期刊
DOCUMENTA OPHTHALMOLOGICA
卷 140, 期 2, 页码 95-101出版社
SPRINGER
DOI: 10.1007/s10633-019-09730-6
关键词
Clinical standards; Electroretinogram (ERG); Full-field ERG; International Society for Clinical Electrophysiology of Vision (ISCEV); S-cone ERG; Short-wavelength-sensitive cone ERG; Retinopathy; Retinal dystrophy
The International Society for Clinical Electrophysiology of Vision (ISCEV) standard for full-field electroretinography (ERG) describes a minimum procedure for testing generalized retinal function but encourages more extensive testing. This extended protocol describes a method of assessing the function of the short-wavelength-sensitive cone (S-cone) retinal pathway, using a short-wavelength flash superimposed on a background that saturates the rods and adapts the L/M-cones to elicit a response, known as the S-cone ERG. Stimulus parameters such as the strength and luminance of the flash and background, respectively, and their spectral and temporal characteristics are specified. As a complement to the ISCEV standard, testing the S-cone ERG enables further characterization of light-adapted retinal function and may refine diagnosis of some retinal disorders. Typical applications are described including use in the diagnosis of rod monochromacy and S-cone monochromacy, identification and investigation of cone On-bipolar cell dysfunction and use of the technique to confirm the diagnosis of enhanced S-cone syndrome.
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