Engaging Aldehydes in CuH-Catalyzed Reductive Coupling Reactions: Stereoselective Allylation with Unactivated 1,3-Diene Pronucleophiles

CuH-Catalyzed Enantioselective Ketone Allylation with 1,3-Dienes: Scope, Mechanism, and Applications

(2019) Chengxi Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Allylation Using Allene, a Petroleum Cracking Byproduct

(2019) Richard Y. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Asymmetric Reductive Allylation of Ketones with 1,3-Dienes

(2019) Bin Fu et al.   ORGANIC LETTERS

Direct Formic Acid Mediated Z -Selective Reductive Coupling of Dienes and Aldehydes

(2019) Christopher Cooze et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Tandem Hydrocupration and Diastereo- and Enantioselective Borylalkyl Addition to Aldehydes

(2018) Jaesook Yun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereodivergent Catalysis

(2018) Irina P. Beletskaya et al.   CHEMICAL REVIEWS

Intermolecular Metal-Catalyzed Reductive Coupling of Dienes, Allenes, and Enynes with Carbonyl Compounds and Imines

(2018) Michael Holmes et al.   CHEMICAL REVIEWS

2-Azadienes as Reagents for Preparing Chiral Amines: Synthesis of 1,2-Amino Tertiary Alcohols by Cu-Catalyzed Enantioselective Reductive Couplings with Ketones

(2018) Kangnan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Regio- and Enantioselective CuH-Catalyzed Ketone Allylation with Terminal Allenes

(2018) Erica Y. Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of anti-1,2-Diamines by Cu-Catalyzed Reductive Couplings of Azadienes with Aldimines and Ketimines

(2018) Xinxin Shao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu-Catalyzed Enantioselective Reductive Coupling of 1,3-Dienes and Aldimines

(2018) Mingfeng Li et al.   ORGANIC LETTERS

Enantioselective Formation of CF3-Bearing All-Carbon Quaternary Stereocenters via C–H Functionalization of Methanol: Iridium Catalyzed Allene Hydrohydroxymethylation

(2017) Michael Holmes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Regio- and Enantioselective Copper-Catalyzed Reductive Hydroxymethylation of Styrenes and 1,3-Dienes with CO2

(2017) Yong-Yuan Gui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regiodivergent and Diastereoselective CuH-Catalyzed Allylation of Imines with Terminal Allenes

(2016) Richard Y. Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-BINAP Catalyzed Alcohol C–H tert-Prenylation via 1,3-Enyne Transfer Hydrogenation: Beyond Stoichiometric Carbanions in Enantioselective Carbonyl Propargylation

(2016) Khoa D. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed Enantioselective Addition of Styrene-Derived Nucleophiles to Imines Enabled by Ligand-Controlled Chemoselective Hydrocupration

(2016) Yang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Formation of All-Carbon Quaternary Centers via C–H Functionalization of Methanol: Iridium-Catalyzed Diene Hydrohydroxymethylation

(2016) Khoa D. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-catalyzed asymmetric addition of olefin-derived nucleophiles to ketones

(2016) Y. Yang et al.   SCIENCE

Metal-catalyzed reductive coupling of olefin-derived nucleophiles: Reinventing carbonyl addition

(2016) Khoa D. Nguyen et al.   SCIENCE

Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products

(2013) Miguel Yus et al.   CHEMICAL REVIEWS

Ruthenium Catalyzed Hydrohydroxyalkylation of Isoprene with Heteroaromatic Secondary Alcohols: Isolation and Reversible Formation of the Putative Metallacycle Intermediate

(2013) Boyoung Y. Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simple organic molecules as catalysts for enantioselective synthesis of amines and alcohols

(2013) Daniel L. Silverio et al.   NATURE

Asymmetric Methallylation of Ketones Catalyzed by a Highly Active Organocatalyst 3,3′-F2-BINOL

(2013) Yongda Zhang et al.   ORGANIC LETTERS

Regiodivergent reductive coupling of 2-substituted dienes to formaldehyde employing ruthenium or nickel catalyst: hydrohydroxymethylation via transfer hydrogenation

(2013) Alexander Köpfer et al.   Chemical Science

Diastereo- and Enantioselective Iridium-Catalyzed Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level: 1,3-Enynes as Allenylmetal Equivalents

(2012) Laina M. Geary et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Copper-Catalyzed Reductive Coupling of Alkenylazaarenes with Ketones

(2012) Aakarsh Saxena et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective C-H Crotylation of Primary Alcohols via Hydrohydroxyalkylation of Butadiene

(2012) J. R. Zbieg et al.   SCIENCE

Catalytic Enantioselective Allylation of Carbonyl Compounds and Imines

(2011) Miguel Yus et al.   CHEMICAL REVIEWS

Diastereo- and Enantioselective Ruthenium-Catalyzed Hydrohydroxyalkylation of 2-Silyl-butadienes: Carbonylsyn-Crotylation from the Alcohol Oxidation Level

(2011) Jason R. Zbieg et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Hydrohydroxyalkylation of Butadiene: Carbonyl Crotylation

(2010) Jason R. Zbieg et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Carbonyl Reverse Prenylation from the Alcohol or Aldehyde Oxidation Level Employing 1,1-Dimethylallene as the Prenyl Donor

(2009) Soo Bong Han et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

All-Carbon Quaternary Centers via Ruthenium-Catalyzed Hydroxymethylation of 2-Substituted Butadienes Mediated by Formaldehyde: Beyond Hydroformylation

(2009) Tomas Smejkal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-Catalyzed Reductive Coupling Reaction of Aldehydes with Conjugated Dienes Promoted by Triethylborane

(2009) Masanari Kimura et al.   ORGANIC LETTERS

Uniting Anion Relay Chemistry with Pd-Mediated Cross Coupling: Design, Synthesis and Evaluation of Bifunctional Aryl and Vinyl Silane Linchpins

(2009) Amos B. Smith et al.   ORGANIC LETTERS

Carbonyl Propargylation from the Alcohol or Aldehyde Oxidation Level Employing 1,3‐Enynes as Surrogates to Preformed Allenylmetal Reagents: A Ruthenium‐Catalyzed CC Bond‐Forming Transfer Hydrogenation

(2008) Ryan L. Patman et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Synthesis of Tertiary Alcohols and α-Tertiary Amines via Cu-Catalyzed C−C Bond Formation to Ketones and Ketimines

(2008) Masakatsu Shibasaki et al.   CHEMICAL REVIEWS

Ruthenium-Catalyzed C−C Bond Forming Transfer Hydrogenation: Carbonyl Allylation from the Alcohol or Aldehyde Oxidation Level Employing Acyclic 1,3-Dienes as Surrogates to Preformed Allyl Metal Reagents

(2008) Fumitoshi Shibahara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium Catalyzed C−C Bond Formation via Transfer Hydrogenation: Branch-Selective Reductive Coupling of Allenes to Paraformaldehyde and Higher Aldehydes

(2008) Ming-Yu Ngai et al.   ORGANIC LETTERS

Iridium-Catalyzed C−C Coupling via Transfer Hydrogenation:  Carbonyl Addition from the Alcohol or Aldehyde Oxidation Level Employing 1,3-Cyclohexadiene

(2008) John F. Bower et al.   ORGANIC LETTERS