Establishment of X chromosome inactivation and epigenomic features of the inactive X depend on cellular contexts

Single-Cell RNA-Seq Reveals Lineage and X Chromosome Dynamics in Human Preimplantation Embryos

(2016) Sophie Petropoulos et al.   CELL

Enlightening the contribution of the dark matter to the X chromosome inactivation process in mammals

(2016) Miguel Casanova et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

(2016) Andrew Keniry et al.   Epigenetics & Chromatin

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

Erosion of X Chromosome Inactivation in Human Pluripotent Cells Initiates with XACT Coating and Depends on a Specific Heterochromatin Landscape

(2015) Céline Vallot et al.   Cell Stem Cell

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

(2015) Ronan Chaligné et al.   GENOME RESEARCH

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation

(2015) A. Minajigi et al.   SCIENCE

A rapid passage through a two-active-X-chromosome state accompanies the switch of imprinted X-inactivation patterns in mouse trophoblast stem cells

(2015) Julie Prudhomme et al.   Epigenetics & Chromatin

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

(2015) Benoit Moindrot et al.   Cell Reports

Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells

(2015) Asun Monfort et al.   Cell Reports

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

The Two Active X Chromosomes in Female ESCs Block Exit from the Pluripotent State by Modulating the ESC Signaling Network

(2014) Edda G. Schulz et al.   Cell Stem Cell

Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome

(2014) Simão Teixeira da Rocha et al.   MOLECULAR CELL

Lineage-specific regulation of imprinted X inactivation in extraembryonic endoderm stem cells

(2014) Sarra Merzouk et al.   Epigenetics & Chromatin

A prominent and conserved role for YY1 in Xist transcriptional activation

(2014) Mélanie Makhlouf et al.   Nature Communications

Jpx RNA Activates Xist by Evicting CTCF

(2013) Sha Sun et al.   CELL

Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

(2013) Eda Yildirim et al.   CELL

The mammalian germline as a pluripotency cycle

(2013) H. G. Leitch et al.   DEVELOPMENT

Unusual chromatin status and organization of the inactive X chromosome in murine trophoblast giant cells

(2013) C. Corbel et al.   DEVELOPMENT

Cdyl, a New Partner of the Inactive X Chromosome and Potential Reader of H3K27me3 and H3K9me2

(2013) M. Escamilla-Del-Arenal et al.   MOLECULAR AND CELLULAR BIOLOGY

XACT, a long noncoding transcript coating the active X chromosome in human pluripotent cells

(2013) Céline Vallot et al.   NATURE GENETICS

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

(2013) J. M. Engreitz et al.   SCIENCE

Site-Specific Silencing of Regulatory Elements as a Mechanism of X Inactivation

(2012) J. Mauro Calabrese et al.   CELL

Derivation Conditions Impact X-Inactivation Status in Female Human Induced Pluripotent Stem Cells

(2012) Kiichiro Tomoda et al.   Cell Stem Cell

Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

(2012) Shila Mekhoubad et al.   Cell Stem Cell

Reactivation of the inactive X chromosome in development and reprogramming

(2012) Tatsuya Ohhata et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Satb1 and Satb2 Are Dispensable for X Chromosome Inactivation in Mice

(2012) Robert Nechanitzky et al.   DEVELOPMENTAL CELL

The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome

(2012) Andrea H. Horakova et al.   HUMAN MOLECULAR GENETICS

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

(2012) Cristina Gontan et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells

(2011) Pablo Navarro et al.   HUMAN GENETICS

Evolutionary diversity and developmental regulation of X-chromosome inactivation

(2011) Martin Escamilla-Del-Arenal et al.   HUMAN GENETICS

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

(2011) Ikuhiro Okamoto et al.   NATURE

Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster

(2011) Xinxian Deng et al.   NATURE GENETICS

Linking X chromosome inactivation to pluripotency: Necessity or fate?

(2011) Mélanie Makhlouf et al.   TRENDS IN MOLECULAR MEDICINE

RNF12 Activates Xist and Is Essential for X Chromosome Inactivation

(2011) Tahsin Stefan Barakat et al.   PLoS Genetics

Identification of regulatory elements flanking human XIST reveals species differences

(2010) Samuel C Chang et al.   BMC MOLECULAR BIOLOGY

The Long Noncoding RNA, Jpx, Is a Molecular Switch for X Chromosome Inactivation

(2010) Di Tian et al.   CELL

Female Human iPSCs Retain an Inactive X Chromosome

(2010) Jason Tchieu et al.   Cell Stem Cell

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region

(2010) Corinne Chureau et al.   HUMAN MOLECULAR GENETICS

Molecular coupling of Tsix regulation and pluripotency

(2010) Pablo Navarro et al.   NATURE

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo

(2010) P. J. Rugg-Gunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

(2010) J. Hanna et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNF12 Is an X-Encoded Dose-Dependent Activator of X Chromosome Inactivation

(2009) Iris Jonkers et al.   CELL

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

SATB1 Defines the Developmental Context for Gene Silencing by Xist in Lymphoma and Embryonic Cells

(2009) Ruben Agrelo et al.   DEVELOPMENTAL CELL

ConteXt of change-X inactivation and disease

(2009) Ruben Agrelo et al.   EMBO Molecular Medicine

High-resolution analysis of epigenetic changes associated with X inactivation

(2009) H. Marks et al.   GENOME RESEARCH

Dynamic changes in paternal X-chromosome activity during imprinted X-chromosome inactivation in mice

(2009) C. Patrat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

(2008) Matthias Stadtfeld et al.   Cell Stem Cell

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

(2008) F. M. Pauler et al.   GENOME RESEARCH

X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected

(2008) Lisa L. Hall et al.   JOURNAL OF CELLULAR PHYSIOLOGY

X Chromosome Activity in Mouse XX Primordial Germ Cells

(2008) Susana M. Chuva de Sousa Lopes et al.   PLoS Genetics

A Dual Origin of the Xist Gene from a Protein-Coding Gene and a Set of Transposable Elements

(2008) Eugeny A. Elisaphenko et al.   PLoS One

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Coupling of Xist Regulation and Pluripotency

(2008) P. Navarro et al.   SCIENCE