Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4)

Type 3 inositol 1,4,5‐trisphosphate receptor is increased and enhances malignant properties in cholangiocarcinoma

(2019) Pimwipa Ueasilamongkol et al.   HEPATOLOGY

Phospholipase C delta 4 (PLCδ4) is a nuclear protein involved in cell proliferation and senescence in mesenchymal stromal stem cells

(2018) Marianna Kunrath-Lima et al.   CELLULAR SIGNALLING

Nonalcoholic fatty liver disease impairs expression of the type II inositol 1,4,5-trisphosphate receptor

(2018) Tanaporn Khamphaya et al.   HEPATOLOGY

Translocation of Epidermal Growth Factor (EGF) to the nucleus has distinct kinetics between adipose tissue-derived mesenchymal stem cells and a mesenchymal cancer cell lineage

(2018) Camila Cristina Fraga Faraco et al.   JOURNAL OF STRUCTURAL BIOLOGY

Hepatostat: Liver regeneration and normal liver tissue maintenance

(2017) George K. Michalopoulos   HEPATOLOGY

Regulation and physiological functions of mammalian phospholipase C

(2017) Yoshikazu Nakamura et al.   JOURNAL OF BIOCHEMISTRY

Nuclear Inositide Signaling Via Phospholipase C

(2017) Stefano Ratti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Inositol Trisphosphate/Calcium Signaling Pathway in Health and Disease

(2016) Michael J. Berridge   PHYSIOLOGICAL REVIEWS

A novel DAG-dependent mechanism links PKCɑ and Cyclin B1 regulating cell cycle progression

(2015) Alessandro Poli et al.   Oncotarget

Spatially Defined InsP3-Mediated Signaling in Embryonic Stem Cell-Derived Cardiomyocytes

(2014) Nidhi Kapoor et al.   PLoS One

K562 cell proliferation is modulated by PLCβ1 through a PKCα-mediated pathway

(2013) Alessandro Poli et al.   CELL CYCLE

Nuclear inositide specific phospholipase C signalling - interactions and activity

(2013) Irene Faenza et al.   FEBS Journal

Nuclear epidermal growth factor receptor interacts with transcriptional intermediary factor 2 to activate cyclin D1 gene expression triggered by the oncoprotein latent membrane protein 1

(2012) Yin Shi et al.   CARCINOGENESIS

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family

(2012) Ying-Nai Wang et al.   Cell and Bioscience

Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway

(2011) Ana Carolina De Angelis Campos et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

EGFR Nuclear Translocation Modulates DNA Repair following Cisplatin and Ionizing Radiation Treatment

(2011) G. Liccardi et al.   CANCER RESEARCH

Nuclear Translocation of Epidermal Growth Factor Receptor by Akt-dependent Phosphorylation Enhances Breast Cancer-resistant Protein Expression in Gefitinib-resistant Cells

(2011) Wei-Chien Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nucleoplasmic reticulum: form and function

(2011) Ashraf Malhas et al.   TRENDS IN CELL BIOLOGY

RNA helicase A is a DNA-binding partner for EGFR-mediated transcriptional activation in the nucleus

(2010) L. Huo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An update on nuclear calcium signalling

(2009) M. D. Bootman et al.   JOURNAL OF CELL SCIENCE

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS

(2009) M. Y. Follo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Catalytic activity of nuclear PLC-β1 is required for its signalling function during C2C12 differentiation

(2008) Giulia Ramazzotti et al.   CELLULAR SIGNALLING

Trafficking of receptor tyrosine kinases to the nucleus

(2008) Graham Carpenter et al.   EXPERIMENTAL CELL RESEARCH

Involvement of nuclear PLCβ1 in lamin B1 phosphorylation and G2/M cell cycle progression

(2008) Roberta Fiume et al.   FASEB JOURNAL

Insulin induces calcium signals in the nucleus of rat hepatocytes

(2008) Michele A. Rodrigues et al.   HEPATOLOGY

Activated Nuclear Metabotropic Glutamate Receptor mGlu5 Couples to Nuclear Gq/11Proteins to Generate Inositol 1,4,5-Trisphosphate-mediated Nuclear Ca2+Release

(2008) Vikas Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY