Identifying the active components of Baihe–Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests

Enhanced Anti-diabetic Effect of Berberine Combined With Timosaponin B2 in Goto-Kakizaki Rats, Associated With Increased Variety and Exposure of Effective Substances Through Intestinal Absorption

(2019) Xiaoting Tian et al.   Frontiers in Pharmacology

Antidiabetic effect of mangiferin in combination with oral hypoglycemic agents metformin and gliclazide

(2019) Vidhushini Sekar et al.   PHYTOMEDICINE

Involvement of Hepatic SHIP2 and PI3K/Akt Signalling in the Regulation of Plasma Insulin by Xiaoyaosan in Chronic Immobilization-Stressed Rats

(2019) Qiuxia Pan et al.   MOLECULES

Exploration of the hepatoprotective chemical base of an orally administered herbal formulation (YCHT) in normal and CCl4-intoxicated liver injury rats. Part 2: Hepatic disposition in vivo and hepatoprotective activity in vitro

(2019) Xiaoting Tian et al.   JOURNAL OF ETHNOPHARMACOLOGY

Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity

(2018) Yang Xie et al.   ACTA PHARMACOLOGICA SINICA

Protective effects of timosaponin BII on oxidative stress damage in PC12 cells based on metabolomics

(2018) Qinmei Xie et al.   BIOMEDICAL CHROMATOGRAPHY

Pharmacokinetics-Based Identification of Potential Therapeutic Phthalides from XueBiJing, a Chinese Herbal Injection Used in Sepsis Management

(2018) Nating Zhang et al.   DRUG METABOLISM AND DISPOSITION

Simultaneous determination of eight bioactive compounds by LC-MS/MS and its application to the pharmacokinetics, liver first-pass effect, liver and brain distribution of orally administrated Gouteng - Baitouweng (GB) in rats

(2018) Xiaoting Tian et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Pharmacokinetic comparison of seven major bioactive components in normal and depression model rats after oral administration of Baihe Zhimu decoction by liquid chromatography–tandem mass spectrometry

(2018) Bo Yang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Genes Linking Mitochondrial Function, Cognitive Impairment and Depression are Associated with Endophenotypes Serving Precision Medicine

(2018) Peter Petschner et al.   NEUROSCIENCE

Antidepressant-Like Effects of Cistanche tubulosa Extract on Chronic Unpredictable Stress Rats Through Restoration of Gut Microbiota Homeostasis

(2018) Yang Li et al.   Frontiers in Pharmacology

Molecular Mechanisms Underlying the Anti-depressant Effects of Resveratrol: a Review

(2017) Marcos Roberto de Oliveira et al.   MOLECULAR NEUROBIOLOGY

Timosaponin B-III exhibits antidepressive activity in a mouse model of postpartum depression by the regulation of inflammatory cytokines, BNDF signaling and synaptic plasticity

(2017) Xiao-Li Zhang et al.   Experimental and Therapeutic Medicine

Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effectin vitroandin vivo

(2016) Xiaoting Tian et al.   BIOFACTORS

The rapid antidepressant and anxiolytic-like effects of YY-21 involve enhancement of excitatory synaptic transmission via activation of mTOR signaling in the mPFC

(2016) Fei Guo et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Metabonomic identification of the effects of the Zhimu-Baihe saponins on a chronic unpredictable mild stress-induced rat model of depression

(2016) Hongli Du et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Inflammation Effects on Motivation and Motor Activity: Role of Dopamine

(2016) Jennifer C Felger et al.   NEUROPSYCHOPHARMACOLOGY

Timosaponin derivative YY-23 acts as a non-competitive NMDA receptor antagonist and exerts a rapid antidepressant-like effect in mice

(2015) Qi Zhang et al.   ACTA PHARMACOLOGICA SINICA

Comparison between herbal medicine and fluoxetine for depression: A systematic review of randomized controlled trials

(2015) Yi Ren et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Simultaneous Determination of Five Components in Rat Plasma by UPLC–MS/MS and Its Application to a Comparative Pharmacokinetic Study in Baihe Zhimu Tang and Zhimu Extract

(2015) Guolong Li et al.   MOLECULES

A systematic review on the efficacy, safety and types of Chinese herbal medicine for depression

(2014) Wing-Fai Yeung et al.   JOURNAL OF PSYCHIATRIC RESEARCH

The best way forward

(2014) Lisa M. Monteggia et al.   NATURE

Characterization and Identification of Major Constituents in Baihe Zhimu Decoction by HPLC-MSn

(2013)   ASIAN JOURNAL OF CHEMISTRY

Determination of mangiferin in rat plasma by liquid–liquid extraction with UPLC–MS/MS

(2009) Dandan Han et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation: Report of the European Consensus Conference

(2009) Pierre Wallemacq et al.   THERAPEUTIC DRUG MONITORING