Review
Medicine, General & Internal
Hung-Chi Lue, Yi-Chang Su, Sunny Jui-Shan Lin, Yi-Chia Huang, Yung-Hsien Chang, I-Hsin Lin, Sze-Piao Yang
Summary: This study aimed to promote the integration of traditional Chinese medicine and western medicine, and called for the development of regulations and guidelines to facilitate clinical trials. Most experts believe that integrative TC&WM could be the most useful and advanced healthcare medicine in the future.
JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
(2021)
Review
Plant Sciences
Herong Cui, Songjie Han, Yanan Dai, Wei Xie, Rui Zheng, Yang Sun, Xiaofeng Xia, Xiaopeng Deng, Yaru Cao, Mei Zhang, Hongcai Shang
Summary: This study summarizes the research progress on the mechanisms of gut microbiota in the occurrence and prognosis of heart failure from 1987 to 2022, as well as the role of integrative traditional Chinese and Western medicine. The findings show that heart failure patients have a decrease in beneficial bacteria such as Bacillus mimics and Lactobacillus in the intestinal flora, an increase in harmful flora like thick-walled flora, and an increase in inflammatory response and serum expression of trimethylamine oxide (TMAO).
Article
Integrative & Complementary Medicine
Kam Wa Chan, Tak Yee Chow, Kam Yan Yu, Yibin Feng, Lixing Lao, Zhaoxiang Bian, Vivian Taam Wong, Sydney Chi-Wai Tang
Summary: This retrospective cohort study evaluates the effectiveness, safety profile, and prescription pattern of an integrative medicine service program for patients with diabetes and chronic kidney disease in Hong Kong. The results show that individualized add-on Chinese medicine treatment significantly preserves kidney function and is well tolerated.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2022)
Article
Oncology
Jietao Lin, Lingling Sun, Hanrui Chen, Wenmin Chen, Zexin Zhang, Yang Cao, Lizhu Lin
Summary: This planned multicenter observational study aims to assess the overall survival rate of patients with stage IIIb-IVb non-small cell lung cancer receiving integrated Chinese and Western medicine, and analyze the factors related to prognosis. The study will enroll patients from March 1, 2019 to December 31, 2025 and follow them for 5 years. Data on demographics, treatment, overall survival, and prognostic factors will be collected. The study protocol has been reviewed by the institutional review board and ethics committee, and informed consent will be obtained from all patients before enrollment. Trial registration number: ChiCTR1900021430.
INTEGRATIVE CANCER THERAPIES
(2023)
Review
Integrative & Complementary Medicine
Zhang Qiao-li, Lei Ya-ling, Deng Yan, Ma Rui-lin, Ding Xue-song, Xue Wei, Sun Ai-jun
Summary: This review evaluates the progress of treatment for diminished ovarian reserve (DOR) in both Western medicine and Chinese medicine, highlighting the characteristics of each treatment approach.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2023)
Review
Chemistry, Medicinal
Rao Fu, Jie Li, Huatao Yu, Yang Zhang, Zhihong Xu, Cathie Martin
Summary: The success of Western scientific medicine can be seen in the improvements in life expectancy and reduction in infectious diseases, but challenges remain with drug-resistant infections and new diseases. Traditional Chinese Medicine offers personalized treatments based on centuries of practice, complementing Western medicine for comprehensive care. Combination of WSM and TCM can benefit patients in terms of speed and efficacy of recovery or disease management.
MEDICINAL RESEARCH REVIEWS
(2021)
Review
Endocrinology & Metabolism
Natural Chu, Juliana C. N. Chan, Elaine Chow
Summary: Pharmacomicrobiomics investigates the interactions between foreign compounds and the gut microbiome, which play a significant role in the efficacy, side effects, and toxicity of the compounds. Glucose lowering drugs work by regulating insulin and energy disposal. In addition to genetic, ecological, and lifestyle factors, maintaining a balanced gut microbiome is crucial for human health. Different compositions of microbiota can influence patients' responses to glucose-lowering drugs. This article summarizes the differences in gut microbiota composition between individuals with type 2 diabetes and healthy individuals, and explores how Western Medicine and Traditional Chinese Medicine can shape the gut microbiota to improve immunity and metabolic health.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Integrative & Complementary Medicine
Chi Him Sum, Jessica Ching, Hongwei Zhang, Steven Loo, Cho Wing Lo, Mei Kwan Lai, Pui Kuan Cheong, Chau Leung Yu, Zhi-Xiu Lin
Summary: This study systematically reviewed the clinical effectiveness and safety of integrated Chinese-Western medicine (ICWM) for atopic dermatitis (AD). The results showed that ICWM was superior to Western medicine alone in improving clinical severity of AD, health-related quality of life, long term control of AD, patients/investigator global score, and serum IgE level, with comparable adverse events. However, more evidence is needed for conclusive decision-making.
Review
Oncology
Abdelhakim Bouyahya, Nasreddine El Omari, Saad Bakrim, Naoufal El Hachlafi, Abdelaali Balahbib, Polrat Wilairatana, Mohammad S. Mubarak
Summary: Several dietary phenolic compounds isolated from medicinal plants have significant anticancer effects. They induce apoptosis, autophagy, telomerase inhibition, and angiogenesis. These compounds increase the effectiveness of conventional chemotherapy drugs and have shown remarkable therapeutic results in treating certain cancers. However, chemoresistance is still a challenge in cancer treatment, and combining multiple anticancer agents can help overcome resistance and improve therapeutic efficacy.
Review
Cardiac & Cardiovascular Systems
Yingxin Wang, Herong Cui, Liwen Li, Yajing Cao, Hanyun Qu, Halisi Ailina, Zhili Dou, Chuwei Tang, Wanli Qin, Chenlu Wang, Xue Yang, Shixing Feng, Yixing Liu, Dongran Han
Summary: Digitalization has emerged as a new trend in healthcare, offering great potential and creating unique opportunities and challenges. This article reviews the current status and impact of digital healthcare on combined Chinese and Western medical therapies and discusses the prospects for developing an active role for digitalization in managing acute heart failure. Its objective is to support cardiovascular health maintenance in the population.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Zhi-Yu Li, Zhi-Jun Xie, Hai-Chang Li, Jian-Jian Wang, Xiang-Hui Wen, Shou-Yuan Wu, Jiao Chen, Juan-Juan Zhang, Lin Li, Qiang-Qiang Guo, Qiu-Ping Liu, Hui Lan, Yue-Peng Jiang, Dian-Ming Li, Xiao-Feng Xu, Si-Yue Song, Ming Zhang, Shan Fang, Wei-Dong Lai, Yi-Ni Gao, Feng-Qi Zhang, Wen-Qing Luo, Yu Lou, Wu Chen, Xia-Feng Zhang, Ke-Er Wang, Ming-Qian Zhou, Yuan-Fang He, An-Ran Xi, Yan Gao, Yi Zhang, Yao-Long Chen, Cheng-Ping Wen
Summary: This article introduces the development of guidelines for the integrated treatment of severe COVID-19 with TCM and western medicine, based on the WHO handbook, the GRADE system, and the RIGHT reporting items. The aim is to provide clinical guidance and decision basis for healthcare professionals.
PHARMACOLOGICAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Tushar Ranjan Panda, M. Manikandan, Shreyas P. Vaidya, Sushanta Chhatar, Suman Sinha, Megha Mehrotra, Sourav Chakraborty, Shubhankar Gadre, Prakash Duari, Pritha Ray, Malay Patra
Summary: Even in the era of precision medicine and immunotherapy, chemotherapy with platinum drugs is still widely used against various cancers. However, the efficacy of these drugs is limited by resistance and toxicity. In this study, we designed kinetically inert organometallic platinum anticancer agents with a novel mechanism of action. Our best candidate showed promising antitumor efficacy and could mitigate nephrotoxicity associated with cisplatin. This study demonstrates the importance of kinetic inertness in improving the therapeutic benefits of platinum-based anticancer therapy.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Biochemistry & Molecular Biology
Jianfeng Zhou, Liangzhe Wang, Wenjian Gong, Bo Wang, Deng-Guang Yu, Yuanjie Zhu
Summary: In this study, advanced micro-nanomanufacturing technologies and composite micro-nanostructures were used to develop a new type of pharmaceutical formulation with rapid hemostasis, pain relief, and antimicrobial properties. A novel beaded nanofiber structure (BNS) was fabricated using electrohydrodynamic atomization (EHDA) technique and reversed-phase solvent. The integration of Chinese herbs and Western medicine in this study provides valuable insights for the development of novel multiscale functional micro-/nano-composite materials and pioneers the developments of new types of medicines.
Article
Public, Environmental & Occupational Health
Ying Jin, Younhee Kim
Summary: This study compares the differences in dietary advice-giving between Traditional Chinese Medicine and Western Medicine practices for patients with chronic conditions. The findings show that Traditional Chinese Medicine doctors incorporate dietary advice into treatment recommendations and discuss it with patients, while Western Medicine doctors consider it less important and only use it for diagnostic assessment. These differences can be attributed to clinical pathology.
SOCIAL SCIENCE & MEDICINE
(2022)
Review
Biochemistry & Molecular Biology
Jaewan Jeon, Sungmin Lee, Hyunwoo Kim, Hyunkoo Kang, HyeSook Youn, Sunmi Jo, BuHyun Youn, Hae Yu Kim
Summary: This article discusses the anticancer effects and advantages of platinum-based drugs used in the treatment of brain tumors, and summarizes their clinical application cases and limitations. To overcome these obstacles, a novel approach to enhance the effectiveness of platinum-based drugs is emphasized.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
