Astroglial contribution to tau-dependent neurodegeneration

Altered brain arginine metabolism in a mouse model of tauopathy

(2019) Pranav Vemula et al.   AMINO ACIDS

Extracellular Monomeric Tau Is Internalized by Astrocytes

(2019) Juan Ramón Perea et al.   Frontiers in Neuroscience

Cellular and regional vulnerability in frontotemporal tauopathies

(2019) Shelley L. Forrest et al.   ACTA NEUROPATHOLOGICA

Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tauversusα-synuclein and β-amyloid aggregates

(2018) Barbara E. Stopschinski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tau clearance improves astrocytic function and brain glutamate-glutamine cycle

(2018) Michaeline L. Hebron et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Activated forms of astrocytes with higher GLT-1 expression are associated with cognitive normal subjects with Alzheimer pathology in human brain

(2018) Eiji Kobayashi et al.   Scientific Reports

TFEB enhances astroglial uptake of extracellular tau species and reduces tau spreading

(2018) Heidi Martini-Stoica et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline

(2018) Tyler J. Bussian et al.   NATURE

Reactivity of microglia and astrocytes after an excitotoxic injury induced by kainic acid in the rat spinal cord

(2018) Carolina Natalia Zanuzzi et al.   TISSUE & CELL

Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons

(2017) Roberto Piacentini et al.   GLIA

Glial contributions to neurodegeneration in tauopathies

(2017) Cheryl E. G. Leyns et al.   Molecular Neurodegeneration

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Inflammatory pathology markers (activated microglia and reactive astrocytes) in early and late onset Alzheimer disease: a post mortem study

(2017) R. Taipa et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Astrocytes in mouse models of tauopathies acquire early deficits and lose neurosupportive functions

(2017) Marta Sidoryk-Wegrzynowicz et al.   Acta Neuropathologica Communications

Tau and tauopathies

(2016) Thomas Arendt et al.   BRAIN RESEARCH BULLETIN

Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion

(2016) A. Verkhratsky et al.   EMBO JOURNAL

Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer’s Disease

(2016) Yasmina Manso et al.   JOURNAL OF ALZHEIMERS DISEASE

Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model

(2016) Cristian A. Lasagna-Reeves et al.   NEURON

The Rise and Fall of the d -Serine-Mediated Gliotransmission Hypothesis

(2016) Herman Wolosker et al.   TRENDS IN NEUROSCIENCES

Propagation of tau pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies

(2015) Jada Lewis et al.   ACTA NEUROPATHOLOGICA

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

Astrocyte Regulation of Synaptic Behavior

(2014) Nicola J. Allen   Annual Review of Cell and Developmental Biology

Glia in the pathogenesis of neurodegenerative diseases

(2014) Alexei Verkhratsky et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Glutamate and GABA-Metabolizing Enzymes in Post-mortem Cerebellum in Alzheimer’s Disease: Phosphate-Activated Glutaminase and Glutamic Acid Decarboxylase

(2014) G. Sh. Burbaeva et al.   CEREBELLUM

Hypermetabolic State in the 7-Month-Old Triple Transgenic Mouse Model of Alzheimer'S Disease and the Effect of Lipoic Acid: A 13C-NMR Study

(2014) Harsh Sancheti et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuronal and Astrocytic Metabolism in a Transgenic Rat Model of Alzheimer's Disease

(2014) Linn Hege Nilsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Astrocytic inclusions in progressive supranuclear palsy and corticobasal degeneration

(2014) Mari Yoshida   NEUROPATHOLOGY

Astrocyte response to motor neuron injury promotes structural synaptic plasticity via STAT3-regulated TSP-1 expression

(2014) Giulia E. Tyzack et al.   Nature Communications

Tau pathology and neurodegeneration

(2013) Maria Grazia Spillantini et al.   LANCET NEUROLOGY

The SLC38 family of sodium–amino acid co-transporters

(2013) Stefan Bröer   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Age-related changes in neuroactive steroid levels in 3xTg-AD mice

(2012) Donatella Caruso et al.   NEUROBIOLOGY OF AGING

Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease

(2011) Tommaso Cassano et al.   NEUROBIOLOGY OF AGING

Roles of glutamine in neurotransmission

(2011) Jan Albrecht et al.   Neuron Glia Biology

P301S Mutant Human Tau Transgenic Mice Manifest Early Symptoms of Human Tauopathies with Dementia and Altered Sensorimotor Gating

(2011) Hiroki Takeuchi et al.   PLoS One

Knockout of GAD65 has Major Impact on Synaptic GABA Synthesized from Astrocyte-Derived Glutamine

(2010) Anne B Walls et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cell-Mediated Neuroprotection in a Mouse Model of Human Tauopathy

(2010) D. W. Hampton et al.   JOURNAL OF NEUROSCIENCE

Sonic Hedgehog Regulates Discrete Populations of Astrocytes in the Adult Mouse Forebrain

(2010) A. D. R. Garcia et al.   JOURNAL OF NEUROSCIENCE

Reactive astrocytes give neurons less support: implications for Alzheimer's disease

(2010) Megan L. Steele et al.   NEUROBIOLOGY OF AGING

Early behavioural markers of disease in P301S tau transgenic mice

(2009) Maria Luisa Scattoni et al.   BEHAVIOURAL BRAIN RESEARCH

Tau-directed drug discovery for Alzheimer's disease and related tauopathies: A focus on tau assembly inhibitors

(2009) Kurt R. Brunden et al.   EXPERIMENTAL NEUROLOGY

Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains

(2009) Kumi Sasaki et al.   FEBS LETTERS

Prion-like mechanisms in neurodegenerative diseases

(2009) Bess Frost et al.   NATURE REVIEWS NEUROSCIENCE

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

(2008) L. M. Ittner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA