A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity
出版年份 2019 全文链接
标题
A Mendelian randomization study of IL6 signaling in cardiovascular diseases, immune-related disorders and longevity
作者
关键词
-
出版物
npj Genomic Medicine
Volume 4, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-09-20
DOI
10.1038/s41525-019-0097-4
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Genetically Determined Levels of Circulating Cytokines and Risk of Stroke
- (2019) Marios K. Georgakis et al. CIRCULATION
- OUP accepted manuscript
- (2018) EUROPEAN HEART JOURNAL
- Evaluating the potential role of pleiotropy in Mendelian randomization studies
- (2018) Gibran Hemani et al. HUMAN MOLECULAR GENETICS
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
- (2018) Rainer Malik et al. NATURE GENETICS
- Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics
- (2018) Alvaro N. Barbeira et al. Nature Communications
- Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
- (2018) Neil M Davies et al. BMJ-British Medical Journal
- Reading Mendelian randomisation studies: a guide, glossary, and checklist for clinicians
- (2018) Neil M Davies et al. BMJ-British Medical Journal
- Genomic atlas of the human plasma proteome
- (2018) Benjamin B. Sun et al. NATURE
- Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
- (2018) Jonas B. Nielsen et al. NATURE GENETICS
- Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy
- (2018) Tianxi Cai et al. JAMA Cardiology
- The prognostic value of interleukin 6 in multiple chronic diseases and all-cause death: The Multi-Ethnic Study of Atherosclerosis (MESA)
- (2018) Miguel Cainzos-Achirica et al. ATHEROSCLEROSIS
- Low-Dose Methotrexate for the Prevention of Atherosclerotic Events
- (2018) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants
- (2017) Stephen Burgess et al. EPIDEMIOLOGY
- Safety and effectiveness of tocilizumab in treating patients with rheumatoid arthritis – A three-year study in Taiwan
- (2017) Ching-Tsai Lin et al. JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
- Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
- (2017) Manuel A Ferreira et al. NATURE GENETICS
- Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- (2017) Paul M Ridker et al. NEW ENGLAND JOURNAL OF MEDICINE
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease
- (2017) Pim van der Harst et al. CIRCULATION RESEARCH
- Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations
- (2017) Bram P. Prins et al. Scientific Reports
- Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants
- (2016) Luke C. Pilling et al. Aging-US
- LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
- (2016) Jie Zheng et al. BIOINFORMATICS
- Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk LociNovelty and Significance
- (2016) Gregory T. Jones et al. CIRCULATION RESEARCH
- IL-6 pathway in the liver: From physiopathology to therapy
- (2016) Dirk Schmidt-Arras et al. JOURNAL OF HEPATOLOGY
- Interleukin-6 and C-reactive protein and risk for death and cardiovascular events in patients with atrial fibrillation
- (2015) Julia Aulin et al. AMERICAN HEART JOURNAL
- Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors
- (2015) Stephen Burgess et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression
- (2015) J. Bowden et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease
- (2015) Majid Nikpay et al. NATURE GENETICS
- Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
- (2015) Lavinia Paternoster et al. NATURE GENETICS
- An atlas of genetic correlations across human diseases and traits
- (2015) Brendan Bulik-Sullivan et al. NATURE GENETICS
- A gene-based association method for mapping traits using reference transcriptome data
- (2015) Eric R Gamazon et al. NATURE GENETICS
- IL-6 as a keystone cytokine in health and disease
- (2015) Christopher A Hunter et al. NATURE IMMUNOLOGY
- A Variant of IL6R Is Associated with the Recurrence of Atrial Fibrillation after Catheter Ablation in a Chinese Han Population
- (2014) Gang Wu et al. PLoS One
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics
- (2014) Claudia Giambartolomei et al. PLoS Genetics
- Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data
- (2013) Stephen Burgess et al. GENETIC EPIDEMIOLOGY
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- (2013) Yukinori Okada et al. NATURE
- The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis
- (2012) LANCET
- Large-scale association analysis identifies new risk loci for coronary artery disease
- (2012) Panos Deloukas et al. NATURE GENETICS
- Large-Scale Candidate Gene Analysis in Whites and African Americans Identifies IL6R Polymorphism in Relation to Atrial Fibrillation
- (2011) Renate B. Schnabel et al. Circulation-Cardiovascular Genetics
- Identification of IL6R and chromosome 11q13.5 as risk loci for asthma
- (2011) Manuel AR Ferreira et al. LANCET
- Interleukin 6 Mediates Myocardial Fibrosis, Concentric Hypertrophy, and Diastolic Dysfunction in Rats
- (2010) Giselle C. Meléndez et al. HYPERTENSION
- Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
- (2010) Brandon L Pierce et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation