Article
Chemistry, Analytical
Begum Sen-Dogan, Mehmet Alper Demir, Buket Sahin, Ender Yildirim, Gizem Karayalcin, Sebnem Sahin, Ege Mutlu, Taylan Berkin Toral, Ebru Ozgur, Ozge Zorlu, Haluk Kulah
Summary: This study proposes a microfluidic channel design for efficient enrichment of CTCs from blood, independent of epitopes. Compared to existing designs, the design with hydrofoil-shaped pillars demonstrates higher recovery rates and slightly lower white blood cell depletion rate. The results show that the recovery rate is influenced by the size and deformability variation of the different cell lines. The analysis confirms that the microfluidic chip process does not affect cell viability.
Article
Chemistry, Analytical
Chanyong Park, Abdurhaman Teyib Abafogi, Dinesh Veeran Ponnuvelu, Ilchan Song, Kisung Ko, Sungsu Park
Summary: This study focuses on improving the ATP luminescence assay for the detection of CTCs by using a 3D printed immunomagnetic concentrator (3DPIC) to separate and concentrate CTCs in the blood. The results show that 3DPIC can concentrate cancer cells in blood by 100 times within minutes, enabling the ATP luminescence assay to detect as low as 10 cells in blood, which is approximately 10 times more sensitive than using commercial kits for CTC concentration.
Article
Engineering, Chemical
Xiangzhi Zhang, Xiawei Xu, Yong Ren, Yuying Yan, Aiguo Wu
Summary: An Y-Y shaped microfluidic device was designed to separate NSCLC cells using a dielectrophoresis approach, with a separation efficiency of around 99% achieved under optimal operating conditions. This study presents a potentially efficient, facile, and low-cost route for circulating tumor cell separation, which was optimized through numerical simulations.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Oncology
Songhua Cai, Youjun Deng, Zhe Wang, Junyu Zhu, Chujian Huang, Longde Du, Chunguang Wang, Xiangyang Yu, Wenyi Liu, Chenglin Yang, Lixu Wang, Kai Ma, Rui Huang, Xiaoyu Zhou, Heng Zou, Wenchong Zhang, Yan Huang, Zhi Li, Tiaoping Qin, Tao Xu, Xiaotong Guo, Zhentao Yu
Summary: A novel microfluidics-based CTC separation and enrichment platform was developed, which provided detailed information about CTC. This platform showed exceptional functionality, achieving high rates of CTC recovery and purification, as well as accurate detection, providing intact and viable CTCs for downstream analysis. It also allows for direct analysis of CTC subtypes, protein expression levels, and gene mutations.
FRONTIERS IN ONCOLOGY
(2023)
Review
Chemistry, Analytical
Fulai Li, Hengyi Xu, Yufen Zhao
Summary: As a new type of liquid biopsy, circulating tumor cell (CTC) detection and analysis offer the possibility of real-time monitoring of metastatic development, cancer recurrence, and therapeutic efficacy. The rarity and heterogeneity of CTCs present great challenges, and magnetic particle-based methods show promise for effective CTC capture. Progress has been made in utilizing magnetic particles to enhance CTC capture, which is crucial for cancer diagnosis and prognosis.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Jian Zhou, Alexandra Vorobyeva, Qiyue Luan, Ian Papautsky
Summary: Single-cell analysis has greatly advanced cancer biology by providing abundant information on the molecular landscape of tumor cells responding to external stimuli. This study adapts this concept to analyze the inertial migration of cells and clusters, which is promising for cancer liquid biopsy. High-speed camera tracking reveals the spatial heterogeneity of inertial migration depending on the initial cross-sectional location.
Article
Nanoscience & Nanotechnology
Seung-Ryeol Lee, Youngtaek Kim, Suryong Kim, Jiho Kim, Seonghyuk Park, Stephen Rhee, Dohyun Park, Byungjun Lee, Kyusuk Baek, Ho-Young Kim, Noo Li Jeon
Summary: This study presents a novel injection-molded plastic array 3D universal culture platform (U-IMPACT) that offers a versatile solution for various biological applications. The platform allows for cocultures of different cell types, as well as the cultivation of spheroids and tissues. By utilizing capillary action, the platform enables stable multichannel patterning without the need for modification. Experimental results demonstrate its potential in creating 3D tumor microenvironments and culturing neurospheres.
MICROSYSTEMS & NANOENGINEERING
(2022)
Review
Oncology
Mahmoud Labib, Shana O. Kelley
Summary: Analysis of circulating tumor cells provides valuable insights in precision oncology, revealing associations between CTCs molecular profiles and tumor response to therapy. However, current limitations hinder the widespread clinical implementation of CTCs, suggesting the need for further research and advanced technologies.
MOLECULAR ONCOLOGY
(2021)
Article
Chemistry, Analytical
Kai Zhao, Penglu Zhao, Jianhong Dong, Yunman Wei, Bin Chen, Yanjuan Wang, Xinxiang Pan, Junsheng Wang
Summary: This study demonstrates the successful isolation of circulating tumor cells (CTCs) from blood cells using a combination of dielectrophoresis and magnetophoresis in a microfluidic chip. The results show the potential application of this method in diagnostics.
Article
Biology
Jose Montoya Mira, Ajay A. Sapre, Brett S. Walker, Jesus Bueno Alvarez, Kyle T. Gustafson, Eugene Tu, Jared M. Fischer, Melissa H. Wong, Sadik Esener, Yu-Jui Chiu
Summary: Researchers have developed a label-free dielectrophoretic microfluidic platform for the enrichment of circulating hybrid cells (CHCs), showing promising potential for isolating tumor cells non-invasively from patient blood samples within one hour. They have optimized the device using in vitro models and successfully applied it to clinically relevant mutation analyses in 75% of the samples tested.
COMMUNICATIONS BIOLOGY
(2021)
Review
Chemistry, Analytical
Lujun Wang, Martin Pumera
Summary: 3D printing has been widely used in microfluidic devices, separation sciences, and sample extraction, with great potential for on-demand fabrication of separation tools with the development of new materials.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Jiri Smejkal, Petr Maly, Milan Kuchar, Natalya Panova, Alena Semeradtova, Petr Aubrecht, Marcel Stofik, Jan Maly
Summary: Cell immunocapture microfluidic devices can efficiently capture cells by utilizing small recombinant protein binders (PBs) that bind to cell surface receptors, showing potential applications in medical diagnostics. The study demonstrates the effectiveness of PBs in capturing cells with high affinity and selectivity, providing a flexible and cost-effective method for rare cell immunocapture.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Polymer Science
Sandra Garcia-Rey, Jacob B. Nielsen, Gregory P. Nordin, Adam T. Woolley, Lourdes Basabe-Desmonts, Fernando Benito-Lopez
Summary: Additive manufacturing technology is an emerging method for rapid prototyping that allows for the creation of complex geometries through layer-by-layer fabrication. This research utilized a custom-made resin formulation and high-resolution 3D printing to optimize a prototype for an operational plasma separation modular device.
Article
Oncology
Jing-Jing Yu, Chang Shu, Hui-Yuan Yang, Zhao Huang, Ya-Ni Li, Ran Tao, Yue-Yue Chen, Qian Chen, Xiao-Ping Chen, Wei Xiao
Summary: This study found that CTC clusters are common in hepatocellular carcinoma patients and are associated with an aggressive phenotype. CTC clusters can be used as a biomarker to predict the prognosis of HCC patients at each stage of malignancy, providing evidence for formulating more precise treatment strategies.
FRONTIERS IN ONCOLOGY
(2021)
Article
Chemistry, Analytical
Roya Mohammadali, Morteza Bayareh
Summary: This paper introduces a method of isolating deformable CTCs using inertial-based spiral microchannels and discusses the effects of cell deformability, cell size, number of loops, and channel depth on the hydrodynamic behavior of CTCs. The results demonstrate that this method can be used for sorting and isolating label-free deformable cells at large scales in clinical systems.
Article
Chemistry, Organic
Jia-Bao Liu, Haidar Ali, Muhammad Kashif Shafiq, Ghulam Dustigeer, Parvez Ali
Summary: The research focuses on the applications of topological indices in analyzing the bio-compatibility of chemical compounds in the context of QSAR and QSPR correlations. By combining Chemistry and Graph theory, Chemical graph theory deals with topology and plays a significant role in the development of topological indices. The article specifically explores the use of degree based topological indices in Octahedron networks.
POLYCYCLIC AROMATIC COMPOUNDS
(2023)
Article
Substance Abuse
Neal Shah, Matthew Nali, Cortni Bardier, Jiawei Li, James Maroulis, Raphael Cuomo, Tim K. Mackey
Summary: This study used unsupervised machine learning to analyze the sales of electronic nicotine delivery systems (ENDS) on Instagram. The results showed that there is a significant amount of unregulated ENDS sales on Instagram, including flavored products, and many websites lack age verification. These findings may violate Instagram's policies and US laws, highlighting the need for stronger regulation to prevent youth access to and use of ENDS.
Article
Computer Science, Artificial Intelligence
Lingbo Liu, Zewei Yang, Guanbin Li, Kuo Wang, Tianshui Chen, Liang Lin
Summary: This paper discusses an important task in land remote-sensing analysis, which is the automatic extraction of traffic roads from remote-sensing data. To address this problem, the authors introduce a novel neural network framework that utilizes the complementary information from different data sources to enhance the accuracy and robustness of road extraction.
IEEE TRANSACTIONS ON NEURAL NETWORKS AND LEARNING SYSTEMS
(2023)
Article
Biochemical Research Methods
Yan Yan, Jiaxing Liu, Min Zhang, Yinjie Zhang, Biyun Shi, Xuemei Qin, Chenhui Du
Summary: In this study, quality markers for Ziziphi Spinosae semen (ZSS) were proposed using a combination of metabolic in vivo study and network pharmacology. An UHPLC-Q-Orbitrap-MS method was used to identify and assign components in ZSS, and metabolic networks of flavonoids, saponins, and alkaloids were established. Twelve key bioactive components against insomnia were selected as quality markers for ZSS.
BIOMEDICAL CHROMATOGRAPHY
(2023)
Article
Cell Biology
Nan Shan Zhong, Wei Lai Tong, Yu Zhang, Shi Ning Xiao, Jia Ming Liu, An An Li, Ge Liang Yao, Qing Lin, Zhi Li Liu
Summary: HELQ plays a tumor-suppressive role in non-small-cell lung cancer and has the potential to be a predictive biomarker for prognosis and treatment of lung cancer.
CELL BIOLOGY INTERNATIONAL
(2023)
Article
Materials Science, Paper & Wood
Jianjun Gu, Xiaofei Yan, Dongming Qi, Ruyi Xie, Xiaoming Yang, Yaobang Li, Jiawei Li
Summary: In this study, a durable multifunctional coating was successfully fabricated on cotton fabric, providing it with flame retardant, antibacterial, superhydrophobic and self-cleaning properties. The coated fabric exhibited excellent durability even after multiple washing cycles.
Article
Gastroenterology & Hepatology
Jingxian Hu, Miao Jiang, Hongyan Liu, Hao Zhou, Yajie Wang
Summary: The study finds that endoscopic purse-string sutures appear to be safe and effective in the treatment of high-risk peptic ulcer hemorrhage patients.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Materials Science, Textiles
Shifeng Wu, Jiawei Li, Chongwen Yu
Summary: This paper proposes a simulation method for the fiber arrangement in slub yarn and uses the finite element method to simulate the twist distribution of slub yarn, which is consistent with actual spinning results. The research is significant for further exploration of the properties of slub yarn.
TEXTILE RESEARCH JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Jianming Yang, Xin Yan, Xinru Xu, Yujian Chen, Wei Han, Xianzhi Chai, Xiang Liu, Jiaxing Liu, Chen Liu, Hexin Zhang, Xiao Li, Zhen Zhang, Tie Wang
Summary: Polymeric electromagnetic interference (EMI) shielding materials based on CO2 foaming technology have gained widespread attention due to their efficient use of CO2, high strength, corrosion resistance, and low cost. New design concepts and preparation techniques have led to the development of high-performance EMI shielding materials. This review summarizes the progress made in fabricating EMI shielding composite foams using supercritical carbon dioxide (scCO(2)) foaming and explores the relationship between component/distribution and EMI shielding properties. Additionally, it discusses the application prospects and development challenges of new EMI shielding composite foams.
CHEMISTRY-AN ASIAN JOURNAL
(2023)
Article
Computer Science, Interdisciplinary Applications
Jiawei Li, Pavel Tomin, Hamdi Tchelepi
Summary: There is an increasing interest in developing robust and efficient sequential methods for reservoir simulation. The sequential fully implicit Newton (SFIN) method addresses the slow sequential coupling convergence issue when flow and transport problems are strongly coupled. However, the original SFIN algorithm requires fixed primary variables during the simulation. In this work, strategies are proposed to handle inconsistent primary variables and extend the SFIN method to the natural black-oil formulation.
COMPUTATIONAL GEOSCIENCES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Taotao Zhang, Kuan Yang, Yujiang Chen, Yuran Jiang, Zhifei Zhou, Jiajia Liu, Yang Du, Lulu Wang, Xinxin Han, Xingan Wu, Xiaojing Wang
Summary: This study found that nicotine treatment impairs autophagy function in periodontal ligament stem cells, leading to the production of inflammatory factors. Activation of α7nAChR by nicotine upregulates NEAT1, which in turn decreases autophagy flux by downregulating STX17.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Haoran Liu, Dong Liu, Junchuan Yang, Hanfei Gao, Yuchen Wu
Summary: Organic flexible electronic devices with outstanding properties, such as solution processability, lightweight, and flexibility, have the potential to revolutionize lifestyles. The precise patterning and ordered assembly of organic semiconductors for integration in flexible electronics have attracted attention and rapidly developed. This review focuses on recent advances in the design, patterned assembly, and multifunctional applications of flexible organic field-effect transistors (FOFETs). It introduces typical organic semiconductor materials and material design methods, discusses patterned assembly strategies on flexible substrates, and highlights advanced applications of flexible electronic devices based on organic semiconductor patterns. Future challenges and possible directions for the development of the next generation of flexible electronics are also proposed.
Article
Spectroscopy
Haipei Zou, Huanling Liu, Qingfang Mu, Kai Zhang, Yuzhi Song, Lili Lin, Yuanyuan Xu, Chuan-Kui Wang, Jianzhong Fan
Summary: This study investigates the relationship between molecular structures and luminescent properties, and proposes theoretically efficient TSCT-based TADF molecules. These molecules have a large number of substitutions and adopt twist structures to achieve small energy gaps between the lowest excited states.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Endocrinology & Metabolism
Zixuan Liu, Jing Dai, Xiaodie He, Jiaxi Li, Haixia Zhang, Cheng Ji
Summary: This study aimed to investigate the incidence and influencing factors of postoperative hypoglycemia in diabetic patients during the perioperative period and construct a risk prediction model. Patients with type 2 diabetes admitted to Nanjing Drum Tower Hospital from December 2019 to January 2022 were included. A total of 440 patients were included, and the incidence of postoperative hypoglycemia was 24.78%. Preoperative C-peptide and operation duration were identified as risk factors, while BMI and preoperative fasting blood glucose were protective factors.
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY
(2023)
Article
Computer Science, Artificial Intelligence
Xiang Shi, Yinpeng Liu, Jiawei Liu, Qikai Cheng, Wei Lu
Summary: Scientific papers are crucial for academic communication, but many of them lack in-depth research and present core content ambiguously, hindering the progression of science and technology. To address this challenge, the INTEGrity vERification (INTEGER) task is introduced to help researchers assess the integrity of their papers and verify the clarity of each knowledge unit. A multi-task learning model utilizing Tucker decomposition and span-level attention mechanism is proposed to accurately identify terms and their integrity. Experimental results show the effectiveness of the model.
EXPERT SYSTEMS WITH APPLICATIONS
(2024)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)