Developmental Plasticity and Cellular Reprogramming in Caenorhabditis elegans

The multipotency-to-commitment transition in Caenorhabditis elegans -implications for reprogramming from cells to organs

(2018) Erik A. Spickard et al.   FEBS LETTERS

Wound healing, cellular regeneration and plasticity: the elegans way

(2018) Laura Vibert et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramming during the oocyte-to-embryo transition in Caenorhabditis elegans

(2018) Christina Fassnacht et al.   PLoS Genetics

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

(2018) Andreia S. Bernardo et al.   Biology Open

FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells

(2018) Ena Kolundzic et al.   DEVELOPMENTAL CELL

MRG-1/MRG15 Is a Barrier for Germ Cell to Neuron Reprogramming in Caenorhabditis elegans

(2018) Martina Hajduskova et al.   GENETICS

Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates

(2017) Moritz Mall et al.   NATURE

ELLI-1, a novel germline protein, modulates RNAi activity and P-granule accumulation in Caenorhabditis elegans

(2017) Karolina M. Andralojc et al.   PLoS Genetics

Coordinated control of terminal differentiation and restriction of cellular plasticity

(2017) Tulsi Patel et al.   eLife

Natural and induced direct reprogramming: mechanisms, concepts and general principles — from the worm to vertebrates

(2016) Sarah F Becker et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Transorganogenesis and transdifferentiation in C. elegans are dependent on differentiated cell identity

(2016) Misty R. Riddle et al.   DEVELOPMENTAL BIOLOGY

The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and Plasticity

(2016) Meera V. Sundaram et al.   GENETICS

Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons

(2016) Stefanie Seelk et al.   eLife

The Caenorhabditis elegans Excretory System: A Model for Tubulogenesis, Cell Fate Specification, and Plasticity

(2016) Meera V. Sundaram et al.   GENETICS

Glia-derived neurons are required for sex-specific learning in C. elegans

(2015) Michele Sammut et al.   NATURE

Recruitment of RNA polymerase II by the pioneer transcription factor PHA-4

(2015) H.- T. Hsu et al.   SCIENCE

Glial Development and Function in the Nervous System ofCaenorhabditis elegans

(2015) Shai Shaham   Cold Spring Harbor Perspectives in Biology

A robust transcriptional program in newts undergoing multiple events of lens regeneration throughout their lifespan

(2015) Konstantinos Sousounis et al.   eLife

Reprogramming of the chick retinal pigmented epithelium after retinal injury

(2014) Agustin Luz-Madrigal et al.   BMC BIOLOGY

Germ-Granule Components Prevent Somatic Development in the C. elegans Germline

(2014) Dustin L. Updike et al.   CURRENT BIOLOGY

A non-cell-autonomous role for Ras signaling in C. elegans neuroblast delamination

(2014) J. M. Parry et al.   DEVELOPMENT

Distinct chromatin organization in the germ line founder cell of theCaenorhabditis elegansembryo

(2014) Lenka Vágnerová et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Variations in the Efficiency of Lineage Marking and Ablation Confound Distinctions between Myogenic Cell Populations

(2014) Glenda Comai et al.   DEVELOPMENTAL CELL

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

The birth of embryonic pluripotency

(2014) T. Boroviak et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The molecular underpinnings of totipotency

(2014) S. M. Morgani et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Sequential histone-modifying activities determine the robustness of transdifferentiation

(2014) S. Zuryn et al.   SCIENCE

Activation of Neuronal Gene Expression by the JMJD3 Demethylase Is Required for Postnatal and Adult Brain Neurogenesis

(2014) Dae Hwi Park et al.   Cell Reports

The SET-2/SET1 Histone H3K4 Methyltransferase Maintains Pluripotency in the Caenorhabditis elegans Germline

(2014) Valérie J. Robert et al.   Cell Reports

Molecular conservation of metazoan gut formation: evidence from expression of endomesoderm genes in Capitella teleta (Annelida)

(2014) Michael J Boyle et al.   EvoDevo

The TRIM-NHL Protein LIN-41 Controls the Onset of Developmental Plasticity in Caenorhabditis elegans

(2014) Cristina Tocchini et al.   PLoS Genetics

Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons

(2013) Orly L. Wapinski et al.   CELL

Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor

(2013) M. R. Riddle et al.   DEVELOPMENT

Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo

(2013) Caroline Rouaux et al.   NATURE CELL BIOLOGY

Unravelling stem cell dynamics by lineage tracing

(2013) Cédric Blanpain et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone chaperone FACT action during transcription through chromatin by RNA polymerase II

(2013) F.-K. Hsieh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regeneration and Transdetermination in Drosophila Imaginal Discs

(2012) Melanie I. Worley et al.   Annual Review of Genetics

piRNAs Can Trigger a Multigenerational Epigenetic Memory in the Germline of C. elegans

(2012) Alyson Ashe et al.   CELL

piRNAs Initiate an Epigenetic Memory of Nonself RNA in the C. elegans Germline

(2012) Masaki Shirayama et al.   CELL

Essential role for Notch signaling in restricting developmental plasticity

(2012) N. J.- V. Djabrayan et al.   GENES & DEVELOPMENT

Notch and the Awesome Power of Genetics

(2012) Iva Greenwald   GENETICS

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality

(2012) Bethany A. Buckley et al.   NATURE

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity

(2012) Erik C Andersen et al.   NATURE GENETICS

Members of the NODE (Nanog and Oct4-associated deacetylase) complex and SOX-2 promote the initiation of a natural cellular reprogramming event in vivo

(2012) K. Kagias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Removal of Polycomb Repressive Complex 2 Makes C. elegans Germ Cells Susceptible to Direct Conversion into Specific Somatic Cell Types

(2012) Tulsi Patel et al.   Cell Reports

Antagonism between MES-4 and Polycomb Repressive Complex 2 Promotes Appropriate Gene Expression in C. elegans Germ Cells

(2012) Laura J. Gaydos et al.   Cell Reports

Two Distinct Repressive Mechanisms for Histone 3 Lysine 4 Methylation through Promoting 3′-End Antisense Transcription

(2012) Thanasis Margaritis et al.   PLoS Genetics

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Reprogramming Factor Expression Initiates Widespread Targeted Chromatin Remodeling

(2011) Richard P. Koche et al.   Cell Stem Cell

Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons

(2011) Samuele Marro et al.   Cell Stem Cell

Notch and Ras promote sequential steps of excretory tube development in C. elegans

(2011) Ishmail Abdus-Saboor et al.   DEVELOPMENT

Direct in vivo cellular reprogramming involves transition through discrete, non-pluripotent steps

(2011) J. P. Richard et al.   DEVELOPMENT

synMuv B proteins antagonize germline fate in the intestine and ensure C. elegans survival

(2011) L. N. Petrella et al.   DEVELOPMENT

Caenorhabditis elegans as a platform for molecular quantitative genetics and the systems biology of natural variation

(2011) BRYN E. GAERTNER et al.   Genetics Research

H3K36 Methylation Antagonizes PRC2-mediated H3K27 Methylation

(2011) Wen Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Direct lineage conversions: unnatural but useful?

(2011) Thomas Vierbuchen et al.   NATURE BIOTECHNOLOGY

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy

(2011) Jem A. Efe et al.   NATURE CELL BIOLOGY

Coordinated regulation of cholinergic motor neuron traits through a conserved terminal selector gene

(2011) Paschalis Kratsios et al.   NATURE NEUROSCIENCE

Direct reprogramming of mouse fibroblasts to neural progenitors

(2011) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CCAAT/enhancer binding protein   (C/EBP )-induced transdifferentiation of pre-B cells into macrophages involves no overt retrodifferentiation

(2011) A. Di Tullio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct cellular reprogramming in Caenorhabditis elegans : facts, models, and promises for regenerative medicine

(2011) Steven Zuryn et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Barrett's metaplasia: molecular mechanisms and nutritional influences

(2010) Jonathan M.W. Slack et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Endoderm development in Caenorhabditis elegans: The synergistic action of ELT-2 and -7 mediates the specification→differentiation transition

(2010) Erica M. Sommermann et al.   DEVELOPMENTAL BIOLOGY

The conserved role and divergent regulation of foxa, a pan-eumetazoan developmental regulatory gene

(2010) Smadar Ben-Tabou de-Leon   DEVELOPMENTAL BIOLOGY

Histone H3 Lysine 4 di-methylation: A novel mark for transcriptional fidelity?

(2010) Marina Pinskaya et al.   Epigenetics

A Strategy for Direct Mapping and Identification of Mutations by Whole-Genome Sequencing

(2010) Steven Zuryn et al.   GENETICS

Direct conversion of human fibroblasts to multilineage blood progenitors

(2010) Eva Szabo et al.   NATURE

Emerging properties of animal gene regulatory networks

(2010) Eric H. Davidson   NATURE

Open chromatin in pluripotency and reprogramming

(2010) Alexandre Gaspar-Maia et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular and cellular aspects of amphibian lens regeneration

(2010) Jonathan J. Henry et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Direct Conversion of C. elegans Germ Cells into Specific Neuron Types

(2010) B. Tursun et al.   SCIENCE

JNK Signalling Controls Remodelling of the Segment Boundary through Cell Reprogramming during Drosophila Morphogenesis

(2010) Melanie Gettings et al.   PLOS BIOLOGY

The Histone H3K36 Methyltransferase MES-4 Acts Epigenetically to Transmit the Memory of Germline Gene Expression to Progeny

(2010) Andreas Rechtsteiner et al.   PLoS Genetics

The Molecular Basis of Organ Formation: Insights From the C. elegans Foregut

(2009) Susan E. Mango   Annual Review of Cell and Developmental Biology

The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors

(2009) Jens C. Schwamborn et al.   CELL

An elegant miRror: microRNAs in stem cells, developmental timing and cancer

(2009) Rachael A. Nimmo et al.   CHROMOSOMA

The Polycomb Complex Protein mes-2/E(z) Promotes the Transition from Developmental Plasticity to Differentiation in C. elegans Embryos

(2009) T. Yuzyuk et al.   DEVELOPMENTAL CELL

Translational Repression of Cyclin E Prevents Precocious Mitosis and Embryonic Gene Activation during C. elegans Meiosis

(2009) Bjoern Biedermann et al.   DEVELOPMENTAL CELL

RNA recognition by the embryonic cell fate determinant and germline totipotency factor MEX-3

(2009) J. M. Pagano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

unc-3-dependent repression of specific motor neuron fates in Caenorhabditis elegans

(2008) Brinda Prasad et al.   DEVELOPMENTAL BIOLOGY

ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult

(2008) James D. McGhee et al.   DEVELOPMENTAL BIOLOGY

The Tumor Suppressors Brat and Numb Regulate Transit-Amplifying Neuroblast Lineages in Drosophila

(2008) Sarah K. Bowman et al.   DEVELOPMENTAL CELL

Intraspecific evolution of the intercellular signaling network underlying a robust developmental system

(2008) J. Milloz et al.   GENES & DEVELOPMENT

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

(2008) Ralph A. Neumüller et al.   NATURE

Switch of rhodopsin expression in terminally differentiated Drosophila sensory neurons

(2008) Simon G. Sprecher et al.   NATURE

In vivo reprogramming of adult pancreatic exocrine cells to β-cells

(2008) Qiao Zhou et al.   NATURE

Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells

(2008) Jiancong Liang et al.   NATURE CELL BIOLOGY

A Caenorhabditis elegans model for epithelial-neuronal transdifferentiation

(2008) S. Jarriault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Properties of developmental gene regulatory networks

(2008) E. H. Davidson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA