Metformin treatment in young children with fragile X syndrome

Metformin inhibits endothelial progenitor cell migration by decreasing matrix metalloproteinases, MMP-2 and MMP-9, via the AMPK/mTOR/autophagy pathway

(2017) Wen-Dong Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Arbaclofen in fragile X syndrome: results of phase 3 trials

(2017) Elizabeth Berry-Kravis et al.   Journal of Neurodevelopmental Disorders

Tactile Defensiveness and Impaired Adaptation of Neuronal Activity in the Fmr1 Knock-Out Mouse Model of Autism

(2017) Cynthia X. He et al.   JOURNAL OF NEUROSCIENCE

Evaluation of metformin effects in the chronic phase of spontaneous seizures in pilocarpine model of temporal lobe epilepsy

(2017) Soraya Mehrabi et al.   METABOLIC BRAIN DISEASE

Metformin ameliorates core deficits in a mouse model of fragile X syndrome

(2017) Ilse Gantois et al.   NATURE MEDICINE

Growth of Expressive Syntax in Children With Fragile X Syndrome

(2017) Rouzana Komesidou et al.   JOURNAL OF SPEECH LANGUAGE AND HEARING RESEARCH

A Randomized, Double-Blind, Placebo-Controlled Trial of Low-Dose Sertraline in Young Children With Fragile X Syndrome

(2016) Laura Greiss Hess et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Insulin signaling misregulation underlies circadian and cognitive deficits in a Drosophila fragile X model

(2016) R E Monyak et al.   MOLECULAR PSYCHIATRY

Metformin for Treatment of Overweight Induced by Atypical Antipsychotic Medication in Young People With Autism Spectrum Disorder

(2016) Evdokia Anagnostou et al.   JAMA Psychiatry

Concurrent validity of the differential ability scales, second edition with the Mullen Scales of Early Learning in young children with and without neurodevelopmental disorders

(2015) Cristan Farmer et al.   CHILD NEUROPSYCHOLOGY

Metformin protects against seizures, learning and memory impairments and oxidative damage induced by pentylenetetrazole-induced kindling in mice

(2014) Ran-ran Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome

(2013) Mary Jacena S. Leigh et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

Minocycline treatment reverses ultrasonic vocalization production deficit in a mouse model of Fragile X Syndrome

(2012) Sarah E. Rotschafer et al.   BRAIN RESEARCH

Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome

(2012) C. A. Hoeffer et al.   GENES BRAIN AND BEHAVIOR

MMP9: A novel function in synaptic plasticity

(2012) Magdalena Dziembowska et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Effect of metformin on the proliferation, migration, and MMP-2 and -9 expression of human umbilical vein endothelial cells

(2012) NILUFAR ESFAHANIAN et al.   Molecular Medicine Reports

Metformin for Obesity in Children and Adolescents: A Systematic Review

(2009) M. H. Park et al.   DIABETES CARE

Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia: A nested case-control analysis

(2008) M. Bodmer et al.   DIABETES CARE