Article
Cell Biology
Amit Laxmikant Deshmukh, Marie-Christine Caron, Mohiuddin Mohiuddin, Stella Lanni, Gagan B. Panigrahi, Mahreen Khan, Worrawat Engchuan, Natalie Shum, Aisha Faruqui, Peixiang Wang, Ryan K. C. Yuen, Masayuki Nakamori, Kazuhiko Nakatani, Jean-Yves Masson, Christopher E. Pearson
Summary: Ongoing inchworm-like CAG and CGG repeat expansions in brains may drive neurological disorders like Huntington's disease, fragile X syndrome, and autism. The FAN1 nuclease plays a key role in modifying hyperexpansion rates through binding, dimerizing, and cleaving slipped DNAs. Rare FAN1 variants are associated with individuals with autism and CGG/CCG expansions. Slip-outs of CGG/CCG repeats show exo-nuclease pauses.
Article
Chemistry, Analytical
Na Wu, Yi-Ting Wang, Xiao-Yan Wang, Xu-Wei Chen, Ting Yang, Jian-Hua Wang
Summary: A simple, sensitive DNA sensor was developed utilizing target recycling amplification and 3D DNA walker cascade amplification for nucleic acid detection. The biosensor demonstrated a low detection limit and wide analytical range, and its practical application potential was confirmed through spiking experiments in human serum and urine samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Jianwen Wan, Yiyi Liang, Qiong Hu, Zhiwen Liang, Wenxing Feng, Yiyan Tian, Shiqi Li, Zhuojun Ye, Mingru Hong, Dongxue Han, Li Niu
Summary: The study presents an amplification-free ratiometric electrochemical aptasensor for the rapid quantification of therapeutic monoclonal antibodies. The aptasensor exhibits high selectivity and satisfactory reproducibility and robustness, making it a promising tool for point-of-care detection of therapeutic mAbs.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Xinyue Yuwen, Yunying Feng, Wan Huang, Xin Li, Guosong Lai
Summary: In this study, a novel ratiometric fluorescence biosensing method was developed for the convenient determination of bleomycin (BLM) using two target-sensitive fluorescent probes. This method showed excellent analytical performance, convenient manipulation, and low assay cost, indicating its high potential for future applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Acoustics
Shenchao Shi, Ruizheng Zhong, Lele Li, Chidan Wan, Can Wu
Summary: In this study, MXene nanoflakes coupled with graphene nanosheets (graphene@MXene) were prepared for the first time using a simple ultrasound-assisted liquid-phase exfoliation method in N-methylpyrrolidone (NMP) solvent. The effect of different types of solvent, sonication temperature, and sonication duration time on the properties of graphene@MXene hybrids were systematically investigated.
ULTRASONICS SONOCHEMISTRY
(2022)
Article
Food Science & Technology
Chengyuan Wu, Xinjie Wang, Ling Guo, Xingxu Huang, Lina Wu, He Huang
Summary: A neoteric electrochemical biosensor based on an exonuclease III (Exo III)-assisted recycling reaction triggering the trans-cleavage ability of CRISPR-Cas12a was developed for the selective and ultrasensitive detection of ochratoxin A (OTA). The method showed good selectivity and sensitivity for OTA determination with a detection limit of 0.74 fg/mL. Furthermore, the established method could sensitively identify OTA in spiked rice and peanut samples, demonstrating its application potential for practical detection.
Article
Chemistry, Analytical
Li Hou, Xuanhan Zhang, Yuxiu Huang, Min Wang, Xiaoyu Chen, Tianran Lin, Yanhui Tan, Shulin Zhao
Summary: A sensitive and ratiometric electrochemical biosensor was developed for the determination of dimethoate via alkaline phosphatase (ALP) mediated dissolution of nano-MnO2 and [Ru(NH3)(6)](3+)(Ru(III)) redox recycling. The biosensor showed good performance in detecting dimethoate with high sensitivity and a detection limit of 6.3 pg mL(-1).
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Biophysics
Yanli Ji, Jiaxin Guo, Baoxian Ye, Guanghua Peng, Chi Zhang, Lina Zou
Summary: A high-sensitivity cancer biosensor was developed using DNA nanotechnology, which achieved detection of ultra-low levels of carcinoembryonic antigen through signal amplification.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Ping Wang, Huikai Ma, Yanfeng Zhu, Wei Feng, Mengyao Su, Sanqiang Li, Hongju Mao
Summary: In this work, a novel ratiometric electrochemical aptasensor based on dual-amplification mechanism was designed. The aptasensor showed high specificity, stability, and reproducibility. Furthermore, it can be applied for the detection of other targets.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Chenyi Zeng, Xin Liu, Bin Wang, Rui Qin, Qiang Zhang
Summary: The construction of logic circuits is crucial to DNA computing. A double-stranded separation (DSS) strategy combining toehold-mediated strand displacement with exonuclease III (Exo III) is proposed. This strategy allows for effective scalability of molecular logic circuits and enables multiple logic computing capabilities.
Article
Chemistry, Analytical
Yuancong Xu, Nan Cheng, Yunbo Luo, Kunlun Huang, Qiaoying Chang, Guofang Pang, Wentao Xu
Summary: This study presents a self-fluorescence aptasensor for pesticide detection based on Exo III-assisted catalytic hairpin assembly. The sensor has high sensitivity and low background noise. By modifying the spatial configuration, the aptamer can specifically recognize the target and drive the cyclic amplification process, increasing the detection efficiency.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Biochemical Research Methods
Huikai Ma, Ping Wang, Yaoyao Xie, Jinghan Liu, Wei Feng, Sanqiang Li
Summary: A novel ratiometric electrochemical aptasensor was developed for the detection of CEA, showing great potential in diluted serum detection. The aptasensor utilized a hairpin DNA probe and exonuclease I-assisted target recycling amplification strategy to achieve the detection of CEA through the change in ratiometric electrochemical signal.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Materials Science, Biomaterials
Zhi Li, Jingwen Zhang, Ge Dai, Feifei Luo, Zhaohui Chu, Xing Geng, Pingang He, Fan Zhang, Qingjiang Wang
Summary: Cu2O-rGO nanozyme was prepared and used for GA detection, monitoring GA levels by the ratio method to improve accuracy.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Nanoscience & Nanotechnology
Thiba Nagaraja, Rajavel Krishnamoorthy, Kh M. Asif Raihan, Brice Lacroix, Suprem R. Das
Summary: Understanding the electrochemical transport of ions at the interface of nanoscale materials and its environment is crucial for building electrochemical sensors. This study successfully manufactured high-quality graphene nanoink and used it to fabricate printed phosphate ion electrochemical sensors, overcoming limitations in monitoring phosphate ions.
ACS APPLIED NANO MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Ramin Boroujerdi, Richard Paul
Summary: Sensors developed from nanomaterials, especially graphene, have gained significant attention in the past two decades due to their exceptional properties and potential applications in various fields, including drug detection.
Article
Engineering, Environmental
Miao Dai, Jingbo Zhang, Na Liu, Xiu-Hua Zhang
Summary: The researchers developed Lignin-loaded dextran/glycol nanoparticles and investigated their application in wound healing; the experimental results demonstrated that this nanomaterial can promote wound healing and possess antibacterial activity, making it a potential novel dressing material.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Nanoscience & Nanotechnology
Hang Zhong, Wenbo Li, Yin Huang, Duoling Cao, Congqiang Zhang, Huaxi Bao, Zhiguang Guo, Li Wan, Xu Zhang, Xiuhua Zhang, Yuebin Li, Xiaoming Ren, Xianbao Wang, Dominik Eder, Kai Wang, Shengzhong Frank Liu, Shimin Wang
Summary: In this work, tetrabutylammonium acetate (TBAAc) was introduced as a buffer layer to improve the power conversion efficiency and stability of CsPbI3 perovskite solar cells. The optimized device achieved a high PCE of 12.79% and exhibited excellent stability, retaining over 83% of its initial PCE after 350 hours.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Chengyi Xiong, Jing Huang, Heng Liu, Miao-Miao Chen, Wei Wen, Xiuhua Zhang, Shengfu Wang
Summary: Metal organic frameworks (MOFs) based sensors have shown numerous advantages in sensitive detection and can enhance the sensitivity of the sensing system. This article introduces a novel electrochemiluminescence (ECL) sensor that utilizes encapsulated multifunctional metal organic frameworks (Ru-MOFs) as nanocarriers and nanoreactors for the sensitive detection of H2S.
Article
Crystallography
Xiu-Hua Zhang, Jin-Xiao Mi, Zhi-Biao Hu, Ze-Hai Qiu, Wu-Hua Chen
Summary: The compound is monoclinic with the cell parameters of a=17.5779(6) Å, b=9.0747(3) Å, c=9.4946(3) Å, and β=96.636(3)°. The unit cell contains one molecule and the volume is 1504.38(9) ų. The R(gt)(F) value is 0.0273 and the wR(ref)(F(2)) value is 0.0646, with a temperature of 293(2) K.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2022)
Article
Engineering, Environmental
Tongyao Wang, Tong Chen, Junlun Zhu, Suxiao Wang, Wei Wen, Xiuhua Zhang, Huadong Tang, Jichao Liang, Shengfu Wang, Huayu Xiong, Huayu Xiong
Summary: This study developed a novel nanoreactor that utilizes glucose oxidation to generate highly active radicals for starvation therapy and chemodynamic therapy. It also incorporates photothermal enhancement and release of copper ions for enhanced angiogenesis, thereby combating persistent inflammation and bacterial infection during wound healing.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Analytical
Xi Zhang, Junlun Zhu, Zhen Wu, Wei Wen, Xiuhua Zhang, Shengfu Wang
Summary: An electrochemical sensor based on gold nano-particles and COFs was developed for the detection of BPA, showing high sensitivity and satisfactory recovery in real water samples.
ANALYTICA CHIMICA ACTA
(2023)
Review
Chemistry, Multidisciplinary
Yao Xiao, Chengyi Xiong, Miao-Miao Chen, Shengfu Wang, Lei Fu, Xiuhua Zhang
Summary: With the development of two-dimensional materials, transition metal dichalcogenides (TMDs) have become popular model materials for both fundamental sciences and practical applications. This review provides a comprehensive overview of the structure modulation of TMDs, including various modulated structures and their characteristics. It also summarizes the recent progress in modulating methods, mechanisms, properties, and applications of modulated TMD structures, as well as the challenges and prospects in this field.
CHEMICAL SOCIETY REVIEWS
(2023)
Article
Chemistry, Physical
Wenbo Li, Duoling Cao, Xiaorui Zhu, Zhiguang Guo, Li Wan, Xu Zhang, Xiuhua Zhang, Yuebin Li, Xiaoming Ren, Xianbao Wang, Dominik Eder, Shimin Wang
Summary: This study demonstrates a facile approach of optimizing the SnO2-ETL and CsPbI3 film to construct efficient carbon CE-based CsPbI3 solar cells, resulting in a relatively high power conversion efficiency of 12.85%.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Xiaoxue Xi, Zhen Wu, Xiuhua Zhang, Yuebin Li, Yuandi Zhao, Wei Wen, Shengfu Wang
Summary: The development of a tumorspecific nanosensor with an endogenous protease-activatable manner remains a challenge in the in situ detection of low-content cancer biomarkers. This study proposes an endogenous protease-activatable nanosensor that combines electrochemical detection with optical imaging to achieve AND-gated and dual-model sensing of miRNA-21 in living tumor cells. The nanosensor can only be activated by dual keys simultaneously, improving the tumor-to-healthy cells ratio and providing new opportunities for the diagnosis and treatment of cancer at the single-cell level.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Lebao Mao, Yao Xiao, Hao Liu, Xiuhua Zhang, Shengfu Wang, Wei-Hua Huang, Miao-Miao Chen
Summary: Hydrolysis-resistant CsPbBr3/reduced graphene oxide nanoscrolls (CsPbBr3/rGO NSs) with excellent optical properties and stability were obtained through a solvent-assisted self-rolling process. The CsPbBr3 QDs embedded in rGO nanosheets prevent water infiltration and maintain superb optical properties. The CsPbBr3/rGO NSs exhibit enhanced anode photocurrent response and demonstrate high sensitivity and anti-interference ability in molecular imprinted PEC sensors for mycotoxin detection.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Applied
Qian Wang, Chengyi Xiong, Jingwen Li, Qianchun Deng, Xiuhua Zhang, Shengfu Wang, Miao-Miao Chen
Summary: In this study, methylamine perovskite quantum dots (MP QDs) encapsulated by ZIF-8 metal-organic frameworks (MP QDs@ZIF-8) were prepared for the detection of aflatoxin B1 (AFB1). The constructed electrochemiluminescence (ECL) sensor showed good selectivity and ultra-sensitivity, with a wide linear range for AFB1 quantification. The satisfactory recoveries in corn samples demonstrated the reliable practicability of the proposed sensor for AFB1 assay. This work provided a novel pathway for designing high-performance ECL sensing platforms in food safety.
Article
Engineering, Mechanical
Huan Yan, Peitang Wei, Lihong Su, Huaiju Liu, Dong Wei, Xiuhua Zhang, Guanyu Deng
Summary: In this study, the rolling-sliding contact fatigue (RSCF) failures of AISI 9310 gear steel were thoroughly analyzed. The fatigue life, microstructure and crystallographic orientation evolution, and microhardness and residual stress distributions were characterized. The RSCF life of AISI 9310 steel roller decreased with increasing maximum contact pressure, but could be improved by shot peening due to enhanced microhardness and compressive residual stress. Main fatigue damage near the roller surface included inclined cracks, micro-pitting, spallation, and plastic deformation. The RSCF process also resulted in preferred crystallographic orientations.
INTERNATIONAL JOURNAL OF FATIGUE
(2023)
Article
Engineering, Multidisciplinary
Xiuhua Zhang, He Ke, Mingxin Chi, Ruochen Wang
Summary: In this study, the impact of paper straw board (PSB) on the seismic performance of cold-formed thin-walled steel composite walls (CFSCWs) was investigated, and the experimental results of CFSCW with PSB cladding were compared with those of CFSCW with other wall panel cladding. The findings suggest that PSB can effectively enhance the shear bearing capacity of the composite wall, and its lightweight nature makes CFSCW with PSB cladding easy to construct. Finite element analysis was conducted using ANSYS software to simulate CFSCW with one-sided PSB cladding and analyze the relevant parameters affecting seismic performance. The results indicate that reducing stud spacing, peripheral self-tapping screw spacing, increasing wall panel and steel skeleton edge stud section thickness can effectively improve shear bearing capacity and lateral stiffness within a certain range. Additionally, decreasing the wall height-to-width ratio improves lateral stiffness but decreases unit width shear bearing capacity.
JOURNAL OF THE CHINESE INSTITUTE OF ENGINEERS
(2023)
Article
Nanoscience & Nanotechnology
Weijian Wang, Gang Yu, Lebao Mao, Sanam Attique, Zhiwei Si, Qing Yang, Yongqiang Zhang, Guiqiu Huang, Haiyan Zhang, Ximing Yan, Shengfu Wang, Xiuhua Zhang
Summary: Researchers have designed perovskite solar cells with mesoporous antireflection coatings, which significantly improve the photocurrent density of the cells. The study offers a fresh approach to the development of highly efficient perovskite and perovskite/silicon tandem solar cells.
ADVANCED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jinrong Liu, Yongzhong Jiang, Wei Wen, Xiuhua Zhang, Zhen Wu, Shengfu Wang
Summary: A novel and universal single-particle collision electrochemistry (SPCE) biosensor based on the collision and oxidation of single silver nanoparticles (Ag NPs) was proposed for sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The biosensor showed enhanced detection sensitivity and practicability of SPCE in biosensing by increasing the collision frequency of Ag NPs on polysulfide-functionalized gold ultra-microelectrodes (Ps-Au UMEs). Additionally, the biosensor achieved successful detection of SARS-CoV-2 in nasopharyngeal swab samples, demonstrating its potential for clinically relevant diagnosis.
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
