Therapeutic targeting of circ‐ CUX 1 / EWSR 1/ MAZ axis inhibits glycolysis and neuroblastoma progression

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress

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Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization

(2018) Dan Li et al.   CANCER RESEARCH

LDHA in neuroblastoma is associated with poor outcome and its depletion decreases neuroblastoma growth independent of aerobic glycolysis

(2018) Carmen Dorneburg et al.   CLINICAL CANCER RESEARCH

HPSE enhancer RNA promotes cancer progression through driving chromatin looping and regulating hnRNPU/p300/EGR1/HPSE axis

(2018) Wanju Jiao et al.   ONCOGENE

WW domain-binding protein 2 acts as an oncogene by modulating the activity of the glycolytic enzyme ENO1 in glioma

(2018) Shuai Chen et al.   Cell Death & Disease

Armadillo repeat containing 12 promotes neuroblastoma progression through interaction with retinoblastoma binding protein 4

(2018) Dan Li et al.   Nature Communications

The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells

(2017) Huiwu Ouyang et al.   NUCLEIC ACIDS RESEARCH

Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer

(2017) A R Rowson-Hodel et al.   ONCOGENE

KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the KrasG12D p53flox/flox model

(2017) C-C Weng et al.   ONCOGENE

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

Metabolic Plasiticy in Cancers—Distinct Role of Glycolytic Enzymes GPI, LDHs or Membrane Transporters MCTs

(2017) Maša Ždralević et al.   Frontiers in Oncology

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

(2016) Xinjian Li et al.   MOLECULAR CELL

Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells

(2016) S Y Lim et al.   ONCOGENE

EWS and FUS bind a subset of transcribed genes encoding proteins enriched in RNA regulatory functions

(2015) Yonglun Luo et al.   BMC GENOMICS

Intelectin 1 suppresses the growth, invasion and metastasis of neuroblastoma cells through up-regulation of N-myc downstream regulated gene 2

(2015) Dan Li et al.   Molecular Cancer

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA circularization strategies in vivo and in vitro

(2015) Sonja Petkovic et al.   NUCLEIC ACIDS RESEARCH

CTCF cooperates with noncoding RNA MYCNOS to promote neuroblastoma progression through facilitating MYCN expression

(2015) X Zhao et al.   ONCOGENE

Genetic abnormalities in adolescents and young adults with neuroblastoma: A report from the Italian Neuroblastoma Group

(2015) Katia Mazzocco et al.   PEDIATRIC BLOOD & CANCER

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP

(2015) Liangliang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

2-Deoxy-D-glucose targeting of glucose metabolism in cancer cells as a potential therapy

(2014) Dongsheng Zhang et al.   CANCER LETTERS

circBase: a database for circular RNAs

(2014) Petar Glažar et al.   RNA

Circular RNAs: diversity of form and function

(2014) Erika Lasda et al.   RNA

Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1

(2014) Xiaoyu Ma et al.   Nature Communications

catRAPID omics: a web server for large-scale prediction of protein-RNA interactions

(2013) F. Agostini et al.   BIOINFORMATICS

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect

(2013) Fan Yang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

MAZ-binding G4-decoy with locked nucleic acid and twisted intercalating nucleic acid modifications suppresses KRAS in pancreatic cancer cells and delays tumor growth in mice

(2013) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Cutl1: A potential target for cancer therapy

(2012) Kuan-can Liu et al.   CELLULAR SIGNALLING

Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma

(2012) Michiel Smits et al.   FASEB JOURNAL

Targeting aerobic glycolysis: 3-bromopyruvate as a promising anticancer drug

(2012) Simone Cardaci et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes

(2012) Jan J. Molenaar et al.   NATURE

MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha

(2012) H Zhang et al.   ONCOGENE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

EWS/FLI1 Oncogene Activates Caspase 3 Transcription and Triggers Apoptosis In vivo

(2010) E. J. Sohn et al.   CANCER RESEARCH

A screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects

(2010) Jesper B. Bramsen et al.   NUCLEIC ACIDS RESEARCH

p110 CUX1 Homeodomain Protein Stimulates Cell Migration and Invasion in Part through a Regulatory Cascade Culminating in the Repression of E-cadherin and Occludin

(2009) Valerie Kedinger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY