Article
Chemistry, Analytical
Lijun Lin, Yanjun Jiang, Yin Chen, Lei Ji, Mingyao Xu, Yuanjian Liu, Xiaohui Xiong
Summary: This study reports a visual electrochemiluminescence (ECL) sensing platform based on a double bipolar electrode (D-BPE) for the detection of organophosphorus pesticides (OPPs). The ECL signal at one electrode was enhanced due to the enzymatic reaction occurring at another electrode. The addition of OPPs inhibited the enzymatic reaction, resulting in a weakened ECL signal. This method offers a fast and easy detection of OPPs.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Yi-Lei Jia, Cong-Hui Xu, Xiao-Qiong Li, Hong-Yuan Chen, Jing-Juan Xu
Summary: By combining a closed bipolar electrode (BPE) chip with multicolor electrochemiluminescence (ECL) imaging technology, a low-voltage driven portable visualized ECL device was constructed for the early screening of Alzheimer's disease (AD). This device showed good reproducibility and high sensitivity, with a detection limit of 1 pM by naked eye. It provides a promising point-of-care testing (POCT) tool for the screening of Alzheimer's-related diseases in the early stage.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Mingyao Xu, Yin Chen, Yunjie Fei, Fenglan Lv, Xiaohui Xiong, Yuanjian Liu
Summary: A bipolar electrode electrochemiluminescence (BPE-ECL) with beta-cyclodextrin (beta-CD) host-guest recognition was constructed for the rapid detection of Salmonella typhimurium (S. typhimurium). The method utilizes specific binding and spatial matching principles to convert the electrochemical signal into a luminescent signal for quantitative detection of S. typhimurium.
MICROCHEMICAL JOURNAL
(2023)
Article
Food Science & Technology
Qin Tao, Ning Tang, Songtao OuYang, Yanjun Jiang, Yun Luo, Yuanjian Liu, Xiaohui Xiong
Summary: A multicolor electrochemiluminescence (ECL) apparatus based on a closed bipolar electrode (BPE) system was proposed for the visual testing of Ochratoxin A (OTA). The presence of OTA was reflected by target-induced elimination of the Fc-aptamer from the cathode pole, leading to a reduction in the current of the BPE and a color change on the anode electrode. The device holds great potential in the rapid food safety testing.
FOOD ANALYTICAL METHODS
(2023)
Article
Biophysics
Bin Chen, Qin Tao, Songtao OuYang, Minhui Wang, Yuanjian Liu, Xiaohui Xiong, Songqin Liu
Summary: This study demonstrates that E. coli O157:H7 can electrochemically catalyze oxygen reduction at the cathode of bipolar electrode (BPE), resulting in electrochemiluminescence (ECL) reporting intensity change at the anode. Most food matrix does not exhibit catalytic activity for electrochemical reduction of O-2, and their interference with the ECL reaction at the anode is negligible. A low detection limit of 10 CFU mL(-1) for E. coli O157:H7 can be achieved within 1 hour using this system, making it an excellent tool for rapid detection of electroactive bacteria in food.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Yun Luo, Fenglan Lv, Minhui Wang, Lixia Lu, Yuanjian Liu, Xiaohui Xiong
Summary: The multicolor electrochemiluminescence (ECL) device based on closed bipolar electrode (BPE) allows for visualized sensing of Salmonella typhimurium (S. typhimurium). By modulating the resistance of BPE, bidirectional color change can be observed, which is attributed to the dual-potential excitation property of the concomitant electrochemiluminophores. This sensor has a low detection limit of 10 CFU mL-1 and can greatly shorten the experiment time without complex pre-enrichment bacterial. The electrochemical signal is converted into a more intuitive optical readout for visualized sensing of S. typhimurium in food, merging the sensitivity of electrochemistry with the intuitiveness of an optical readout.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Food Science & Technology
Fanglin Qiao, Yin Chen, Yunjie Fei, Yanjun Jiang, Xiaohui Xiong, Yuanjian Liu
Summary: In this study, a biosensor based on immune competition was designed using the advantages of closed bipolar electrode (BPE) to detect highly toxic aflatoxin B1 (AFB1). The biosensor exhibited high sensitivity and specificity in detecting AFB1 and showed promising application prospects in detecting other toxins.
FOOD ANALYTICAL METHODS
(2023)
Article
Engineering, Electrical & Electronic
Manish Bhaiyya, Prasant Kumar Pattnaik, Sanket Goel
Summary: A closed bipolar Electrochemiluminescence (LIG-C-BPE-ECL) system based on two and three-channel laser-induced graphene was developed for sensing various analytes. The system featured the use of polyimide sheet for fabrication and a portable 3D printed system to house the device and smartphone. Both two and three-channel LIG-C-BPE-ECL devices were successfully fabricated for individual and simultaneous detection of analytes, demonstrating potential for point of care testing in various applications.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Chemistry, Applied
Liangzhe Wang, Jiadi Sun, Jin Ye, Liping Wang, Xiulan Sun
Summary: This study successfully developed a method based on time-resolved fluorescence microsphere-immunochromatographic test strip for rapid, accurate, and sensitive detection of AFB(1) and Cd in grains. The research showed that the method could achieve simultaneous detection of two pollutants in one extraction, and it has stable storage for at least 12 months.
Article
Chemistry, Analytical
Qi Wang, Fangyuan Zhao, Qingli Yang, Wei Wu
Summary: A fluorescence aptasensor based on DNA walker, DNA tetrahedron nanostructures, and network hybridization chain reaction was proposed for monitoring Aflatoxin B-1 (AFB(1)). The sensor could sensitively detect AFB(1) by utilizing a DNA walker as a signal amplifier and combining DTNs and HCR.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biochemical Research Methods
Veli Ziya Erdem, Hatice Imge Oktay Basegmez, Gozde Baydemir Pesint
Summary: In this study, PHEMA-based molecularly imprinted magnetic nanoparticles (magAFB1-MIPs) were synthesized for the selective recognition and removal of AFB1 from liver tissue.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2022)
Review
Chemistry, Analytical
Xin Zhang, Peilin Wang, Yixin Nie, Qiang Ma
Summary: In the field of electrochemiluminescence (ECL) sensing research, nano-scale organic emitters (NOEs) have demonstrated significant advantages including high luminescence efficiency, controllable emission, and various ECL properties. This paper provides a comprehensive overview of the development of NOEs as ECL emitters, discussing the different types of NOEs, their molecular structure, luminescence mechanisms, current ECL sensing strategies, and potential applications. Additionally, the limitations and potential value of NOEs for further advancement in ECL sensor technology are also reviewed.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Electrochemistry
Ping Zhou, Wenxuan Fu, Lurong Ding, Yajuan Yan, Weiliang Guo, Bin Su
Summary: This study investigated the mechanism of cathodic electrochemiluminescence (ECL) generation by tris(2,2'-bipyridyl)ruthenium (Ru(bpy)(3)(2+)) and S2O82-. The use of bismuth microwire electrode and ECL microscopy allowed for a better understanding of the reaction. Results showed that the thickness of the ECL layer varied slightly with increasing S2O82- concentration, possibly due to the instability of Ru(bpy)(3)(+) in aqueous solutions.
ELECTROCHIMICA ACTA
(2023)
Review
Chemistry, Physical
Fangxin Du, Yequan Chen, Chengda Meng, Baohua Lou, Wei Zhang, Guobao Xu
Summary: This review summarizes recent advances in ECL strategies with multiple-signal outputs, including ratiometric ECL, ECL multiplex immunoassay (MIA), and ECL imaging, discussing their signal generation strategies and applications in immunoassays. Challenges and prospects in this field are also addressed.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Article
Nanoscience & Nanotechnology
Manish Bhaiyya, Prasant Kumar Pattnaik, Sanket Goel
Summary: Vitamin B-12 plays a crucial role in human health, and its deficiency can lead to various health issues. The study successfully utilized ECL platforms for rapid and accurate detection of vitamin B-12 levels, ensuring the well-being of individuals.
MICROFLUIDICS AND NANOFLUIDICS
(2021)
Article
Food Science & Technology
Wei Yuan, Lixia Lu, Yichen Lu, Xiong Xiong, Yi Li, Xiaowen Cui, Yuanjian Liu, Xiaohui Xiong
Summary: This study proposed a synergistic strategy for detecting OTA in grains, combining DNA tetrahedron-structured aptamer (DTA) and hybridization chain reaction (HCR). The combination of DTA and HCR improved the recognition rate of OTA and allowed for the synthesis of a large amount of PANI under mild conditions, leading to effective OTA detection.
FOOD ANALYTICAL METHODS
(2021)
Article
Chemistry, Applied
Xiong Xiong, Wenjie Xu, Longqing Guo, Jiaxin An, Lilin Huang, Hanyong Qian, Xiaowen Cui, Yi Li, Min Cao, Xiaohui Xiong, Xiaoguo Ying, Libin Wang
Summary: The study developed a novel LAMP assay targeting skipjack tuna for rapid screening in processed fish products. Through primer optimization and specificity confirmation, the method showed high efficiency and sensitivity, detecting DNA levels as low as 50 pg.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Food Science & Technology
Wenjie Xu, Qiuping Li, Xiaowen Cui, Min Cao, Xiaohui Xiong, Libin Wang, Xiong Xiong
Summary: A novel LAMP assay coupled with a self-quenching fluorogenic probe was developed for rapid detection of skipjack tuna, achieving high sensitivity and tolerance, and successfully authenticating skipjack tuna from commercial tuna products.
FOOD ANALYTICAL METHODS
(2022)
Article
Chemistry, Applied
Li Qiuping, Cheng Yinghao, Xu Wenjie, Cui Xiaowen, Cao Min, Xiong Xiaohui, Wang Libin, Xiong Xiong
Summary: In this study, Loop-mediated isothermal amplification (LAMP) coupled with a self-quenching approach was developed for accurate species identification in fish. The novel assay showed high tolerance to impurities and produced reliable positive results under different DNA extraction methods and sample treatments. Additionally, using DNA with higher purity improved LAMP amplification.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Medicinal
Xiaohong Wang, Jianping Da, Yuanjian Liu
Summary: An electrochemical biosensor for staphylococcal enterotoxin B (SEB) detection has been designed based on the electrochemical interrogation of conformational changes, showing high sensitivity and accuracy.
Article
Chemistry, Applied
Bin Chen, Qin Tao, Fanglin Qiao, Yunjie Fei, Yuanjian Liu, Xiaohui Xiong, Songqin Liu
Summary: An Ag@C hybrid bipolar electrode sensing platform has been established for the detection of Staphylococcus aureus in food. This platform combines the advantages of anodic dissolution of Ag and cathodic biocatalysis of O-2 reduction, achieving an ultralow detection limit and quantification of S. aureus.
Article
Chemistry, Applied
Wenjie Xu, Qiuping Li, Hanyue Xue, Yanjin Fei, Xiaowen Cui, Min Cao, Xiaohui Xiong, Xiong Xiong, Ying Yang, Libin Wang
Summary: One major drawback to the traditional loop-mediated isothermal amplification (LAMP) detection methods is the increased likelihood of detecting false-positive signals derived from non-specific amplification. Molecular beacon (MB) is increasingly being used in many applications and the MB-LAMP assay has proved itself as a target specific method. The present work selected skipjack tuna as a case study, and developed a novel MB-LAMP assay for rapid species authentication. The assay demonstrated high specificity and could detect as little as 0.5 pg of skipjack tuna DNA.
Article
Biophysics
Bin Chen, Qin Tao, Songtao OuYang, Minhui Wang, Yuanjian Liu, Xiaohui Xiong, Songqin Liu
Summary: This study demonstrates that E. coli O157:H7 can electrochemically catalyze oxygen reduction at the cathode of bipolar electrode (BPE), resulting in electrochemiluminescence (ECL) reporting intensity change at the anode. Most food matrix does not exhibit catalytic activity for electrochemical reduction of O-2, and their interference with the ECL reaction at the anode is negligible. A low detection limit of 10 CFU mL(-1) for E. coli O157:H7 can be achieved within 1 hour using this system, making it an excellent tool for rapid detection of electroactive bacteria in food.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Applied
Yanjin Fei, Hanyue Xue, Xiong Xiong, Ying Yang, Libin Wang, Xiaohui Xiong
Summary: Using species outside Salmonidae for salmon products is a new type of fraud found in China and other countries with lenient labeling regulations. This study developed a mini-DNA barcoding assay to detect Salmonidae ingredient in processed fish products using the mitochondrial Cytb gene. The assay showed high specificity and successfully identified the seven common salmonid species. It also allowed accurate differentiation of species like Salar salar and Oncorhynchus mykiss, which are often mislabeled. The method is effective in screening Salmonidae ingredient in commercial products.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Applied
Yi Li, Hanyue Xue, Yanjing Fei, Ying Yang, Danping Huang, Libin Wang, Xiaohui Xiong, Xiong Xiong
Summary: To improve the suitability for naked-eye inspection, a strategy based on the fluorescence property of SYTO 9 and HNB was proposed, and a novel dual-color fluorescence LAMP (dfLAMP) assay was developed for visual detection of Atlantic salmon. The optimized dfLAMP assay has proved its specificity and can detect as little as 1 fg Atlantic salmon DNA.
Article
Biochemistry & Molecular Biology
Lili Yao, Tao Man, Xiong Xiong, Yicheng Wang, Xinxin Duan, Xiaohui Xiong
Summary: This study investigated the effects of cinnamon essential oil Pickering emulsions (CEOEs) using zein/carboxymethyl tamarind gum as stabilizers on the properties of Hydroxypropyl methyl cellulose (HPMC) films and their influence on cherry tomato shelf life. Results showed that the droplet size decreased with increasing degree of substitution, improving droplet distribution and film properties. Addition of CEOEs increased tensile strength and decreased water vapor permeability. The films also exhibited good UV barrier properties and improved antibacterial and antioxidant activities.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Agriculture, Multidisciplinary
Xue Hanyue, Fei Yanjin, Wang Shihui, Lili Yao, Xiong Xiong, Yang Ying
Summary: This study developed a novel loop-mediated isothermal amplification (LAMP) assay for Atlantic cod authentication. The assay demonstrated high specificity and applicability, capable of detecting as little as 1 pg of Atlantic cod DNA and detecting cod adulteration as low as 10%. No cross-reactivity was observed.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2023)
Article
Biophysics
Qin Tao, Ning Tang, Yanjun Jiang, Bin Chen, Yuanjian Liu, Xiaohui Xiong, Songqin Liu
Summary: A color-switch electrochemiluminescence (ECL) sensing platform based on a dual-bipolar electrode (D-BPE) is developed for sensitive detection of food-borne pathogenic bacteria. The D-BPE consists of a cathode, and two anodes filled with [Ru(bpy)3]2+-TPrA and luminol-H2O2 solutions, respectively. By introducing ferrocene-labeled aptamer (Fc-aptamer) on the anodes, the ECL emission signal of [Ru(bpy)3]2+ is reduced, while luminol emits a strong ECL signal.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Applied
Hanyue Xue, Min Cao, Shihui Wang, Yanjin Fei, Xiong Xiong, Ying Yang
Summary: The study established a visual and rapid method for escolar detection using LAMP and MB probe, which can detect low levels of adulteration within 25 minutes. Additionally, it was found that escolar is commonly referred to as white tuna in the Chinese market.
Article
Food Science & Technology
Qiuping Li, Hanyue Xue, Yanjin Fei, Min Cao, Xiaohui Xiong, Xiong Xiong, Ying Yang, Libin Wang
Summary: This study achieved specific detection in LAMP using fluorescently labeled probes, with the DNA produced being precipitated and appearing as different colors for different target species. The optimized duplex LAMP system can visually detect at least 1 ng of DNA.
FOOD CHEMISTRY: MOLECULAR SCIENCES
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)