Nrf2-Heme Oxygenase-1 Attenuates High-Glucose-Induced Epithelial-to-Mesenchymal Transition of Renal Tubule Cells by Inhibiting ROS-Mediated PI3K/Akt/GSK-3β Signaling

Concerted redox modulation by sulforaphane alleviates diabetes and cardiometabolic syndrome

(2018) Bijal Patel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Diabetes and Kidney Disease: Role of Oxidative Stress

(2016) Jay C. Jha et al.   ANTIOXIDANTS & REDOX SIGNALING

TGF-β: the connecting link between nephropathy and fibrosis

(2016) Brijesh Sutariya et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Protective role of sulphoraphane against vascular complications in diabetes

(2016) Sho-Ichi Yamagishi et al.   PHARMACEUTICAL BIOLOGY

Sulforaphane attenuation of experimental diabetic nephropathy involves GSK-3 beta/Fyn/Nrf2 signaling pathway

(2015) Guoguo Shang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of ROS-relative NF-κB signaling on high glucose-induced TLR4 and MCP-1 expression in podocyte injury

(2015) Miaomiao Wei et al.   MOLECULAR IMMUNOLOGY

Pathogenesis of Type 2 Epithelial to Mesenchymal Transition (EMT) in Renal and Hepatic Fibrosis

(2015) Anusha Tennakoon et al.   Journal of Clinical Medicine

Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?

(2015) Ivonne Loeffler et al.   Cells

Curcumin protects renal tubular epithelial cells from high glucose-induced epithelial-to-mesenchymal transition through Nrf2-mediated upregulation of heme oxygenase-1

(2015) XIULI ZHANG et al.   Molecular Medicine Reports

Epithelial–Mesenchymal Transition in Kidney Tubular Epithelial Cells Induced by Globotriaosylsphingosine and Globotriaosylceramide

(2015) Yeo Jin Jeon et al.   PLoS One

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

(2014) Zhiguo Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling

(2014) Yu Hong et al.   Journal of Translational Medicine

Lithium Chloride Suppresses Colorectal Cancer Cell Survival and Proliferation through ROS/GSK-3β/NF-κB Signaling Pathway

(2014) Huili Li et al.   Oxidative Medicine and Cellular Longevity

EGFR signaling in renal fibrosis

(2014) Shougang Zhuang et al.   Kidney International Supplements

Kick it up a notch: Notch signaling and kidney fibrosis

(2014) Mariya T. Sweetwyne et al.   Kidney International Supplements

Wnt/β-catenin signaling and kidney fibrosis

(2014) Roderick J. Tan et al.   Kidney International Supplements

Keap1-Nrf2 signaling pathway: Mechanisms of regulation and role in protection of cells against toxicity caused by xenobiotics and electrophiles

(2013) K. T. Turpaev   BIOCHEMISTRY-MOSCOW

Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes

(2013) Gopal V. Velmurugan et al.   CARDIOVASCULAR RESEARCH

Hedgehog-Gli Pathway Activation during Kidney Fibrosis

(2012) Steven L. Fabian et al.   AMERICAN JOURNAL OF PATHOLOGY

TGFβ modulates cell-to-cell communication in early epithelial-to-mesenchymal transition

(2012) C. E. Hills et al.   DIABETOLOGIA

Diabetes-Induced Hepatic Pathogenic Damage, Inflammation, Oxidative Stress, and Insulin Resistance Was Exacerbated in Zinc Deficient Mouse Model

(2012) Chi Zhang et al.   PLoS One

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes

(2011) Milad S. Bitar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications

(2011) Young-Sam Keum   Annals of the New York Academy of Sciences

The cytoprotective role of the Keap1–Nrf2 pathway

(2011) Liam Baird et al.   ARCHIVES OF TOXICOLOGY

The role of EMT in renal fibrosis

(2011) Rosemarie M. Carew et al.   CELL AND TISSUE RESEARCH

Activation of NF-E2-Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

(2008) M. Xue et al.   DIABETES