Multiple mitochondrial thioesterases have distinct tissue and substrate specificity and CoA regulation, suggesting unique functional roles

Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences

(2018) Sandra Backes et al.   JOURNAL OF CELL BIOLOGY

Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

(2018) Natasha Fillmore et al.   MOLECULAR MEDICINE

Thioesterase superfamily member 2 promotes hepatic insulin resistance in the setting of Glycerol-3-phosphate acyltransferase 1-induced steatosis

(2018) Veronika Tillander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thioesterase-mediated control of cellular calcium homeostasis enables hepatic ER stress

(2017) Baran A. Ersoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Deactivating Fatty Acids: Acyl-CoA Thioesterase-Mediated Control of Lipid Metabolism

(2017) Veronika Tillander et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Definition of a High-Confidence Mitochondrial Proteome at Quantitative Scale

(2017) Marcel Morgenstern et al.   Cell Reports

The promiscuous enzyme medium-chain 3-keto-acyl-CoA thiolase triggers a vicious cycle in fatty-acid beta-oxidation

(2017) Anne-Claire M. F. Martines et al.   PLoS Computational Biology

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism

(2015) Miranda M. Sung et al.   CARDIOVASCULAR RESEARCH

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

(2015) Sarah E. Calvo et al.   NUCLEIC ACIDS RESEARCH

Metabolic and Tissue-Specific Regulation of Acyl-CoA Metabolism

(2015) Jessica M. Ellis et al.   PLoS One

Acyl-CoA thioesterase-2 facilitates mitochondrial fatty acid oxidation in the liver

(2014) Cynthia Moffat et al.   JOURNAL OF LIPID RESEARCH

Acyl-CoA thioesterase 9 (ACOT9) in mouse may provide a novel link between fatty acid and amino acid metabolism in mitochondria

(2013) Veronika Tillander et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cyclophilin D Modulates Mitochondrial Acetylome

(2013) Tiffany Tuyen M. Nguyen et al.   CIRCULATION RESEARCH

Acyl Coenzyme A Thioesterase 7 Regulates Neuronal Fatty Acid Metabolism To Prevent Neurotoxicity

(2013) Jessica M. Ellis et al.   MOLECULAR AND CELLULAR BIOLOGY

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

(2013) Karen van Eunen et al.   PLoS Computational Biology

Human Brown Fat Inducible Thioesterase Variant 2 Cellular Localization and Catalytic Function

(2012) Danqi Chen et al.   BIOCHEMISTRY

Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism

(2012) Hye Won Kang et al.   FASEB JOURNAL

Functional characterization of thioesterase superfamily member 1/Acyl-CoA thioesterase 11: implications for metabolic regulation

(2012) Shuxin Han et al.   JOURNAL OF LIPID RESEARCH

Acyl Coenzyme A Thioesterase Them5/Acot15 Is Involved in Cardiolipin Remodeling and Fatty Liver Development

(2012) E. Zhuravleva et al.   MOLECULAR AND CELLULAR BIOLOGY

Calorie Restriction and SIRT3 Trigger Global Reprogramming of the Mitochondrial Protein Acetylome

(2012) Alexander S. Hebert et al.   MOLECULAR CELL

Upregulation of Fatty Acyl-CoA Thioesterases in the Heart and Skeletal Muscle of Rats Fed a High-Fat Diet

(2011) Mariko Fujita et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Myocardial ATGL Overexpression Decreases the Reliance on Fatty Acid Oxidation and Protects against Pressure Overload-Induced Cardiac Dysfunction

(2011) P. C. Kienesberger et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulated expression of acyl-CoA thioesterases in the differentiation of cultured rat brown adipocytes

(2010) Atsushi Momose et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evidence for Physical Association of Mitochondrial Fatty Acid Oxidation and Oxidative Phosphorylation Complexes

(2010) Yudong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2)

(2009) Corey R. Mandel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs

(2009) Jie Wei et al.   BIOCHEMICAL JOURNAL

Essential Role for Uncoupling Protein-3 in Mitochondrial Adaptation to Fasting but Not in Fatty Acid Oxidation or Fatty Acid Anion Export

(2008) Erin L. Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY