期刊
BIOINFORMATICS
卷 32, 期 22, 页码 3380-3387出版社
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btw493
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- St. Petersburg State University, St. Petersburg, Russia [15.61.951.2015]
Motivation: Plasmids are stably maintained extra-chromosomal genetic elements that replicate independently from the host cell's chromosomes. Although plasmids harbor biomedically important genes, (such as genes involved in virulence and antibiotics resistance), there is a shortage of specialized software tools for extracting and assembling plasmid data from whole genome sequencing projects. Results: We present the plasmidSPAdes algorithm and software tool for assembling plasmids from whole genome sequencing data and benchmark its performance on a diverse set of bacterial genomes.
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