期刊
ALLERGOLOGY INTERNATIONAL
卷 69, 期 1, 页码 35-45出版社
JAPANESE SOCIETY ALLERGOLOGY
DOI: 10.1016/j.alit.2019.08.001
关键词
Allergic disease; Asthma; Exosomes; Immunomodulation; Mesenchymal stem cells
资金
- National Key R&D Program of China [2017YFA0105800]
- Natural Science Foundation of China [81670897]
- Guangdong Natural Science Funds for Distinguished Young Scholars [2016A030306006]
Allergic diseases, which include asthma, allergic skin diseases, allergic rhinitis and allergic conjunctivitis, have already garnered worldwide public health attention over recent decades. Mesenchymal stem cells (MSCs) have gradually emerged as a potential method for treating allergic diseases due to their immunosuppressive characteristics, tissue repair ability and secretion of various biological factors. This potential of MSC-based therapy has been confirmed in clinical and preclinical studies, which report the therapeutic benefits of MSCs for various allergic diseases and explore the antiallergic mechanisms. In this review, we focus on the discoveries and biological mechanisms of MSCs as a therapeutic tool in allergic diseases. We discuss the challenges of conducting MSC studies as well as future directions. Copyright (C) 2019, Japanese Society of Allergology. Production and hosting by Elsevier B.V.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据