Article
Biophysics
Julian C. Acasio, Courtney M. Butowicz, Christopher L. Dearth, Babak Bazrgari, Brad D. Hendershot
Summary: This study investigated trunk and pelvis kinematics, muscle forces, and resultant spinal loads in individuals with lower limb amputation (LLA), with and without chronic low back pain (LBP). The findings suggest that there are differences in trunk and pelvis kinematics between individuals with and without chronic LBP, but trunk muscle forces and spinal loads are similar regardless of LBP presence. These findings are important for understanding chronic LBP in individuals with LLA.
JOURNAL OF BIOMECHANICS
(2022)
Article
Biotechnology & Applied Microbiology
Iliana Loi, Dimitar Stanev, Konstantinos Moustakas
Summary: This study introduces a semi-automatic framework for creating subject-specific total knee replacement finite element models, which can analyze locomotion patterns and evaluate knee dynamics. By automating the finite element model development process, the framework's reliability has been validated and potential uncertainties in the models have been identified.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Xiaogai Li
Summary: The study presents a personalization framework for generating subject-specific models across the lifespan and for pathological brains with significant anatomical changes. The framework includes hierarchical multiple feature and multimodality imaging registrations, mesh morphing, and mesh grouping, shown to be efficient with a heterogeneous dataset. The generated models demonstrate competitive personalization accuracy, allowing for age-dependent and groupwise brain injury mechanisms to be studied.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Engineering, Biomedical
Keegan M. Yates, Amanda M. Agnew, Devon L. Albert, Andrew R. Kemper, Costin D. Untaroiu
Summary: Rib fractures are common thoracic injuries in motor vehicle crashes. Several human finite element models have been created to assess thoracic injury risks, but accurate prediction of rib biomechanical response is challenging. This study aimed to understand the role of modeling approaches on human rib biomechanical response and develop an accurate morphing approach for subject specific rib meshes. The results showed sensitivity to material modeling approach and highlighted the need for better techniques to model rib fracture in order to improve the biofidelity of human rib finite element models.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Franziska Geiger, Maeruan Kebbach, Danny Vogel, Volker Weissmann, Rainer Bader
Summary: A quasi-static finite element model was used to adjust the stiffness of 3D-printed insoles for patients with diabetic foot by using ankle moments and joint reaction forces. The stiffness of the insole was successfully adjusted by applying soft insole plugs in areas with high plantar pressures during walking. This method could be a valuable tool in the cost-efficient development of subject-specific 3D-printed insoles for patients with diabetic foot syndrome.
APPLIED SCIENCES-BASEL
(2023)
Article
Biophysics
M. Bahramian, N. Arjmand, M. El-Rich, M. Parnianpour
Summary: Obese individuals experience greater spinal loads during load-reaching activities, even when accounting for kinematic differences. Postural differences alone are ineffective in compensating the greater spinal loads that obese people experience.
JOURNAL OF BIOMECHANICS
(2023)
Article
Computer Science, Interdisciplinary Applications
Bong Ju Chun, In Gwun Jang
Summary: The study proposed representative static loads (RSLs) based on a general gait cycle to improve bone remodeling simulation accuracy. By sampling subject-specific static loads (SSL) from RSLs, the study reduced computing cost and errors in bone mass distribution and apparent stiffness.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Review
Biotechnology & Applied Microbiology
Ruofan Wang, Zenghui Wu
Summary: Finite element analysis (FEA) is a widely used tool that has contributed to a better understanding of the spine and its behavior, as well as assisting in the design and application of spinal interbody cages (ICs). FEA allows for thorough testing of new designs before manufacturing, examining biomechanical responses and spinal fusion processes that cannot easily be experimented upon in vivo. This paper reviews the recent progress of FEA in spinal ICs over the last six years and discusses its limitations and future advancements.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Sport Sciences
Kristof Kipp, Hoon Kim, William Wolf
Summary: The purpose of this study was to determine the muscle-specific contributions to lower extremity net joint moments during squats with different external loads. The results showed that the net joint moments at the hip, knee, and ankle all increased with higher loads. Some muscles also had increased contribution to joint moments with higher loads, but the ratio between joint moments created by certain muscle pairs did not change at the knee joint.
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2022)
Article
Orthopedics
Binglang Xiong, Peng Yang, Tianye Lin, Jingli Xu, Yong Xie, Yongliang Guo, Churong Liu, Qizhao Zhou, Qizhong Lai, Wei He, Qiushi Wei, Qingwen Zhang
Summary: This study constructs a comprehensive simulation method for analyzing the dynamics and contact stress changes of the hip joint throughout a gait cycle. Individualized simulation modeling is achieved based on gait trajectories and CT images. The combination of subject-specific gait and inverse dynamic analysis provides pre-processing parameters for more accurate biomechanical analysis of the hip joint.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2022)
Article
Biophysics
Stefan Schmid, Lukas Connolly, Greta Moschini, Michael L. Meier, Marco Senteler
Summary: Musculoskeletal models have the potential to improve diagnosis and optimize clinical treatment by predicting accurate outcomes on an individual basis. A novel skin marker-based approach was developed to model subject-specific spinal alignment, which was evaluated and shown to be feasible for inter- and intrasubject investigations using musculoskeletal simulations.
JOURNAL OF BIOMECHANICS
(2022)
Article
Engineering, Biomedical
Vanessa Ramirez, Farshid Ghezelbash, Aboulfazl Shirazi-Adl, Babak Bazrgari
Summary: Heavy deadlifts are commonly used in the U.S. Army for physical fitness screening, but their biomechanical impact and risk of low-back injury are still unknown. A study using a musculoskeletal model found that during a 68 kg deadlift, the forces on the L5-S1 spinal segment reached peak levels that exceeded the threshold for injury. Personalization and changes in lumbopelvic rhythm had minimal effects on predictions, while increasing muscle moment arms significantly decreased compressive and shearing forces. The study suggests that heavy deadlifts may pose a risk of chronic injury and low-back pain.
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING
(2023)
Article
Biology
Emily Newell, Mark Driscoll
Summary: The study investigated potential stress shielding in spinal tissue property augmentation through comparison of healthy and unilateral LBP validated finite element models. Results suggested a load allocation bias within the symptomatic unilateral LBP tissues, leading to stress shielding in the paraspinal muscles.
COMPUTERS IN BIOLOGY AND MEDICINE
(2021)
Article
Biotechnology & Applied Microbiology
Yang Song, Xuanzhen Cen, Yan Zhang, Istvan Biro, Yulei Ji, Yaodong Gu
Summary: In this study, a 3D finite element coupled model was developed and validated for investigating the biomechanical interactions between the foot and sports shoe complex during balanced standing. The simulation results showed good consistency with experimental data, indicating the potential applications of the model in optimizing footwear design.
BIOENGINEERING-BASEL
(2022)
Article
Engineering, Biomedical
Amin Kassab-Bachi, Nishant Ravikumar, Ruth K. Wilcox, Alejandro F. Frangi, Zeike A. Taylor
Summary: The study used statistical shape modeling to investigate the impact of shape features on intradiscal pressure and facet contact pressure. The results showed that the first shape mode had the largest correlation and contribution to these pressures, with the largest geometric variation observed in the annulus-nucleus ratio.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Biophysics
F. Ghezelbash, A. Shirazi-Adl, N. Arjmand, Z. El-Ouaaid, A. Plamondon, J. R. Meakin
JOURNAL OF BIOMECHANICS
(2016)
Article
Computer Science, Interdisciplinary Applications
Farshid Ghezelbash, Navid Arjmand, Aboulfazl Shirazi-Adl
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
(2015)