Depletion of DNA damage binding protein 2 sensitizes triple‐negative breast cancer cells to poly ADP‐ribose polymerase inhibition by destabilizing Rad51

Update on PARP Inhibitors in Breast Cancer

(2018) Alexandra S. Zimmer et al.   CURRENT TREATMENT OPTIONS IN ONCOLOGY

β1-Integrin Impacts Rad51 Stability and DNA Double-Strand Break Repair by Homologous Recombination

(2018) Kazi Mokim Ahmed et al.   MOLECULAR AND CELLULAR BIOLOGY

PARP inhibitors: Synthetic lethality in the clinic

(2017) Christopher J. Lord et al.   SCIENCE

The Error-Prone DNA Polymerase κ Promotes Temozolomide Resistance in Glioblastoma through Rad17-Dependent Activation of ATR-Chk1 Signaling

(2016) Chenghao Peng et al.   CANCER RESEARCH

A phosphorylation–deubiquitination cascade regulates the BRCA2–RAD51 axis in homologous recombination

(2016) Kuntian Luo et al.   GENES & DEVELOPMENT

DDB2 increases radioresistance of NSCLC cells by enhancing DNA damage responses

(2016) Ning Zou et al.   TUMOR BIOLOGY

Promotion of RAD51-Mediated Homologous DNA Pairing by the RAD51AP1-UAF1 Complex

(2016) Fengshan Liang et al.   Cell Reports

FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51

(2015) Wai Kit Chu et al.   Nature Communications

New Strategies for Triple-Negative Breast Cancer--Deciphering the Heterogeneity

(2014) I. A. Mayer et al.   CLINICAL CANCER RESEARCH

Multiple Regulation of Rad51-Mediated Homologous Recombination by Fission Yeast Fbh1

(2014) Yasuhiro Tsutsui et al.   PLoS Genetics

DDB2: A Novel Regulator of NF- B and Breast Tumor Invasion

(2013) M. Ennen et al.   CANCER RESEARCH

DDB2 Suppresses Epithelial-to-Mesenchymal Transition in Colon Cancer

(2013) N. Roy et al.   CANCER RESEARCH

DNA Damage-Binding Complex Recruits HDAC1 to Repress Bcl-2 Transcription in Human Ovarian Cancer Cells

(2013) Ran Zhao et al.   MOLECULAR CANCER RESEARCH

Investigation of Radiation-induced Transcriptome Profile of Radioresistant Non-small Cell Lung Cancer A549 Cells Using RNA-seq

(2013) Hee Jung Yang et al.   PLoS One

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

(2012) J. Murai et al.   CANCER RESEARCH

On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1

(2012) X. Luo et al.   GENES & DEVELOPMENT

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Tumor Growth Inhibition by Olaparib in BRCA2 Germline-Mutated Patient-Derived Ovarian Cancer Tissue Xenografts

(2010) U. Kortmann et al.   CLINICAL CANCER RESEARCH

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

(2010) Andrew Tutt et al.   LANCET

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

(2010) M William Audeh et al.   LANCET

A Postincision-Deficient TFIIH Causes Replication Fork Breakage and Uncovers Alternative Rad51- or Pol32-Mediated Restart Mechanisms

(2010) María Moriel-Carretero et al.   MOLECULAR CELL

Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis

(2009) Bassant M. Barakat et al.   INTERNATIONAL JOURNAL OF CANCER

DDB2 decides cell fate following DNA damage

(2009) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SUMO Modification Regulates BLM and RAD51 Interaction at Damaged Replication Forks

(2009) Karen J. Ouyang et al.   PLOS BIOLOGY

Selective Inhibition of BRCA2-Deficient Mammary Tumor Cell Growth by AZD2281 and Cisplatin

(2008) B. Evers et al.   CLINICAL CANCER RESEARCH

4-[3-(4-Cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: A Novel Bioavailable Inhibitor of Poly(ADP-ribose) Polymerase-1

(2008) Keith A. Menear et al.   JOURNAL OF MEDICINAL CHEMISTRY

Damaged DNA Binding Protein 2 Plays a Role in Breast Cancer Cell Growth

(2008) Zilal Kattan et al.   PLoS One

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs

(2008) S. Rottenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA