Article
Pediatrics
I. M. Davies, K. J. Crossley, E. V. Mcgillick, I. Nitsos, K. Rodgers, A. Thiel, V. A. Zahra, A. B. te Pas, S. B. Hooper
Summary: The study investigates the breathing patterns of newborn lambs and finds that there is significant heterogeneity in respiratory patterns during the immediate newborn period, which also change with time. This study provides insight into respiratory behaviors that may indicate respiratory distress in full-term newborn infants.
FRONTIERS IN PEDIATRICS
(2023)
Article
Microbiology
Noel T. Mueller, Moira K. Differding, Haipeng Sun, Jincheng Wang, Shira Levy, Varsha Deopujari, Lawrence J. Appel, Martin J. Blaser, Tanima Kundu, Ankit A. Shah, Maria Gloria Dominguez Bello, Suchitra K. Hourigan
Summary: Children delivered by elective C-section are not exposed to the birth canal and have altered microbiota development, which can affect their metabolic and immune programming and increase the risk of immune and metabolic diseases. Vaginal seeding can increase the transmission of maternal microbiota to neonates and cause changes in the composition and diversity of their skin and stool microbiota.
Article
Infectious Diseases
Thor Haahr, Tine Dalsgaard Clausen, Jonathan Thorsen, Morten A. Rasmussen, Martin S. Mortensen, Jenni Lehtimaki, Shiraz A. Shah, Mathis H. Hjelmso, Klaus Bonnelykke, Bo L. Chawes, Gisle Vestergaard, Bo Jacobsson, Per-Goran Larsson, Susanne Brix, Soren J. Sorensen, Hans Bisgaard, Jakob Stokholm
Summary: The study found that changes in vaginal microbiota during pregnancy correlated with bacterial vaginosis status and vaginal community state type. A novel vaginal dysbiosis score was developed and found to be significantly associated with an increased risk of emergency cesarean section.
CLINICAL MICROBIOLOGY AND INFECTION
(2022)
Article
Veterinary Sciences
Leticia Lima de Almeida, Renata Azevedo de Abreu, Maira Morales Brito, Thayna Pantoja Gardes, Renato Bueno Flores, Roberto Rodrigues da Rosa Filho, Camila Infantosi Vannucchi
Summary: This study found that puppies born by c-section had lower oxygen saturation at birth and 1 hour, as well as higher protein oxidation compared to those born by vaginal delivery. Vaginally delivered puppies had higher TBARS levels, while c-section puppies had higher GPx activity. Additionally, SOD decreased in c-section puppies within 72 hours. Overall, c-section may result in puppies being less exposed to the negative consequences of oxidative stress.
Article
Medicine, General & Internal
Brooke C. Wilson, Eadaoin M. Butler, Celia P. Grigg, Jose G. B. Derraik, Valentina Chiavaroli, Nicholas Walker, Suma Thampi, Christine Creagh, Abigail J. Reynolds, Tommi Vatanen, Justin M. O'Sullivan, Wayne S. Cutfield
Summary: Oral administration of maternal vaginal microbiota did not alter gut microbiome development in infants born by caesarean section; limited colonisation of maternal vaginal strains suggests other maternal sources, such as the perianal area, may play a larger role in seeding the neonatal gut microbiome.
Editorial Material
Microbiology
Suchitra K. Hourigan, Maria Gloria Dominguez-Bello, Noel T. Mueller
Summary: This article discusses the importance of maternal-child microbial seeding interventions for C-section delivered infants and the potential impact on immune development and inflammatory conditions.
CELL HOST & MICROBE
(2022)
Article
Neurosciences
Timothy G. Dinan, Paul J. Kennedy, Livia H. Morais, Amy Murphy, Caitriona M. Long-Smith, Gerard M. Moloney, Thomaz F. S. Bastiaanssen, Andrew P. Allen, Aoife Collery, David Mullins, Anne-Marie Cusack, Kirsten Berding, Paul W. O'Toole, Gerard Clarke, Catherine Stanton, John F. Cryan
Summary: Birth by C-section has enduring effects on psychological processes in humans. Young adults born by C-section exhibit increased psychological vulnerability to acute stress and a prolonged period of stress. However, the effects on cognitive ability and gut microbiota are minimal.
NEUROBIOLOGY OF STRESS
(2022)
Article
Microbiology
Xing Yang, Xinyi Pan, Manchao Li, Zhi Zeng, Yanxian Guo, Panyu Chen, Xiaoyan Liang, Peigen Chen, Guihua Liu
Summary: This study revealed the adverse effects of potentially harmful microbes on the host endometrium in Cesarean section scar diverticulum (CSD). The mechanism of these effects includes inhibition of beneficial bacteria activity such as lactobacilli, consumption of protective endometrium metabolites, and production of harmful metabolites. From the perspectives of microbial, metabolic, and host responses, this study provides important insights to design preventive and therapeutic strategies for CSD.
MICROBIOLOGY SPECTRUM
(2022)
Article
Obstetrics & Gynecology
Eadaoin M. Butler, Abigail J. Reynolds, Jose G. B. Derraik, Brooke C. Wilson, Wayne S. Cutfield, Celia P. Grigg
Summary: The study found that some pregnant women consider vaginal seeding as a way to replicate a natural process, believing it has potential benefits and can help reduce guilt associated with cesarean section. Most pregnant women have a positive or neutral attitude towards vaginal seeding, but have limited knowledge about the practice.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Pediatrics
Delphine M. Hoang, Elvira I. Levy, Yvan Vandenplas
Summary: Cesarean section can lead to dysbiosis of the infant gut microbiome, potentially impacting infant health. While breastfeeding can help, other interventions like vaginal seeding and probiotics supplementation need further research to determine their effectiveness.
Article
Immunology
Jingxian Xie, Chen Tang, Shouqiang Hong, Yuntian Xin, Jie Zhang, Yi Lin, Lindong Mao, Yunshan Xiao, Quanfeng Wu, Xueqin Zhang, Heqing Shen
Summary: The composition of newborn gut microbiota is influenced by the mode of delivery. Newborns born by cesarean section with vaginal seeding have a gut microbiota composition more similar to newborns born vaginally.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2023)
Review
Medicine, General & Internal
Laxminarayan Karanth, Sachchithanantham Kanagasabai, Adinegara Bl Abas
Summary: Bleeding disorders in women may improve during pregnancy, reducing the risk of hemorrhage during delivery, but some disorders do not return to pre-pregnancy levels quickly postpartum. There is currently no high-quality evidence on the safest mode of delivery for women with bleeding disorders. Further research using controlled studies is needed to determine the optimal delivery method.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)
Article
Agriculture, Dairy & Animal Science
Karita da Mata Fuchs, Keylla Helena Nobre Pacifico Pereira, Gabriela Carneiro de Sousa, Gleice Mendes Xavier, Gabriel de Azevedo Camargo, Fabiana Ferreira de Souza, Maria Lucia Gomes Lourenco
Summary: A hypercaloric supplement containing vitamins and amino acids can be used as an alternative to glucose in hypoglycaemic puppies, providing nutritional benefits. Prepartum glycaemia of the dam is an important parameter to be measured and proper management can reduce the risk of puppies being born with hypoglycaemia.
REPRODUCTION IN DOMESTIC ANIMALS
(2023)
Article
Medicine, General & Internal
Hester Chang Qi Lau, Michelle E-Jyn Kwek, Ilka Tan, Manisha Mathur, Ann Wright
Summary: The study evaluated the effectiveness of two scoring systems in predicting VBAC success in Singapore, with the Kalok scoring system (AUC 0.740) outperforming the Grobman nomogram (AUC 0.664). Patient's age, body mass index at booking, and history of successful VBAC were identified as important factors in predicting VBAC success.
ANNALS ACADEMY OF MEDICINE SINGAPORE
(2021)
Article
Obstetrics & Gynecology
Philip Hepp, Markus Fleisch, Kathrin Hasselbach, Tanja Fehm, Nora K. Schaal
Summary: Evidence shows that music has positive effects on patients and healthcare professionals in various medical scenarios. A study in Germany surveyed obstetricians and midwives, discovering that while music is more commonly played during vaginal births, there is a lack of equipment for music in operation theatres where caesarean sections take place. The majority of respondents believe that music is beneficial for team communication and patient communication.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2021)
