Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

Systemic analysis of tyrosine kinase signaling reveals a common adaptive response program in a HER2-positive breast cancer

(2019) Martin Schwill et al.   Science Signaling

Mechanical regulation of gene expression in cardiac myocytes and fibroblasts

(2019) Jeffrey J. Saucerman et al.   Nature Reviews Cardiology

Yoda1-induced phosphorylation of Akt and ERK1/2 does not require Piezo1 activation

(2018) Nathaniel G. dela Paz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation

(2018) Elizabeth L Evans et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism

(2018) Sumia A. Bageghni et al.   FASEB JOURNAL

Probing the gating mechanism of the mechanosensitive channel Piezo1 with the small molecule Yoda1

(2018) Jerome J. Lacroix et al.   Nature Communications

Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells

(2018) Josefina Inés del Mármol et al.   eLife

Mechanical regulation of cardiac fibroblast profibrotic phenotypes

(2017) Kate M. Herum et al.   MOLECULAR BIOLOGY OF THE CELL

Human cardiac fibroblasts adaptive responses to controlled combined mechanical strain and oxygen changes in vitro

(2017) Giovanni Stefano Ugolini et al.   eLife

The Soft- and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart

(2017) Kate Herum et al.   Journal of Clinical Medicine

Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells

(2017) Asuna Sugimoto et al.   Scientific Reports

Cyclin-Dependent Kinases as Coregulators of Inflammatory Gene Expression

(2016) M. Lienhard Schmitz et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Calcium Sensing Receptor Promotes Cardiac Fibroblast Proliferation and Extracellular Matrix Secretion

(2014) Xinying Zhang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cardiac fibroblast in development and wound healing

(2014) Arjun Deb et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Mechanical stretch changes coronary artery fibroblasts function by upregulating HSF1 protein expression

(2013) Jiming Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Adult cardiac fibroblast proliferation is modulated by calcium/calmodulin-dependent protein kinase II in normal and hypertrophied hearts

(2013) Tamara P. Martin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1

(2013) C. Bae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts

(2012) John K. Sinfield et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRPV4 channels mediate cardiac fibroblast differentiation by integrating mechanical and soluble signals

(2012) Ravi K. Adapala et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

510: Mechanical stretch increases production of inflammatory cytokines from cervical fibroblasts in 2D and 3D culture

(2011) Michael House et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats

(2010) Giselle C. Meléndez et al.   HYPERTENSION

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

IL-6 loss causes ventricular dysfunction, fibrosis, reduced capillary density, and dramatically alters the cell populations of the developing and adult heart

(2009) Indroneal Banerjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Modulation of Ca2+ signalling in human vascular endothelial cells by hydrogen sulfide

(2009) Claudia C. Bauer et al.   ATHEROSCLEROSIS

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS