Article
Biochemistry & Molecular Biology
Mao-Ling Sun, Hai-Yun Lai, Na-Yu Chong, Dong-Fan Liu, Zhen-Yi Zhang, Bo Pang, Jun Yao
Summary: A new method for detecting HBV using a combination of MIRA and LFD technologies has been developed, which is simple, rapid, and accurate, making it particularly suitable for resource-limited regions.
FRONTIERS IN MOLECULAR BIOSCIENCES
(2021)
Article
Immunology
Hong Lin, Song Zhao, Yanhong Liu, Lei Shao, Yuying Ye, Nizhen Jiang, Kun Yang
Summary: The newly designed RAA-LFD detection method is suitable for reliably detecting Plasmodium species in low-resource environments with limited laboratory capabilities. The method is performed in an incubator at 37 degrees Celsius for 15 minutes, with visible amplicons on flow dipsticks within 3 minutes. Sensitivity for a single recombinant plasmid was 1 copy per microliter, with sensitivities for genomic DNA from patients infected with P. falciparum, P. vivax, P. ovale, and P. malariae ranging from 0.1pg/ul to 100pg/ul. Overall sensitivity was 100pg/ul.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Wenwen Liu, Gang Lu, Yu Wang, Zhenghong Chen, Yunyun Gao, Zhipeng Yin, Yi Wu, Xiaoqian Lv, Pengbo Guo, Yinghui Zhao
Summary: In order to eradicate Helicobacter pylori (H. pylori) and reduce the risk of gastric cancer, a novel loop-mediated isothermal amplification-lateral flow dipstick (LAMP-LFD) method was established for H. pylori detection.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Veterinary Sciences
Chengyuan Ji, Yiqiu Feng, Ruini Sun, Qibing Gu, Yao Zhang, Jiale Ma, Zihao Pan, Huochun Yao
Summary: In this study, a novel multienzyme isothermal rapid amplification (MIRA) and lateral flow dipstick (LFD) combination assay were developed for rapid on-site detection of Bovine coronavirus (BCoV) infection. The assay was highly specific and sensitive, comparable to a published reverse transcription quantitative PCR (RT-qPCR) assay for BCoV detection. It did not require sophisticated instruments and the results could be observed with eyes.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Shiqian Fu, Xue Qin, Zhenghui Wang, Xinyan Yang, Sihan Chen, Tao Yang, Haonan Jin, Chaoxin Man, Yujun Jiang
Summary: This study utilized whole genome sequence analysis to identify unique DNA fragments of C. sakazakii, designing specific and stable primers for detection using LAMP and PCR techniques. By combining LAMP with LFD, a rapid and highly specific method for detecting C. sakazakii was developed, showing potential for use in detecting the pathogen in powdered infant formula.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Environmental Sciences
Xiaotian Han, Ting Zhao, Tian Yan, Rencheng Yu
Summary: A LAMP method coupled with a LFD was developed for detecting harmful algae Karenia mikimotoi, showing high sensitivity and specificity, indicating a promising approach for detecting and monitoring harmful algal blooms.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Chemistry, Analytical
Shuya He, Yan Zhou, Yaoqi Xie, Kaijiong Zhang, Qiao He, Gang Yin, Haimin Zou, Qiongying Hu, Shilu Zhang, Hongfei He, Dongsheng Wang
Summary: Due to the complexity of detecting nucleic acids in clinical samples and the low abundance of the target, false positives caused by nonspecific amplification are common. This study presents a specific signal extract-to-output isothermal detection system (SSEI) that can detect as low as 10 copies of target DNA per reaction, overcoming the limitations of other nucleic acid isothermal amplification techniques.
Article
Chemistry, Analytical
Siwenjie Qian, Yanju Chen, Cheng Peng, Xiaofu Wang, Hui Wu, Yang Che, Huanying Wang, Junfeng Xu, Jian Wu
Summary: This article introduces a simple and cost-effective method for detecting African swine fever virus (ASFV). The method utilizes filter paper to purify nucleic acids from swine blood and employs CRISPR/Cas12a-mediated loop-mediated isothermal amplification (LAMP) reaction to detect ASFV. The method does not require complex laboratory conditions, and has the advantages of rapid and visualized detection, making it suitable for on-site application.
Article
Chemistry, Analytical
Hongbo Shan, Yang Wang, Tao Wu, Binwu Ying, Gaolian Xu
Summary: Asymmetric hairpins mediated amplification (HMA) is a novel isothermal amplification method developed for the diagnosis of Mycobacterium Tuberculosis (MTB). It has high sensitivity, specificity, and direct visualization, making it suitable for point-of-care (POC) diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Shengjun Bu, Qianyu Zhou, Liming Liu, Chunyang Zhou, Zhuo Hao, Jiayu Wan, Chunying Pang
Summary: The present study describes a novel technology called TPIA that enables target nucleic acid detection. By using specific design strategy and fluorescence techniques, this system provides a versatile tool with great potential for biomedical research and clinical diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biophysics
Ting Zheng, Xianming Li, Yanjun Si, Minjin Wang, Yuzhen Zhou, Yusheng Yang, Na Liang, Binwu Ying, Peng Wu
Summary: In this study, an accurate point-of-care testing (POCT) platform was proposed by specific recognition of target amplicons with peptide nucleic acid (PNA, assisted by T7 Exonuclease), which efficiently eliminated false positives and showed high sensitivity and specificity for detecting SARS-CoV-2.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Hao Jiang, Yuan Li, Xuefei Lv, Yulin Deng, Xiaoqiong Li
Summary: Nucleic acid amplification techniques, such as polymerase chain reaction (PCR) and isothermal amplification, are important for nucleic acid detection. However, PCR is limited by temperature control and isothermal amplification has its own limitations. Efforts to integrate enzymes and amplification techniques have the potential to overcome these limitations. This review provides a comprehensive summary of cascade amplification, including design fundamentals, signal generation, evolution, applications, challenges, and trends.
Article
Immunology
Haili Wang, Yuhang Zhang, Jingming Zhou, Ming Li, Yumei Chen, Yankai Liu, Hongliang Liu, Peiyang Ding, Chao Liang, Xifang Zhu, Ying Zhang, Cheng Xin, Gaiping Zhang, Aiping Wang
Summary: This study established a RT-RAA-LFD assay for the rapid clinical detection of HCV, which demonstrated fast, accurate, and highly specific results, making it suitable for use in communities and remote areas.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Thanawat Sridapan, Wanida Tangkawsakul, Tavan Janvilisri, Wansika Kiatpathomchai, Sirintip Dangtip, Natharin Ngamwongsatit, Duangjai Nacapricha, Puey Ounjai, Surang Chankhamhaengdecha
Summary: The combination of LAMP technology and LFB biosensor was developed for visual inspection of C. perfringens specific cpa gene, showing no cross-reactivity with other bacterial strains and a detection limit of 1-10 CFU/g sample. Compared to commercial real-time PCR kit and culture-based method, the LAMP-LFB assay demonstrated high sensitivity (88.0%), specificity (95.5%), and relative accuracy.
Article
Immunology
Jianyu Zeng, Wenlong Wang, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Yanhong Chen, Yongning Zhang, Hanchun Yang
Summary: A nucleic acid detection assay combining RT-RAA with LFD was developed for rapid and accurate detection of porcine deltacoronavirus (PDCoV). The assay exhibited good reproducibility and repeatability, and showed comparable performance to the reference method.
Article
Agriculture, Multidisciplinary
Linlin Bai, Liu Wang, Shuqin Huang, Rong Bai, Xucong Lv, Liping Sun, Fang Zhang, Xiahong Xu
Summary: In this study, we introduced CRISPR/Cas12a to specifically recognize the amplicons of NEAA and convert the signals into fluorescent readouts. The vis-NEAA method takes advantage of the high efficiency of NEAA and successfully bypasses nonspecific amplification. Compared to traditional methods, vis-NEAA is efficient, accurate, and fast, allowing for the detection of low concentrations of Salmonella in egg samples within 20 minutes.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Qi Zhang, Yibin Ying, Jianfeng Ping
Summary: Plant nanoscience is an emerging field that explores the interaction between plants and nanotechnology, leveraging nanosensors, nanofertilizers, and more to increase crop yields and address future food shortages and energy crises.
Article
Chemistry, Multidisciplinary
Tailong Cai, Lingyi Lan, Bo Peng, Chao Zhang, Shufen Dai, Chi Zhang, Jianfeng Ping, Yibin Ying
Summary: Water-enabled electricity generation technologies are attractive and renewable solutions to global energy crisis and pollution. However, current technologies still face challenges such as high cost, harmful components, and specific environmental requirements. This study presents a high-performance wood-based moisture-enabled electric generator that can offer clean energy for undeveloped and disaster-relief regions.
Article
Biophysics
Rongzhou Lin, Yunxia Jin, Renee R. Li, Chengmei Jiang, Jianfeng Ping, Christopher J. Charles, Yong Lin Kong, John S. Ho
Summary: An ultrathin bioimpedance microsensor array that can be integrated on intravenous needles is reported for early and sensitive detection of extravasation. The microsensors demonstrate high sensitivity in differentiating various intravenous solutions in different tissue layers, and can detect saline extravasation with a detection limit as low as 20 μL.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Nanoscience & Nanotechnology
Bo Peng, Xinyue Wu, Chi Zhang, Chao Zhang, Lingyi Lan, Jianfeng Ping, Yibin Ying
Summary: A self-adhesive, water-proof, and gas-permeable electrode was fabricated by in situ electrospinning of a polylactic acid nanofiber membrane (PLANFM) on a leaf, spraying a layer of the carbon nanotube membrane (CNTM) on PLANFM, and in situ electrospinning of PLANFM on CNTM. The electrodes could be self-adhered to the leaf via electrostatic adhesion and formed a capacitance sensor. The in situ fabricated electrode did not affect plant physiological parameters, and a wireless leaf capacitance sensing system was developed to detect the change of plant water status in the early stage of drought stress.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Food Science & Technology
Han Chen, Yao Yao, Chao Zhang, Jianfeng Ping
Summary: It is significant to establish effective detection methods for heavy metal pollution in infant milk powder. In this study, a screen-printed electrode (SPE) modified with nanoporous carbon (NPC) was used to detect Pb(II) and Cd(II) in infant milk powder using an electrochemical method. The use of NPC as a functional nanolayer facilitated the electrochemical detection of Pb(II) and Cd(II) due to its efficient mass transport and large adsorption capacity. The developed SPE/NPC showed the ability to detect Pb(II) and Cd(II) in milk powder based on the performance in the extracted infant milk powder.
Article
Chemistry, Analytical
Huan Zeng, Shuqin Huang, Yunong Chen, Minshi Chen, Kaiyu He, Caili Fu, Qiang Wang, Fang Zhang, Liu Wang, Xiahong Xu
Summary: A sequence-specific visualization method based on loop-mediated isothermal amplification (LAMP) was developed for the detection of Salmonella in milk. The method used restriction endonuclease and nicking endonuclease to produce amplicons into single-stranded triggers, which further promoted the generation of a G-quadruplex by a DNA machine. The G-quadruplex DNAzyme possessed peroxidase-like activity and catalyzed the color development of ABTS as the readouts. The method demonstrated a sensitivity of 800 CFU/mL when observed with the naked eye and could detect Salmonella in milk within 1.5 h without the need for any sophisticated instrument.
Review
Chemistry, Analytical
Youngung Seok, Michael G. Mauk, Ruijie Li, Cheng Qian
Summary: In resource-limited conditions like the COVID-19 pandemic, on-site detection of diseases using Point-of-care testing (POCT) is crucial for overcoming crises and saving lives. This review introduces recent approaches to respiratory virus detection, analysis trends, and prospects, emphasizing the importance of affordable, sensitive, and rapid testing on simple and portable platforms.
ANALYTICA CHIMICA ACTA
(2023)
Review
Chemistry, Analytical
Syed Muhammad Zaigham Abbas Naqvi, Yanyan Zhang, Muhammad Naveed Tahir, Zia Ullah, Shakeel Ahmed, Junfeng Wu, Vijaya Raghavan, Mukhtar Iderawumi Abdulraheem, Jianfeng Ping, Xinran Hu, Jiandong Hu
Summary: Modern methods such as spectroscopy, biosensors, and electrochemical sensors have improved the quality and sensitivity of plant hormone detection, reducing the cumbersome sample preparation process. However, the handling and sample preparations of these methods are challenging. Advanced ultrasensitive nondestructive methods show promise for long-term and biocompatible use. This review summarizes the applications, advantages, and disadvantages of different detection methods and discusses the challenges and future prospects of ultrasensitive nondestructive devices for in vivo plant hormone detection.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Analytical
Fengnian Zhao, Li Wang, Mengyue Li, Min Wang, Guangyang Liu, Jianfeng Ping
Summary: This review summarizes the research progress of nanozyme-based biosensors for OP detection in the last six years (2018-2023), discussing the structural classification, catalytic activity, and biosensing strategy. It emphatically introduces the practical applications of nanozyme-enabled biosensors in the direction of simple operation, low cost, and on-site detection, such as optical and electrochemical biosensors. Finally, it prospects the main challenges and future trends, providing theoretical references for nanozyme-based biosensors in OP detection.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Materials Science, Multidisciplinary
Shufen Dai, Xunjia Li, Chengmei Jiang, Jianfeng Ping, Yibin Ying
Summary: Triboelectric nanogenerator (TENG) efficiently harvests mechanical energy from the agricultural environment to provide distributed power for microdevice networks in smart agriculture, enabling self-powered agricultural monitoring and production strategy adjustment and further promoting agricultural production intelligence.
Article
Multidisciplinary Sciences
Chengmei Jiang, Qi Zhang, Chengxin He, Chi Zhang, Xiaohui Feng, Xunjia Li, Qiang Zhao, Yibin Ying, Jianfeng Ping
Summary: This study explores the triboelectric properties of plant proteins, which are found to possess excellent performance. By recycling and using these proteins, a biodegradable TENG is constructed and applied in agriculture with promising results.
FUNDAMENTAL RESEARCH
(2022)
Article
Engineering, Electrical & Electronic
Chao Zhang, Chi Zhang, Xinyue Wu, Jianfeng Ping, Yibin Ying
Summary: The integrated plant wearable system (IPWS) based on adaptive winding strain (AWS) sensor can provide stable and high-fidelity monitoring of plant pulse, reflecting the growth and water state of plants in real time.
NPJ FLEXIBLE ELECTRONICS
(2022)
Article
Food Science & Technology
Wei-Ling Guo, Ying-Jia Cao, Shi-Ze You, Qi Wu, Fang Zhang, Jin-Zhi Han, Xu-Cong Lv, Ping-Fan Rao, Lian-Zhong Ai, Li Ni
Summary: Ganoderma lucidum ethanol extract (GLE) has a protective effect against alcoholic liver injury by reducing abnormal lipid levels, attenuating hepatic lipid accumulation and pathological changes, ameliorating oxidative stress, regulating gut microbiota, and modulating liver metabolites and gene expression related to fatty acid metabolism, ethanol catabolism, and inflammatory response.
CURRENT RESEARCH IN FOOD SCIENCE
(2022)
Article
Food Science & Technology
Xunjia Li, Jianjun Luo, Kai Han, Xue Shi, Zewei Ren, Yi Xi, Yibin Ying, Jianfeng Ping, Zhong Lin Wang
Summary: This article introduces a wind and rain energy-driven electrical stimulation system for enhancing crop production. The system utilizes a triboelectric nanogenerator and a raindrop-driven nanogenerator, which can significantly increase the germination speed and yield of pea seeds through the self-generated high-voltage electric field. By harnessing environmental energy, the system can drive agricultural sensors to optimize plant growth.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
