First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

标题
First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes
作者
关键词
p38 kinase, Structure-based drug design, Chronic inflammatory lung disease, Kinase inhibitor, Inhibitor half-lives, Differential scanning fluorimetry
出版物
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
Volume 1860, Issue 11, Pages 2335-2344
出版商
Elsevier BV
发表日期
2016-06-30
DOI
10.1016/j.bbagen.2016.06.023

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