Epigenetic landscapes suggest that genetic risk for intracranial aneurysm operates on the endothelium

Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm–Associated Regions to Potential Candidate Genes

(2019) Melanie D. Laarman et al.   Journal of the American Heart Association

Circulating neutrophil transcriptome may reveal intracranial aneurysm signature

(2018) Vincent M. Tutino et al.   PLoS One

Intracranial Aneurysm–Associated Single-Nucleotide Polymorphisms Alter Regulatory DNA in the Human Circle of Willis

(2018) Melanie D. Laarman et al.   STROKE

Using Chromatin Architecture to Understand the Genetics and Transcriptomics of Juvenile Idiopathic Arthritis

(2018) Haeja Kessler et al.   Frontiers in Immunology

DNA Methylation Regulates Gene Expression in Intracranial Aneurysms

(2017) Lanbing Yu et al.   World Neurosurgery

Prevalence of Intracranial Aneurysms in Patients with Connective Tissue Diseases: A Retrospective Study

(2016) S. T. Kim et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

MicroRNA and gene expression changes in unruptured human cerebral aneurysms

(2016) Kimon Bekelis et al.   JOURNAL OF NEUROSURGERY

Role of non-coding RNA transcription around gene regulatory elements in transcription factor recruitment

(2016) Naomichi Takemata et al.   RNA Biology

Exonic enhancers: proceed with caution in exome and genome sequencing studies

(2016) Nadav Ahituv   Genome Medicine

Myeloperoxidase Is Increased in Human Cerebral Aneurysms and Increases Formation and Rupture of Cerebral Aneurysms in Mice

(2015) Yi Chu et al.   STROKE

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

(2015) Paul Martin et al.   Nature Communications

Endothelial Cells Expressing Endothelial and Mesenchymal Cell Gene Products in Lung Tissue From Patients With Systemic Sclerosis-Associated Interstitial Lung Disease

(2015) Fabian A. Mendoza et al.   Arthritis & Rheumatology

Disease-Associated Single-Nucleotide Polymorphisms From Noncoding Regions in Juvenile Idiopathic Arthritis Are Located Within or Adjacent to Functional Genomic Elements of Human Neutrophils and CD4+ T Cells

(2015) Kaiyu Jiang et al.   Arthritis & Rheumatology

Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal

(2015) Patrícia Abrantes et al.   PLoS One

Genome-wide microRNA changes in human intracranial aneurysms

(2014) Dehua Liu et al.   BMC Neurology

Versican and the control of inflammation

(2014) Thomas N. Wight et al.   MATRIX BIOLOGY

Genetic and epigenetic fine mapping of causal autoimmune disease variants

(2014) Kyle Kai-How Farh et al.   NATURE

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Gene Expression Profiling Reveals Distinct Molecular Signatures Associated With the Rupture of Intracranial Aneurysm

(2014) Hirofumi Nakaoka et al.   STROKE

Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7

(2014) Tatiana Foroud et al.   STROKE

High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms

(2014) Mitja I. Kurki et al.   PLoS Genetics

High WSS or Low WSS? Complex Interactions of Hemodynamics with Intracranial Aneurysm Initiation, Growth, and Rupture: Toward a Unifying Hypothesis

(2013) H. Meng et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Epidemiology and genetics of intracranial aneurysms

(2013) F. Caranci et al.   EUROPEAN JOURNAL OF RADIOLOGY

Gene Expression Profiling of Blood in Ruptured Intracranial Aneurysms: in Search of Biomarkers

(2013) Joanna Pera et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Circulating microRNA: a novel potential biomarker for early diagnosis of Intracranial Aneurysm Rupture a case control study

(2013) Hengwei Jin et al.   Journal of Translational Medicine

Genetic risk factors for intracranial aneurysms: A meta-analysis in more than 116,000 individuals

(2013) V. S. Alg et al.   NEUROLOGY

Inflammation and Cerebral Aneurysms

(2013) Koji Hosaka et al.   Translational Stroke Research

Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice

(2013) Kyung Ho Kim et al.   Jove-Journal of Visualized Experiments

Saccular intracranial aneurysm: pathology and mechanisms

(2012) Juhana Frösen et al.   ACTA NEUROPATHOLOGICA

Multiple Roles for Neutrophils in Atherosclerosis

(2012) Oliver Soehnlein   CIRCULATION RESEARCH

Linking disease associations with regulatory information in the human genome

(2012) M. A. Schaub et al.   GENOME RESEARCH

Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA

(2012) Siew-Kee Low et al.   HUMAN MOLECULAR GENETICS

Macrophage imbalance (M1 vs. M2) and upregulation of mast cells in wall of ruptured human cerebral aneurysms: preliminary results

(2012) David Hasan et al.   Journal of Neuroinflammation

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk

(2012) Tatiana Foroud et al.   STROKE

Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions

(2011) Gabriel E. Zentner et al.   GENOME RESEARCH

Common variant near the endothelin receptor type A (EDNRA) gene is associated with intracranial aneurysm risk

(2011) K. Yasuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Association between genetic variation on chromosome 9p21 and aneurysmal subarachnoid haemorrhage

(2010) S. Olsson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Genome-wide association study of intracranial aneurysm identifies three new risk loci

(2010) Katsuhito Yasuno et al.   NATURE GENETICS

Annotating non-coding regions of the genome

(2010) Roger P. Alexander et al.   NATURE REVIEWS GENETICS

The Relationship Between Smoking and Replicated Sequence Variants on Chromosomes 8 and 9 With Familial Intracranial Aneurysm

(2010) Ranjan Deka et al.   STROKE

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

The genetics of sporadic ruptured and unruptured intracranial aneurysms: a genetic meta-analysis of 8 genes and 13 polymorphisms in approximately 20,000 individuals

(2009) Peter McColgan et al.   JOURNAL OF NEUROSURGERY

The critical role of hemodynamics in the development of cerebral vascular disease

(2009) Alexander M. Nixon et al.   JOURNAL OF NEUROSURGERY

Cathepsin G-Mediated Activation of Pro-Matrix Metalloproteinase 9 at the Tumor-Bone Interface Promotes Transforming Growth Factor-  Signaling and Bone Destruction

(2009) T. J. Wilson et al.   MOLECULAR CANCER RESEARCH

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Genomics of Human Intracranial Aneurysm Wall

(2009) Changbin Shi et al.   STROKE

Intracranial and Abdominal Aortic Aneurysms: Similarities, Differences, and Need for a New Class of Computational Models

(2008) J.D. Humphrey et al.   Annual Review of Biomedical Engineering

Protein Phosphatase 6 Regulatory Subunits Composed of Ankyrin Repeat Domains†

(2008) Bjarki Stefansson et al.   BIOCHEMISTRY

SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap

(2008) A. D. Johnson et al.   BIOINFORMATICS

Proteolytic Activation of Matrix Metalloproteinase-9 in Skin Wound Healing Is Inhibited by α-1-Antichymotrypsin

(2008) Yuan-Ping Han et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Neutrophil and Monocyte CD64 and CD163 Expression in Critically Ill Neonates and Children with Sepsis: Comparison of Fluorescence Intensities and Calculated Indexes

(2008) Mojca Groselj-Grenc et al.   MEDIATORS OF INFLAMMATION

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm

(2008) Anna Helgadottir et al.   NATURE GENETICS

Susceptibility loci for intracranial aneurysm in European and Japanese populations

(2008) Kaya Bilguvar et al.   NATURE GENETICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH