ATF7IP regulates SETDB1 nuclear localization and increases its ubiquitination

Heterochromatic foci and transcriptional repression by an unstructured MET-2/SETDB1 co-factor LIN-65

(2019) Colin E. Delaney et al.   JOURNAL OF CELL BIOLOGY

Essential roles of Windei and nuclear monoubiquitination of Eggless/ SETDB 1 in transposon silencing

(2019) Ken Osumi et al.   EMBO REPORTS

A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells

(2018) Kei Fukuda et al.   GENOME RESEARCH

A somatic role for the histone methyltransferase Setdb1 in endogenous retrovirus silencing

(2018) Masaki Kato et al.   Nature Communications

Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation inC. elegansembryos

(2018) Beste Mutlu et al.   Science Advances

Tri-methylation of ATF7IP by G9a/GLP recruits the chromodomain protein MPP8

(2018) Takeshi Tsusaka et al.   Epigenetics & Chromatin

­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­

(2017) Trinna L. Cuellar et al.   JOURNAL OF CELL BIOLOGY

Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation

(2017) Laure Ferry et al.   MOLECULAR CELL

Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP

(2016) Aravind Basavapathruni et al.   BIOCHEMISTRY

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes

(2016) S. Koide et al.   BLOOD

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells

(2016) Alessandra Pasquarella et al.   DEVELOPMENT

The methyltransferaseSetdb1is essential for meiosis and mitosis in mouse oocytes and early embryos

(2016) Angeline Eymery et al.   DEVELOPMENT

A Histone Methyltransferase ESET Is Critical for T Cell Development

(2016) Shoichi Takikita et al.   JOURNAL OF IMMUNOLOGY

E3-Independent Constitutive Monoubiquitination Complements Histone Methyltransferase Activity of SETDB1

(2016) Lidong Sun et al.   MOLECULAR CELL

Ubiquitination of Lysine 867 of the Human SETDB1 Protein Upregulates Its Histone H3 Lysine 9 (H3K9) Methyltransferase Activity

(2016) Kenji Ishimoto et al.   PLoS One

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex

(2016) Richard T. Timms et al.   Cell Reports

Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse

(2016) Jeesun Kim et al.   PLoS Genetics

Analysis of the subcellular localization of the human histone methyltransferase SETDB1

(2015) Keisuke Tachibana et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Histone methylation modifiers in cellular signaling pathways

(2015) Hunain Alam et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation

(2015) Yoshihiro Matsumura et al.   MOLECULAR CELL

Sound of silence: the properties and functions of repressive Lys methyltransferases

(2015) Chiara Mozzetta et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The histone methyltransferase SETDB1 represses endogenous and exogenous retroviruses in B lymphocytes

(2015) Patrick L. Collins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells

(2015) Peter J. Thompson et al.   PLoS Genetics

Setdb1is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells

(2014) Sheng Liu et al.   GENES & DEVELOPMENT

UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination

(2014) Friederike Hans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

(2014) Dirk Heckl et al.   NATURE BIOTECHNOLOGY

The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance

(2014) Michael Waterfield et al.   NATURE IMMUNOLOGY

The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation

(2014) Alissa Minkovsky et al.   Epigenetics & Chromatin

ESET histone methyltransferase is essential to hypertrophic differentiation of growth plate chondrocytes and formation of epiphyseal plates

(2013) Liu Yang et al.   DEVELOPMENTAL BIOLOGY

ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development

(2013) Kevin A. Lawson et al.   FEBS LETTERS

Regulated nuclear entry of over-expressed Setdb1

(2013) Sunwha Cho et al.   GENES TO CELLS

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

(2013) Hiroko Koike-Yusa et al.   NATURE BIOTECHNOLOGY

Emerging roles for chromatin as a signal integration and storage platform

(2013) Aimee I. Badeaux et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development

(2012) S.-L. Tan et al.   DEVELOPMENT

DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs

(2011) Mohammad M. Karimi et al.   Cell Stem Cell

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

(2011) Yoko Hayashi-Takanaka et al.   NUCLEIC ACIDS RESEARCH

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

ERG-associated protein with SET domain (ESET)-Oct4 interaction regulates pluripotency and represses the trophectoderm lineage

(2009) Leng-Siew Yeap et al.   Epigenetics & Chromatin

Windei, the Drosophila Homolog of mAM/MCAF1, Is an Essential Cofactor of the H3K9 Methyl Transferase dSETDB1/Eggless in Germ Line Development

(2009) Carmen M. Koch et al.   PLoS Genetics