozo et al.   ANNALS OF THE RHEUMATIC DISEASES

Rho Kinases and Cardiac Remodeling

(2016) Toru Shimizu et al.   CIRCULATION JOURNAL

RhoA/Rho-Kinase in the Cardiovascular System

(2016) Hiroaki Shimokawa et al.   CIRCULATION RESEARCH

Simultaneous Rho kinase inhibition in circulating leukocytes and in cardiovascular tissue in rats with high angiotensin converting enzyme levels

(2016) Camila Fierro et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease

(2015) Svenja Hartmann et al.   Frontiers in Pharmacology

Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells

(2015) Lijuan Kan et al.   PLoS One

When neutrophils meet T cells: Beginnings of a tumultuous relationship with underappreciated potential

(2014) Shirin Kalyan et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis

(2014) Maria Paz Ocaranza et al.   JOURNAL OF HYPERTENSION

Increased Rho-Kinase Activity in Hypertensive Patients With Left Ventricular Hypertrophy

(2013) L. Gabrielli et al.   AMERICAN JOURNAL OF HYPERTENSION

Rho-Kinase in Leukocytes

(2013) Hiroyuki Watanabe et al.   CIRCULATION JOURNAL

Rho-Kinase Activation in Patients With Heart Failure

(2013) Zhulanqiqige Do.e et al.   CIRCULATION JOURNAL

Unrestrained p38 MAPK Activation in Dusp1/4 Double-Null Mice Induces Cardiomyopathy

(2012) Mannix Auger-Messier et al.   CIRCULATION RESEARCH

Increased Rho kinase activity in congestive heart failure

(2012) Ming Dong et al.   EUROPEAN JOURNAL OF HEART FAILURE

Protective Role of the ACE2/Ang-(1–9) Axis in Cardiovascular Remodeling

(2012) María Paz Ocaranza et al.   International Journal of Hypertension

Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure

(2011) María Paz Ocaranza et al.   AMERICAN HEART JOURNAL

Mitigation of the progression of heart failure with sildenafil involves inhibition of RhoA/Rho-kinase pathway

(2011) Vinh Q. Chau et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Fasudil, a Rho-kinase inhibitor, protects against excessive endurance exercise training-induced cardiac hypertrophy, apoptosis and fibrosis in rats

(2011) Tsung-Jung Ho et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1–9) axis in experimental hypertension

(2011) María P Ocaranza et al.   JOURNAL OF HYPERTENSION

Transcriptomic biomarkers of the response of hospitalized geriatric patients admitted with heart failure. Comparison to hospitalized geriatric patients with infectious diseases or hip fracture

(2011) Thi Kim Duy Vo et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Blood Signature of Pre-Heart Failure: A Microarrays Study

(2011) Fatima Smih et al.   PLoS One

Measurement of Rho-associated kinase (ROCK) activity in humans: Validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil

(2010) Takaki Hata et al.   ATHEROSCLEROSIS

Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers

(2010) Takayuki Hidaka et al.   HYPERTENSION RESEARCH

Angiotensin-(1–9) regulates cardiac hypertrophy in vivo and in vitro

(2010) Maria Paz Ocaranza et al.   JOURNAL OF HYPERTENSION

Calcium channel blocker and Rho-associated kinase activity in patients with hypertension

(2010) Takaki Hata et al.   JOURNAL OF HYPERTENSION

ROCK1 plays an essential role in the transition from cardiac hypertrophy to failure in mice

(2010) Jianjian Shi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitogen-Activated Protein Kinases as Biomarkers of Hypertension or Cardiac Pressure Overload

(2009) María P. Ocaranza et al.   HYPERTENSION

Gene expression profiles in peripheral blood mononuclear cells of chronic heart failure patients

(2009) Claudia Cappuzzello et al.   PHYSIOLOGICAL GENOMICS

Statins inhibit Rho kinase activity in patients with atherosclerosis

(2008) Anju Nohria et al.   ATHEROSCLEROSIS

Disruption of ROCK1 gene attenuates cardiac dilation and improves contractile function in pathological cardiac hypertrophy

(2008) Jianjian Shi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY