ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms

EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases

(2019) Noé Vázquez et al.   Interdisciplinary Sciences-Computational Life Sciences

ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism

(2018) Maxime W.C. Rousseaux et al.   NEURON

PolyQ Tract Toxicity in SCA1 is Length Dependent in the Absence of CAG Repeat Interruption

(2018) Suran Nethisinghe et al.   Frontiers in Cellular Neuroscience

Disruption of the ATXN1–CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans

(2017) Hsiang-Chih Lu et al.   NATURE GENETICS

Polyglutamine spinocerebellar ataxias — from genes to potential treatments

(2017) Henry L. Paulson et al.   NATURE REVIEWS NEUROSCIENCE

The Protein Structure Context of PolyQ Regions

(2017) Franziska Totzeck et al.   PLoS One

No effect ofARpolyG polymorphism on spinal and bulbar muscular atrophy phenotype

(2016) C. Bertolin et al.   EUROPEAN JOURNAL OF NEUROLOGY

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes

(2016) G.C.P. van Zundert et al.   JOURNAL OF MOLECULAR BIOLOGY

PANTHER version 11: expanded annotation data from Gene Ontology and Reactome pathways, and data analysis tool enhancements

(2016) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

A key lysine residue in the AXH domain of ataxin-1 is essential for its ubiquitylation

(2015) A-ram Kang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

(2015) Fabian Hosp et al.   Cell Reports

Differential Occurrence of Interactions and Interaction Domains in Proteins Containing Homopolymeric Amino Acid Repeats

(2015) Ilaria Pelassa et al.   Frontiers in Genetics

Polyglutamine (PolyQ) Diseases: Genetics to Treatments

(2014) Hueng-Chuen Fan et al.   CELL TRANSPLANTATION

Beyond the Glutamine Expansion: Influence of Posttranslational Modifications of Ataxin-1 in the Pathogenesis of Spinocerebellar Ataxia Type 1

(2014) Hyoungseok Ju et al.   MOLECULAR NEUROBIOLOGY

Kaleidoscopic protein–protein interactions in the life and death of ataxin-1: new strategies against protein aggregation

(2014) Cesira de Chiara et al.   TRENDS IN NEUROSCIENCES

Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners

(2013) Spyros Petrakis et al.   BIOESSAYS

Self-Assembly and Conformational Heterogeneity of the AXH Domain of Ataxin-1: An Unusual Example of a Chameleon Fold

(2013) Cesira de Chiara et al.   BIOPHYSICAL JOURNAL

Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua

(2013) E. Kim et al.   GENES & DEVELOPMENT

An Out-of-frame Overlapping Reading Frame in the Ataxin-1 Coding Sequence Encodes a Novel Ataxin-1 Interacting Protein

(2013) Danny Bergeron et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein-Protein Interactions as a Strategy towards Protein-Specific Drug Design: The Example of Ataxin-1

(2013) Cesira de Chiara et al.   PLoS One

Mechanisms of RNA-induced toxicity in CAG repeat disorders

(2013) R Nalavade et al.   Cell Death & Disease

Development and application of a DNA microarray-based yeast two-hybrid system

(2012) Bernhard Suter et al.   NUCLEIC ACIDS RESEARCH

Evolution and function of CAG/polyglutamine repeats in protein–protein interaction networks

(2012) Martin H. Schaefer et al.   NUCLEIC ACIDS RESEARCH

ATXN1 Protein Family and CIC Regulate Extracellular Matrix Remodeling and Lung Alveolarization

(2011) Yoontae Lee et al.   DEVELOPMENTAL CELL

Ataxin-1 and Brother of ataxin-1 are components of the Notch signalling pathway

(2011) Xin Tong et al.   EMBO REPORTS

CPORT: A Consensus Interface Predictor and Its Performance in Prediction-Driven Docking with HADDOCK

(2011) Sjoerd J. de Vries et al.   PLoS One

Essential Role of Coiled Coils for Aggregation and Activity of Q/N-Rich Prions and PolyQ Proteins

(2010) Ferdinando Fiumara et al.   CELL

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

(2010) Edward L. Huttlin et al.   CELL

Conformational Diseases: Structural Studies of Aggregation of Polyglutamine Proteins

(2010) Elena Papaleo et al.   Current Computer-Aided Drug Design

The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

(2009) Raphael Kopan et al.   CELL

Examining Polyglutamine Peptide Length: A Connection between Collapsed Conformations and Increased Aggregation

(2009) Robert H. Walters et al.   JOURNAL OF MOLECULAR BIOLOGY

Molecular pathogenesis of spinocerebellar ataxia type 1 disease

(2009) Seongman Kang et al.   MOLECULES AND CELLS

Pathogenic Mechanisms of a Polyglutamine-mediated Neurodegenerative Disease, Spinocerebellar Ataxia Type 1

(2008) Huda Y. Zoghbi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Consequences of poly-glutamine repeat length for the conformation and folding of the androgen receptor amino-terminal domain

(2008) Philippa Davies et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

(2008) Janghoo Lim et al.   NATURE