期刊
BIOCONJUGATE CHEMISTRY
卷 27, 期 7, 页码 1584-1587出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.bioconjchem.6b00298
关键词
-
类别
资金
- Beneficentia Stiftung (Vaduz, Liechtenstein)
- AIRC [IG-12085]
The X-ray structure of the adduct formed in the reaction between the gold N-heterocyclic carbene compound Au(NHC)Cl (with NHC = 1-butyl-3-methyl-imidazole-2-ylidene) and the model protein thaumatin is reported here. The structure reveals binding of Au(NHC)(+) fragments to distinct protein sites. Notably, binding of the gold compound occurs at lysine side chains and at the N-terminal tail; the metal binds the protein after releasing Cl- ligand, but retaining NHC fragment.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据