Article
Chemistry, Multidisciplinary
Ichraf Slimani, Serap Sahin-Bolukbasi, Mustafa Ulu, Enes Evren, Nevin Gurbuz, Ilknur Ozdemir, Naceur Hamdi, Ismail Ozdemir
Summary: A series of rhodium(i) complexes with N-heterocyclic carbene ligands showed high in vitro cytotoxic activity against human cancer cells, with complex 2b exhibiting the most selective cytotoxic activity. These complexes demonstrated greater cytotoxicity against cancer cells compared to established anticancer agents cisplatin and 5-fluorouracil.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Tereza Duskova, Dharmendra S. Prajapati, Pavel Kaule, Lucie Cervenkova Stastna, Tomas Strasak, Jan Cermak
Summary: A series of imidazolium salts with specific substituents were synthesized and used as precursors for the synthesis of rhodium and iridium complexes. The complexes exhibited high fluorophilicity, making them suitable for organic-organic and organic-fluorous phase separation.
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2023)
Article
Biochemical Research Methods
Fady Nahra, Nikolaos Tzouras, Alba Collado, Steven P. Nolan
Summary: N-heterocyclic carbene gold(I) chloride and hydroxide complexes are commonly used as synthetic reagents and efficient catalysts. This study describes a straightforward and practical method for synthesizing mononuclear gold complexes with high yields, as well as the synthesis of a mononuclear gold(I) hydroxide complex and an improved synthesis method for a dinuclear gold(I) hydroxide complex. This methodology offers advantages such as the use of sustainable reaction solvents and commercially available starting materials.
Article
Chemistry, Inorganic & Nuclear
Yaru Jing, Jingxing Jiang, Yan Liu, Zhuofeng Ke
Summary: This study presents a theoretical evaluation of the electronic and steric properties of various N-Heterocyclic boryl (NHB) ligands using NHB-Ir(CO)(3) as the model complex. The results reveal the influence of substitution, backbone saturation, ring size, and heteroatoms on the NHB properties. The findings suggest that these scales are crucial for the design, application, and mechanistic understanding of NHB-based complexes or molecules.
Article
Chemistry, Multidisciplinary
Ludivine Poyac, Stefano Scoditti, Xavier Dumail, Michel Granier, Sebastien Clement, Rafael Gramage-Doria, Charles H. Devillers, Sebastien Richeter
Summary: The electronic and steric properties of NHC ligands functionalized with porphyrins were investigated. It was found that when porphyrins are used as NHC-wingtips, the catalytic activity of the neighboring NHC-Rh(I) complex in the conjugate addition reaction is significantly improved.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Lakshay Kathuria, Ashoka G. Samuelson
Summary: The enantioselective reduction of imines to chiral secondary amines was studied using chiral half-sandwich iridium complexes with N-heterocyclic carbene ligands. The optimized conditions showed good yields for ketimines with moderate enantiomeric excess. The Ir complex with phenylglycine-derived chiral NHC exhibited the highest catalytic activity and enantiomeric excess compared to other NHCs in the series.
Article
Chemistry, Inorganic & Nuclear
Nuchareenat Wiratpruk, Guneet K. Bindra, Alex Hamilton, Mark D. Hulett, Peter J. Barnard
Summary: A family of rhenium(i) tricarbonyl complexes with pyridyl-imidazolylidene or bis-imidazolylidene ligands in combination with a series of N-acetyl amino acids ligands and an acetate have been synthesized and characterized. These complexes show potential as anticancer agents, with the ability to exchange the bound carboxylate ligand with water to form cytotoxic cationic complexes. Cytotoxicity studies reveal that the complexes with the bis-imidazolylidene ligand exhibit higher toxicity compared to those with the pyridyl-imidazolylidene ligand.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Applied
Vanessa Vethacke, Vanessa Claus, Martin C. Dietl, Daniel Ehjeij, Arne Meister, Jonas F. Huber, Leon K. Paschai Darian, Matthias Rudolph, Frank Rominger, A. Stephen K. Hashmi
Summary: A variety of unsymmetric diaryl gold N-acyclic carbene (NAC) complexes were successfully synthesized by three different methods, allowing access to new complexes and overcoming previous limitations in the isonitrile route. These new complexes also proved to be successful as pre-catalysts in gold-catalyzed phenol synthesis.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Inorganic & Nuclear
Mert Olgun Karatas, Tuba Keskin, Namik Ozdemir, Hasan Kucukbay, Suat Tekin, Ahmet Mansur, Selami Gunal, Suleyman Sandal
Summary: In this study, Ag, Rh, and Ir complexes of a silyl-substituted NHC ligand were synthesized and their biological properties were investigated. The results showed that these complexes exhibited comparable or better cytotoxicity against cancer cells and antimicrobial activity compared to standard drugs.
INORGANIC CHEMISTRY COMMUNICATIONS
(2022)
Article
Chemistry, Medicinal
Tao Jia, Oumar Diane, Deepanjan Ghosh, Myriem Skander, Gaelle Fontaine, Pascal Retailleau, Joel Poupon, Jerome Bignon, Ytabelle Maga Moulai Siasia, Vincent Servajean, Nathalie Hue, Jean-Francois Betzer, Angela Marinetti, Sophie Bombard
Summary: This article introduces a new series of bimetallic platinum-(II) complexes with NHC-type bridging ligands, which exhibit cytotoxicity, cell accumulation, and DNA binding properties in cancerous cells. These complexes demonstrate significant radiosensitizing effects by inhibiting DNA repair mechanisms, leading to persistent accumulation of irradiation-induced DNA damages. This study provides the first in vitro evidence for the radiosensitizing properties of NHC-platinum complexes, suggesting their potential use in combined chemo-radiotherapy protocols.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Ludwig Zapf, Sven Peters, Ruediger Bertermann, Udo Radius, Maik Finze
Summary: This study demonstrates that the charge, coordination site number, volume, σ-donor, and π-acceptor properties of NHCs can be effectively tuned by the number of tricyanoborane substituents.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Paul Zaby, Jan Blasius, Anna K. Mueller, Steven P. Nolan, Oldamur Holloczki
Summary: The formation mechanism of metal-N-heterocyclic carbene (NHC) complexes from imidazolium salts in the presence of weak bases was investigated through theoretical methods. Quantum chemical calculations revealed that both sodium acetate and trimethylamine facilitate complex formation. Molecular dynamics simulations showed that the ionic nature of the [AuCl2](-) and imidazolium ions, as well as the sodium acetate base, keep these species associated in the reaction mixture through ion pairing. The neutral amine, however, remains mostly separated from the other reaction partners, making it a significantly less effective base.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Polymer Science
Ru He, Raquel A. Domingues, Silvano Valandro, Kirk S. Schanze
Summary: In this study, the synthesis, characterization, and application of platinum poly-yne (NPtAP) as an organic light-emitting diode (OLED) emitter were successfully demonstrated. The use of N-heterocyclic carbene (NHC) ligands with chiral 2-ethylhexyl substituents helped enhance the photoluminescence quantum yield of the platinum poly-yne, while limiting interchain interactions. The prototype solution-processed OLEDs employing NPtAP displayed yellow-green electroluminescence (EL).
Article
Chemistry, Inorganic & Nuclear
Angela Vivancos, Adrian Jimenez-Garcia, Delia Bautista, Pablo Gonzalez-Herrero
Summary: A series of bis-cyclometalated Pt(IV) complexes incorporating mesoionic aryl-NHC ligand trz with either 1-phenylpyrazole or 2-arylpyridine ligands are reported, showing phosphorescent emissions in the blue to yellow color range with high quantum yields. The addition of trz ligand leads to lower nonradiative decay rates and higher quantum efficiencies compared to homologous species with two equal 2-arylpyridine ligands. Computational calculations substantiate the effect of the carbene ligand on the energy levels and emissive properties of the complexes.
INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Angela Vivancos, Delia Bautista, Pablo Gonzalez-Herrero
Summary: This study reports the synthesis, structure, photophysical properties, and electrochemistry of the first series of Pt(IV) tris-chelates bearing cyclometalated aryl-NHC ligands. The complexes exhibit significant photostability, long-lived phosphorescence, and potential application for Pt(IV) emitters with tunable properties.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Alberto Aragon-Muriel, Bethsy A. Aguilar-Castillo, Ernesto Rufino-Felipe, Hugo Valdes, Lucero Gonzalez-Sebastian, Rebeca Nayely Osorio-Yanez, Yamil Liscano, Valente Gomez-Benitez, Dorian Polo-Ceron, David Morales-Morales
Summary: A series of non-symmetric POCOP-Pd(II) pincer complexes with aldehyde group were prepared and evaluated for their antibacterial activities. Complex 3-Pd, containing the aldehyde functionality, showed the highest activity against S. aureus ATCC 25923 strain.
Article
Chemistry, Multidisciplinary
Luis Angel Turcio-Garcia, Hugo Valdes, Antonino Arenaza-Corona, Simon Hernandez-Ortega, David Morales-Morales
Summary: A series of selenourea compounds with fluorinated fragments were synthesized and their Se-77 NMR chemical shifts were studied. The presence of more fluorine atoms in the structure caused a downfield shift of the Se-77 signal, indicating higher pi-acidity in the N-heterocycle. The position of the fluorine atom also influenced the chemical shift, with the 3-position showing the highest downfield shift.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Nicolas Puentes-Diaz, Diego Chaparro, David Morales-Morales, Areli Flores-Gaspar, Jorge Ali-Torres
Summary: Alzheimer's disease (AD) is a common form of dementia and its causes are not fully understood. High concentration of certain metal cations has been linked to the development of AD and the production of reactive oxygen species that cause neuronal damage. Multifunctional ligands have been proposed as a potential treatment to prevent or reverse the damaging effects of these metal cations. This review discusses recent advances in understanding the role of metal cations and the development of multifunctional ligands for AD.
Article
Chemistry, Medicinal
Daniel Canseco-Gonzalez, Isaac Rodriguez-Victoria, Teresa Apan-Ramirez, Alejandro O. Viviano-Posadas, Juan S. Serrano-Garcia, Antonino Arenaza-Corona, Adrian L. Orjuela, Jorge Ali-Torres, Alejandro Dorazco-Gonzalez, David Morales-Morales
Summary: A series of D-ring ethisterones substituted with 1,4-1,2,3-triazoles were synthesized through click chemistry reactions. The new compounds were characterized by various spectroscopic techniques and their crystal structures were determined. The cytotoxic activities of these derivatives were evaluated against several human cancer cell lines, and compounds (3, X=Cl) and (5, X=I) exhibited promising activity against leukemia adenocarcinoma (K562) and lung adenocarcinoma (SKLU). DNA docking simulations suggested that all compounds interacted with DNA through crosslink intrstrand p-alkyl-like interactions.
Article
Chemistry, Inorganic & Nuclear
Edgar Marin-Carrillo, Hugo Valdes, Simon Hernandez-Ortega, David Morales-Morales
Summary: Two Pd(II) complexes with bidentated [R'2(OR)P<^>P(OR)R'2] (OR = 7-(2,3-dihydroxypropyl)theophylline and R' = Ph for (1) and R' = iPr for (2)) ligands were synthesized and characterized. Their molecular structures were determined by single crystal X-ray diffraction analysis, confirming the chelating coordination of the phosphinite-theophylline ligand to the Pd(II) center. Complex (2) showed excellent catalytic activity in Suzuki-Miyaura Couplings, achieving yields of > 99% for the formation of C-C bonds under mild reaction conditions (50 degrees C, 50 W, 5 min, and 0.05 mol % of catalyst).
INORGANICA CHIMICA ACTA
(2023)
Article
Chemistry, Inorganic & Nuclear
Rafael Lopez-Sanchez, J. Roberto Pioquinto-Mendoza, Lucero Gonzalez-Sebastian, Ruben A. Toscano, Marcos Flores-Alamo, Maria Teresa Ramirez-Apan, Adrian L. Orjuela, Jorge Ali-Torres, David Morales-Morales
Summary: This study describes the synthesis of a series of Pd(II) (Pd-1-3) complexes with salen or salphen ligands. The complexes were characterized using standard spectroscopic techniques. The crystal structure analysis of complex Pd-3 revealed a distorted square planar environment for the palladium center. In addition, the in vitro cytotoxic activity of the palladium complexes Pd-1-3 against five human cancer cell lines was evaluated, and Pd-2 showed the best inhibitory activity against human prostatic adenocarcinoma (PC-3) with an IC50 of 3.8 +/- 0.4 µM. Docking calculations were also performed to support these results.
INORGANICA CHIMICA ACTA
(2023)
Article
Chemistry, Physical
Tahereh Sedaghat, Marjan Aminian, Soheila Abaee, Elham Hoveizi, Abbas Tarassoli, Azizollah Beheshti, David Morales-Morales
Summary: The new binuclear organotin(IV) complexes, (Me2Sn)2L ( 1 ) and (Ph2Sn)2L ( 2 ), were synthesized by reacting R2SnCl2 (R = Me or Ph) with bis(2-hydroxy-1-naphthaldehyde) succinic dihydrazone (H4L). The synthesized compounds were characterized by elemental analysis and IR, 1 H NMR, and 119Sn NMR spectroscopy. The crystal structure of complex 1 was determined by X-ray crystallography. Additionally, the dihydrazone ligand and its diphenyltin(IV) complex were immobilized on functionalized magnetic mesoporous silica nanoparticles and characterized using various techniques. The cytotoxicity of the synthesized compounds against A549 cancer cell lines was evaluated, and it was found that diphenyltin(IV)-loaded magnetic mesoporous silica nanoparticles showed the highest cytotoxic activity.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Pharmacology & Pharmacy
M. Fernanda Munoz Tecocoatzi, Jose C. Paez-Franco, Kenneth Rubio-Carrasco, Alejandra Nunez-Pineda, Alejandro Dorazco-Gonzalez, Ines Fuentes-Noriega, Alfredo R. Vilchis-Nestor, Lilian I. Olvera, David Morales-Morales, Juan Manuel German-Acacio
Summary: Ball-milling using neat grinding or liquid-assisted grinding with different solvents allowed the formation of various solid forms of pioglitazone hydrochloride (PGZ·HCl) and rosuvastatin calcium (RSV). By adjusting the molar ratios of the reactants, coamorphous forms with different stoichiometries were obtained. In addition, mixtures of solid forms coexisted with the coamorphous forms when the drug ratio was not stoichiometric. The dissolution profiles of these solid forms were evaluated, and a synchronized release of both drugs was observed. The coamorphous 2:1 form showed an improved dissolution rate compared to pure PGZ·HCl, which may be attributed to pH changes caused by the degradation processes of RSV.
Article
Chemistry, Medicinal
Marco Villeda-Villegas, Jose C. Paez-Franco, Guadalupe Coyote-Dotor, Alejandra Nunez-Pineda, Alejandro Dorazco-Gonzalez, Ines Fuentes-Noriega, Kenneth Rubio-Carrasco, Helen Toledo P. Jaldin, David Morales-Morales, Juan Manuel German-Acacio
Summary: A coamorphous salt in a 1:1 ratio of Fluvastatin sodium (FLV) and Pioglitazone hydrochloride (PGZ center dot HCl) can be prepared by ball milling through neat grinding (NG), while the salt-cocrystal continuum is preferably formed by liquid-assisted grinding (LAG) using ethanol (EtOH). Attempts to prepare the coamorphous salt from the salt-cocrystal continuum by neat grinding were unsuccessful. Ball milling by NG or LAG can access a great variety of solid forms (PGZ center dot HCl-FLV 1:1): coamorphous with hexane; physical mixture with ethyl acetate; salt-cocrystal continuum with EtOH; and immiscible components with water.
Review
Chemistry, Inorganic & Nuclear
Raul Colorado-Peralta, Jose Luis Olivares-Romero, Sharon Rosete-Luna, Oscar Garcia-Barradas, Viviana Reyes-Marquez, Delia Hernandez-Romero, David Morales-Morales
Summary: This article summarizes the efficient antimicrobial activity of copper complexes using thiazole and benzothiazole as ligands against different bacteria and fungi.
Article
Chemistry, Physical
Antonio Cruz-Navarro, Sharon Rosete-Luna, Jose Maria Rivera, Mario Rodriguez, Angelina Flores-Parra, Silvia Castillo-Blum, David Morales-Morales, Raul Colorado-Peralta
Summary: Two new series of heptacoordinated lanthanide(III) nitrates complexes with bbp and bdmbp were synthesized and characterized. The complexes exhibited luminescent properties and coordinated with the lanthanide(III) ion in a bidentate manner. Cytotoxic activity studies showed moderate activity of bdmbp-based complexes against HeLa cell line. (c) 2023 Elsevier B.V. All rights reserved.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Chemistry, Multidisciplinary
Nicolas Puentes-Diaz, Diego Chaparro, David Morales-Morales, Jorge Ali-Torres, Areli Flores-Gaspar
Summary: Alzheimer's disease, characterized by β-amyloid plaque formation, metal ion dysregulation, and oxidative stress, is the most common type of dementia. This study evaluated the potential pharmaceutical activity of 26 pincer compounds in the context of AD's copper ion-related oxidative stress framework. The results suggest that two compounds have potential antioxidant activity, while five compounds show promise as distributor-like compounds for AD.
Article
Chemistry, Multidisciplinary
Luis angel Turcio-Garcia, Hugo Valdes, Simon Hernandez-Ortega, Daniel Canseco-Gonzalez, David Morales-Morales
Summary: The synthesis and characterization of twelve Rh(i) complexes with fluorinated NHC ligands were described. The catalytic activity of these complexes in the arylation of aldehydes was found to be related to the number of fluorine atoms present in their structures. More fluorine atoms in the NHC ligand led to higher catalytic activity, likely due to the reduced electron-donating properties of the ligand.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Angela Lis, Viorica Gladchi, Gheorghe Duca, Sergey Travin
Summary: This work presents studies on the photochemical transformations of TU and Cys with the addition of Cu(II) or Fe(III) ions. The results show that the oxidation rate of the thiols increases significantly when Cu(II) or Fe(III) ions are added to the system. It has also been found that TU and Cys can form stable complex compounds with the studied metal ions. The oxidation rates of the thiols are found to depend on the radiation intensity and emission spectrum of the irradiation sources.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Cristiane F. A. Teixeira, Estefane I. Teixeira, J. P. C. Nascimento, M. Amilcar Junior, L. M. C. Pinto, Anderson R. L. Caires, G. B. Alcantara, Ana C. Micheletti, Victor M. Deflon, Davi F. Back, Heveline Silva, Lucas Pizzuti, Gleison Antonio Casagrande
Summary: Novel binuclear heteroleptic copper(I) complexes based on mixed DPPE/thiocarbamoyl-pyrazoline ligands were synthesized and structurally characterized. These complexes exhibited similar structural behavior around the Copper(I) atoms and showed promising antimicrobial and anticancer activities.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Chen Chen, Li Liu, Xin-Xin Zhong, Fa-Bao Li, Hai-Mei Qin
Summary: Thermally activated delayed fluorescent (TADF) Cu(I) halide complexes with short lifetimes and intense emissions were synthesized and characterized. These complexes exhibit intense green to yellow-green delayed fluorescence and are suitable for OLED devices.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Tian-Yu Zhang, Xue-Qian Wu, Heng-Yu Ruan, Yi Yuan, Le Wang, Ya-Pan Wu, Qing-Wen Han, Ruan Chi, Dong-Sheng Li
Summary: In this study, a novel Ni(II)-based metal-organic framework with good electrocatalytic oxidation performance was successfully synthesized, showing potential for direct alcohol fuel cells.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Susanta Das Baishnab, R. N. Dutta Purkayastha, Waldemar Maniukiewicz, Rosa M. Gomila, Antonio Frontera
Summary: The synthesis, structure, and DNA binding ability of three decavanadate complexes containing cationic organic moieties were reported. The complexes were characterized by various techniques and their solid-state structures were analyzed. The complexes showed interesting assembly patterns and exhibited moderately strong intercalative binding with CTDNA. Additionally, their micellization behavior in the presence of the surfactant CTAB was studied.
INORGANICA CHIMICA ACTA
(2024)
Review
Chemistry, Inorganic & Nuclear
Jubaraj B. Baruah
Summary: Isomorphous series are generated by replacing atoms or molecules to form materials with similar compositions. They allow modulation of structure and properties, and generate equivalent compositions with novel material properties. The study of stereo-electronic aspects of different equivalent compositions can improve the utility of the original composition.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Kamelah S. Al-Rashdi, Bandar A. Babgi, Ehab M. M. Ali, Bambar Davaasuren, Abdul-Hamid M. Emwas, Mariusz Jaremko, Mark G. Humphrey, Mostafa A. Hussien
Summary: Tridentate ligands were used to synthesize a set of palladium complexes, which were characterized and found to have DNA and BSA binding abilities. The complexes also showed differences in anticancer activities.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Diane Isaacs, Chandler Cox, Mark A. Bezpalko, W. Scott Kassel, William G. Dougherty
Summary: The structure and electrochemical properties of zinc(II) complexes with a face-capping ligand have been investigated, revealing the effect of the ligand on bound semiquinonate (SQ) radicals. The substitution pattern of the SQ ring plays a crucial role in determining the fate of the bound SQ radicals. Additionally, the protective pocket formed by the ligand's phenyl substituents is unable to prevent decomposition of SQ radicals with minimal steric bulk, suggesting that substitution of the SQ ring is the main contributor to their stabilization.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Xingliang Chen, Zhiqiang Jiang
Summary: Here, a series of zinc tetrahedral tetrazolate frameworks (Zn-TTFs) are presented, and it is demonstrated that rotation of carboxyl group can generate structural diversity. Compound 3 exhibits a unique zeolite-like structure, while compound 4 shows both super acid and alkali resistance.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Ankita Puri, Allison Mcaninch, Sheng Shu, Khashayar Rajabimoghadam, Maxime A. Siegler, Marcel Swart, Isaac Garcia-Bosch
Summary: In this article, the synthesis and characterization of copper, nickel, and palladium complexes bound by bidentate ligands derived from ortho-phenylenediamine are described. The complexes contain tunable H-bond donors and their crystal structures reveal intramolecular H-bonding interactions between the ligand scaffolds. Variations in the coordination sphere led to the isolation of the complexes in square-planar or twisted pseudo-tetrahedral geometries. Structural analysis showed that intramolecular H-bonding interactions can be altered by disrupting the bonds between countercations, solvent of crystallization, and ligand scaffold, resulting in changes in the geometry of the complexes. DFT calculations confirmed that Cu complexes prefer twisted geometries while Ni and Pd complexes favor square-planar geometries.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Laiane dos Santos Oliveira, Pedro Henrique de Souza Guarda, Leticia Bazilio Rosa, Gustavo Clauss Rodrigues, Daniele Daiane Affonso, Joao Ernesto de Carvalho, Igor Andrade Santos, Mark Harris, Douglas Hideki Nakahata, Jose Ricardo Sabino, Danilo Ciccone Miguel, Ana Lucia Tasca Gois Ruiz, Ana Carolina Gomes Jardim, Camilla Abbehausen
Summary: Chalcones are chemical precursors of flavonoids that have various biological properties. In this study, novel copper(II)-2'-hydroxy-4-benzyloxychalcone complexes were synthesized and evaluated for their antileishmanial, antiproliferative, and antiviral activities. The results demonstrated that these complexes showed potential effects against tumor cells, leishmania parasites, and SARS-CoV-2 virus. The study also highlighted the influence of ligand structure on biological activity.
INORGANICA CHIMICA ACTA
(2024)
Review
Chemistry, Inorganic & Nuclear
Archana Thakur, Harpreet Kaur, Vishal Tyagi
Summary: This review article discusses the findings of research on the 13C NMR spectra of di- and tri-butyltin carboxylates, highlighting the importance of 13C NMR chemical shifts in determining the chemical surroundings of carbon nuclei and their role in structure elucidation.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Qiang Zhao, Qi-Yang Li, Zhi Shen, Guo Zang, Wen-Jun Lv
Summary: In this study, five metal complexes were synthesized using a solvothermal reaction and their structures were analyzed by single crystal X-ray diffraction. Fluorescence and magnetic properties of some complexes were also investigated.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Jeremy Erb, Darcy Setter, Jake Swavey, Frederick Willits, Shawn Swavey
Summary: Three BODIPY-Ru(II) complexes were synthesized by coordinating [Ru(bpy)2Cl]+ complexes to BODIPY ligands. The spectroscopic and electrochemical properties of the complexes were characterized. The complexes exhibited intense absorption peaks due to the pi pi* transitions localized on the BODIPY core, and additional charge transfer transitions associated with the metal center. The complexes showed significant singlet oxygen generation and were able to induce photo-nicking of DNA.
INORGANICA CHIMICA ACTA
(2024)
Article
Chemistry, Inorganic & Nuclear
Sahin Reja, Dilip Sarkar, Kaushik Sarkar, Deboshmita Mukherjee, T. K. S. Fayaz, Palash Sanphui, Rajesh Kumar Das
Summary: A promising bioinspired metallocatalyst has been produced and characterized, showing high catalytic activity in oxygen dependant enzymatic radical pathway. The catalyst also exhibits inter and intra molecular H-bonding and C-H-pi interactions.
INORGANICA CHIMICA ACTA
(2024)
