Role of Zinc Supplementation in Testicular and Epididymal Damages in Diabetic Rat: Involvement of Nrf2, SOD1, and GPX5

Sodium valproate ameliorates diabetes-induced fibrosis and renal damage by the inhibition of histone deacetylases in diabetic rat

(2015) Sabbir Khan et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Zinc treatment prevents type 1 diabetes-induced hepatic oxidative damage, endoplasmic reticulum stress, and cell death, and even prevents possible steatohepatitis in the OVE26 mouse model: Important role of metallothionein

(2015) Tingting Liang et al.   TOXICOLOGY LETTERS

Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function

(2014) Yonggang Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Zinc protects cyclophosphamide-induced testicular damage in rat: Involvement of metallothionein, tesmin and Nrf2

(2014) Krishna Prahlad Maremanda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Zinc is essential for the transcription function of Nrf2 in human renal tubule cellsin vitroand mouse kidneyin vivounder the diabetic condition

(2014) Bing Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Impact of the discovery of human zinc deficiency on health

(2014) Ananda S. Prasad   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

The role of metallothionein-3 in streptozotocin-induced beta-islet cell death and diabetes in mice

(2014) Hyae-Ran Byun et al.   Metallomics

Protection by sulforaphane from type 1 diabetes-induced testicular apoptosis is associated with the up-regulation of Nrf2 expression and function

(2014) Xin Jiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Blood Metals Concentration in Type 1 and Type 2 Diabetics

(2013) Giovanni Forte et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Zinc protects against diabetes-induced pathogenic changes in the aorta: roles of metallothionein and nuclear factor (erythroid-derived 2)-like 2

(2013) Xiao Miao et al.   Cardiovascular Diabetology

Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation

(2013) A. Taylor et al.   HUMAN REPRODUCTION

Impact of the Discovery of Human Zinc Deficiency on Health

(2013) Ananda S. Prasad   JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION

Telmisartan ameliorates germ cell toxicity in the STZ-induced diabetic rat: Studies on possible molecular mechanisms

(2013) S. Kushwaha et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model

(2013) Xin Jiang et al.   TOXICOLOGY LETTERS

Zinc Supplementation Attenuates Metallothionein and Oxidative Stress Changes in Kidney of Streptozotocin-Induced Diabetic Rats

(2012) Dervis Özcelik et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Expression of cyclooxygenase-1 (COX-1) and COX-2 in human male gametes from normal patients, and those with varicocele and diabetes: a potential molecular marker for diagnosing male infertility disorders

(2012) I. Perrotta et al.   JOURNAL OF ANATOMY

Effects of Zn deficiency, antioxidants, and low-dose radiation on diabetic oxidative damage and cell death in the testis

(2012) Yuguang Zhao et al.   TOXICOLOGY MECHANISMS AND METHODS

The role of zinc in the prevention of diabetic cardiomyopathy and nephropathy

(2012) Bing Li et al.   TOXICOLOGY MECHANISMS AND METHODS

Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis

(2012) R Jayawardena et al.   Diabetology & Metabolic Syndrome

Glutathione Peroxidases at Work on Epididymal Spermatozoa: An Example of the Dual Effect of Reactive Oxygen Species on Mammalian Male Fertilizing Ability

(2011) A. Noblanc et al.   JOURNAL OF ANDROLOGY

Zinc deficiency exacerbates diabetic down-regulation of Akt expression and function in the testis: essential roles of PTEN, PTP1B and TRB3

(2011) Yuguang Zhao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effect of zinc supplementation on the distribution of various elements in the serum of diabetic rats subjected to an acute swimming exercise

(2011) Mursel Bicer et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Enalapril reduces germ cell toxicity in streptozotocin-induced diabetic rat: investigation on possible mechanisms

(2011) S. Kushwaha et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies

(2011) Tom L. Van Belle et al.   PHYSIOLOGICAL REVIEWS

Tolerance of Spermatogonia to Oxidative Stress Is Due to High Levels of Zn and Cu/Zn Superoxide Dismutase

(2011) Fritzie T. Celino et al.   PLoS One

Investigation on sodium valproate induced germ cell damage, oxidative stress and genotoxicity in male Swiss mice

(2011) Sabbir Khan et al.   REPRODUCTIVE TOXICOLOGY

Zinc Content in Epididymal Spermatozoa of Metoclopramide-Treated Rats

(2010) B. KAMINSKA et al.   ANDROLOGIA

Antioxidant Systems and Oxidative Stress in the Testes

(2010) R. John Aitken et al.   Oxidative Medicine and Cellular Longevity

Low zinc in drinking water is associated with the risk of type 1 diabetes in children

(2010) Ulf Samuelsson et al.   PEDIATRIC DIABETES

Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice

(2010) Yuguang Zhao et al.   TOXICOLOGY LETTERS

Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity 1

(2009) E. Chabory et al.   JOURNAL OF ANIMAL SCIENCE

Expression of E-SOD, GPX5 mRNAs and immunoexpression of Cu/ZnSOD in epididymal epithelial cells of finasteride-treated rats

(2008) A. Kolasa et al.   ANDROLOGIA