Article
Biochemistry & Molecular Biology
Zhaoqian Fan, Yukun Qin, Song Liu, Ronge Xing, Huahua Yu, Kecheng Li, Pengcheng Li
Summary: In this study, a new chitosan oligosaccharide derivative was synthesized and evaluated for its nematocidal activity and mode of action against root-knot nematode. The derivative exhibited high activity against the nematode and inhibited egg hatching at low concentration. It was found to disrupt the nematode's ROS metabolism and cause damage to its intestinal tissue.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Jiang Zhan, Yukun Qin, Kun Gao, Zhaoqian Fan, Linsong Wang, Ronge Xing, Song Liu, Pengcheng Li
Summary: The study found that 6-oxychitin is a better promoter of the nematicidal potential of Purpureocillium lilacinum than other water-soluble chitin derivatives, inhibiting the movement and egg hatching of nematodes, destroying their accumulation and invasion, and promoting plant growth.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Plant Sciences
Ting Yang, Yi Xin, Tongyao Liu, Zhengfeng Li, Xingzhong Liu, Yunpeng Wu, Mingfeng Wang, Meichun Xiang
Summary: This study identified a rhizosphere bacterium, strain NC1, which showed strong inhibition against root-knot nematodes. Gas chromatography-mass spectrometry analysis revealed that the strain produced volatile compounds, DMDS and benzaldehyde, that exhibited nematicidal activity. A greenhouse trial demonstrated that the strain effectively controlled root-knot nematodes.
Article
Plant Sciences
Ke Liu, Caroline Eberlein, Abdelhossein Edalati, Ruihong Zhang, Andreas Westphal
Summary: Management of plant-parasitic nematodes encompasses various methods such as host plant resistance, crop rotation, cultural methods, and nematicide applications. However, the development of host resistance is laborious, while crop rotation and cultural methods present challenges. Sole reliance on chemical nematode suppression is not sustainable due to environmental and health concerns. Recent experiments have demonstrated that certain digestates possess nematode-suppressive capacity.
Article
Plant Sciences
Valdeir Junio Vaz Moreira, Isabela Tristan Lourenco-Tessutti, Marcos Fernando Basso, Maria Eugenia Lisei-de-Sa, Carolina Vianna Morgante, Bruno Paes-de-Melo, Fabricio Barbosa Monteiro Arraes, Diogo Martins-de-Sa, Maria Cristina Mattar Silva, Janice de Almeida Engler, Maria Fatima Grossi-de-Sa
Summary: This study successfully downregulated the expression of the Minc03328 effector gene during nematode parasitism using in planta RNA interference strategy, significantly reducing plant susceptibility to Meloidogyne incognita. The results confirm the importance of the Minc03328 gene in parasitism and demonstrate the potential for developing crop species that can efficiently control RKN.
Article
Agriculture, Multidisciplinary
Pornthip Ruanpanun, Prakit Somta
Summary: This study identified seven Vigna genotypes resistant to root-knot nematodes, with JP229392 and AusTRCF322090 showing the strongest resistance. The resistance in these genotypes appeared to be related to antibiosis, which could reduce nematode penetration, retard nematode development, and impede giant cell formation. The Vigna germplasm resistance to root-knot nematodes identified in this study could be utilized as gene sources for the development of resistant cultivars.
JOURNAL OF INTEGRATIVE AGRICULTURE
(2021)
Article
Cell Biology
Rahim Hassanaly-Goulamhoussen, Ronaldo De Carvalho Augusto, Nathalie Marteu-Garello, Arthur Pere, Bruno Favery, Martine Da Rocha, Etienne G. J. Danchin, Pierre Abad, Christoph Grunau, Laetitia Perfus-Barbeoch
Summary: The root-knot nematode Meloidogyne incognita adapts rapidly to unfavorable conditions through epigenetic mechanisms, impacting gene expression and sharing similar epigenetic signatures with the model nematode Caenorhabditis elegans. The H3K4me3 histone modification is strongly correlated with high expression of genes during specific developmental stages, providing insights into the dynamic regulation of parasitism genes.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Plant Sciences
Pasqua Veronico, Nicola Sasanelli, Alberto Troccoli, Arben Myrta, Audun Midthassel, Tariq Butt
Summary: Fungal volatile organic compounds (VOCs), particularly 1-Octen-3-ol, are highly toxic to root-knot nematodes and show potential as ecofriendly alternatives to synthetic nematicides. Exposure to 1-Octen-3-ol and 3-Octanone resulted in high mortality rates of the nematodes, with 1-Octen-3-ol exhibiting greater nematicidal activity than 3-Octanone.
Article
Plant Sciences
Trifone D'Addabbo, Aldo Tava, Maria Pia Argentieri, Elisa Biazzi, Vincenzo Candido, Pinarosa Avato
Summary: This study investigated the biocidal activity of flavonoids and tannins in sulla, as well as the suppressive effects of sulla biomass on the root-knot nematode. Results showed that flavonoids and tannins in sulla have the potential to kill nematodes, and soil amendment with sulla biomass can effectively reduce nematode densities on tomato roots and in the soil.
Article
Multidisciplinary Sciences
Ritul Saharan, J. A. Patil, Saroj Yadav, Anil Kumar, Vinod Goyal
Summary: The root-knot nematode is a damaging pest in vegetable crops globally. The continuous use of nematicide has negative impacts on human and environmental health. To reduce nematicide usage, eco-friendly integrated nematode management is necessary. Trichoderma, an antagonistic fungus, has shown efficacy in controlling root-knot nematode. The strain Trichoderma asperellum FbMi6 exhibited significant nematicidal activity and when enriched in neem cake, it increased okra yield and decreased nematode population.
SCIENTIFIC REPORTS
(2023)
Article
Plant Sciences
Anzhela M. Asaturova, Ludmila N. Bugaeva, Anna I. Homyak, Galina A. Slobodyanyuk, Evgeninya V. Kashutina, Larisa V. Yasyuk, Nikita M. Sidorov, Vladimir D. Nadykta, Alexey V. Garkovenko
Summary: In this study, two Bacillus strains were evaluated as promising agents for protecting cucumber plants from root-knot nematodes. The nematicidal activity of these strains was demonstrated, and their application was found to improve plant health and productivity.
Article
Agriculture, Multidisciplinary
Sydney Mwamba, Ruth Kihika-Opanda, Lucy K. Murungi, Turoop Losenge, John J. Beck, Baldwyn Torto
Summary: The study found that the root volatiles of non-host plants such as black-jack, marigold, and sweet wormwood contain (E)-beta-farnesene and 1,8-cineole, which have repellent effects on plant parasitic nematodes. In contrast, camphor was found to be attractive to the nematodes. Terpenoids in the root volatiles of non-host Asteraceae plants are generally responsible for their repellency towards PPNs.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Plant Sciences
Shixiao Xu, Pei Tian, Zhimin Jiang, Xiaoxiang Chen, Bo Li, Jutao Sun, Zhiqiang Zhang
Summary: In this study, the transcriptional dynamics and metabolic processes involved in the interaction between RKN-resistant and RKN-susceptible tobacco varieties infected with PVY MSNR were investigated using RNA-seq analysis and functional enrichment analysis. The results revealed significant differences in gene expression and metabolic pathways, providing insights into the resistance mechanisms of tobacco against PVY MSNR.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Ibrahim M. A. Gohar, Amal Alyamani, Manal E. Shafi, Elshaimaa A. E. Mohamed, Rehab Y. Ghareeb, Elsayed M. Desoky, Mohamed E. Hasan, Amera F. Zaitoun, Nader R. Abdelsalam, Khaled A. El-Tarabily, Ahmed S. M. Elnahal
Summary: This study investigated the susceptibility of eight sugar beet genotypes to the root-knot nematode. The genotypes were divided into four categories based on their resistance levels. The results showed significant differences in disease severity, yield production, and quality traits among the genotypes. Additionally, five single nucleotide polymorphisms were identified.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biotechnology & Applied Microbiology
Eun-Jae Park, Hyun-Jae Jang, Ji-Yeon Park, Ye Kyeong Yang, Min Ji Kim, Chan Sun Park, Soyoung Lee, Bong-Sik Yun, Seung-Jae Lee, Seung Woong Lee, Mun-Chual Rho
Summary: The nematicidal effects of Streptomyces nigrescens KA-1 were evaluated against Meloidogyne incognita, and it showed significant activity both in vitro and in vivo. Two active compounds, trichostatin C and dehydroxytrichostatin A, were isolated from the culture broth of the strain and exhibited potent anti-nematicidal activity.
BIOLOGICAL CONTROL
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)