Is AD a Stress-Related Disorder? Focus on the HPA Axis and Its Promising Therapeutic Targets
出版年份 2019 全文链接
标题
Is AD a Stress-Related Disorder? Focus on the HPA Axis and Its Promising Therapeutic Targets
作者
关键词
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出版物
Frontiers in Aging Neuroscience
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-09-27
DOI
10.3389/fnagi.2019.00269
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Corticosteroid action in the brain: the potential of selective receptor modulation
- (2019) Eva Viho et al. NEUROENDOCRINOLOGY
- Pathophysiology of Glucocorticoid Signaling
- (2018) Géraldine Vitellius et al. ANNALES D ENDOCRINOLOGIE
- Glucocorticoid receptor modulators
- (2018) Onno C. Meijer et al. ANNALES D ENDOCRINOLOGIE
- Differential effects of imipramine and CORT118335 (Glucocorticoid receptor modulator/mineralocorticoid receptor antagonist) on brain-endocrine stress responses and depression-like behavior in female rats
- (2018) Elizabeth T. Nguyen et al. BEHAVIOURAL BRAIN RESEARCH
- Glucocorticoid may influence amyloid β metabolism in patients with depression
- (2018) Satoko Ishijima et al. PSYCHIATRY RESEARCH
- Corticotrophin releasing factor receptor 1 antagonists prevent chronic stress-induced behavioral changes and synapse loss in aged rats
- (2018) Hongxin Dong et al. PSYCHONEUROENDOCRINOLOGY
- Increased Tau Phosphorylation and Aggregation in the Hippocampus of Mice Overexpressing Corticotropin-Releasing Factor
- (2018) Shannon N. Campbell et al. JOURNAL OF ALZHEIMERS DISEASE
- Oxytocin and vasopressin in the rodent hippocampus
- (2018) Nicholas I. Cilz et al. GENES BRAIN AND BEHAVIOR
- Central Role of Glucocorticoid Receptors in Alzheimer’s Disease and Depression
- (2018) Geoffrey Canet et al. Frontiers in Neuroscience
- Forced swimming-induced oxytocin release into blood and brain: Effects of adrenalectomy and corticosterone treatment
- (2017) Luz Torner et al. PSYCHONEUROENDOCRINOLOGY
- Don’t stress about CRF: assessing the translational failures of CRF1antagonists
- (2017) Samantha R. Spierling et al. PSYCHOPHARMACOLOGY
- Hypothalamic-pituitary-adrenal axis and depression symptom effects of an arginine vasopressin type 1B receptor antagonist in a one-week randomized Phase 1b trial
- (2017) David A. Katz et al. Brain and Behavior
- Corticotropin-releasing factor receptor-1 antagonism mitigates beta amyloid pathology and cognitive and synaptic deficits in a mouse model of Alzheimer's disease
- (2016) Cheng Zhang et al. Alzheimers & Dementia
- Chronic mild stress accelerates the progression of Parkinson's disease in A53T α-synuclein transgenic mice
- (2016) Qimei Wu et al. EXPERIMENTAL NEUROLOGY
- Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?
- (2016) Joe Herbert et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Purported Interactions of Amyloid-β and Glucocorticoids in Cytotoxicity and Genotoxicity: Implications in Alzheimer’s Disease
- (2016) Xabier Bengoetxea et al. JOURNAL OF ALZHEIMERS DISEASE
- New selective glucocorticoid receptor modulators reverse amyloid-β peptide–induced hippocampus toxicity
- (2016) Fanny Pineau et al. NEUROBIOLOGY OF AGING
- A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence
- (2016) Megan L Ryan et al. NEUROPSYCHOPHARMACOLOGY
- Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration
- (2016) Sheela Vyas et al. NEURAL PLASTICITY
- Mechanisms of rapid glucocorticoid feedback inhibition of the hypothalamic–pituitary–adrenal axis
- (2016) Jeffrey G. Tasker et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- Systemic and intrahippocampal administrations of the glucocorticoid receptor antagonist RU38486 impairs fear memory reconsolidation in rats
- (2016) Saeed Nikzad et al. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
- 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile
- (2015) Hazel J. Hunt et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease
- (2015) Karen Sooy et al. ENDOCRINOLOGY
- A Mixed Glucocorticoid/Mineralocorticoid Selective Modulator With Dominant Antagonism in the Male Rat Brain
- (2015) Erika Atucha et al. ENDOCRINOLOGY
- Neuromodulatory signaling in hippocampus-dependent memory retrieval
- (2015) Steven A. Thomas HIPPOCAMPUS
- Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice
- (2015) Joyce L.W. Yau et al. NEUROBIOLOGY OF AGING
- Tau as the Converging Protein between Chronic Stress and Alzheimer's Disease Synaptic Pathology
- (2015) Ioannis Sotiropoulos et al. Neurodegenerative Diseases
- Clinical safety and hypothalamic-pituitary-adrenal axis effects of the arginine vasopressin type 1B receptor antagonist ABT-436
- (2015) David A. Katz et al. PSYCHOPHARMACOLOGY
- Antidepressant and anxiolytic profiles of newly synthesized arginine vasopressin V1Breceptor antagonists: TASP0233278 and TASP0390325
- (2014) M Iijima et al. BRITISH JOURNAL OF PHARMACOLOGY
- The selective glucocorticoid receptor antagonist CORT 108297 decreases neuroendocrine stress responses and immobility in the forced swim test
- (2014) Matia B. Solomon et al. HORMONES AND BEHAVIOR
- The selective glucocorticoid receptor modulator CORT108297 restores faulty hippocampal parameters in Wobbler and corticosterone-treated mice
- (2014) Maria Meyer et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2
- (2014) J H Pagani et al. MOLECULAR PSYCHIATRY
- Effects of Selective and Non-Selective Glucocorticoid Receptor II Antagonists on Rapid-Onset Diabetes in Young Rats
- (2014) Jacqueline L. Beaudry et al. PLoS One
- Effects of corticotrophin-releasing factor receptor 1 antagonists on amyloid-β and behavior in Tg2576 mice
- (2014) Hongxin Dong et al. PSYCHOPHARMACOLOGY
- Mifepristone Alters Amyloid Precursor Protein Processing to Preclude Amyloid Beta and Also Reduces Tau Pathology
- (2013) David Baglietto-Vargas et al. BIOLOGICAL PSYCHIATRY
- Hypercortisolemia and Glucocorticoid Receptor-Signaling Insufficiency in Alzheimer’ s Disease Initiation and Development
- (2013) Elena Notarianni Current Alzheimer Research
- The glucocorticoid receptors regulation in Alzheimer's disease
- (2013) Laurent Givalois NEUROBIOLOGY OF AGING
- Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator
- (2013) I. Zalachoras et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deregulation of hypothalamic-pituitary-adrenal axis functions in an Alzheimer's disease rat model
- (2012) Anthony Brureau et al. NEUROBIOLOGY OF AGING
- Tumor Necrosis Factor Inhibits Glucocorticoid Receptor Function in Mice
- (2011) Tom Van Bogaert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Administration of a selective glucocorticoid antagonist attenuates electroconvulsive shock-induced retrograde amnesia
- (2011) Chittaranjan Andrade et al. JOURNAL OF NEURAL TRANSMISSION
- Chronic Stress Exacerbates Tau Pathology, Neurodegeneration, and Cognitive Performance through a Corticotropin-Releasing Factor Receptor-Dependent Mechanism in a Transgenic Mouse Model of Tauopathy
- (2011) J. C. Carroll et al. JOURNAL OF NEUROSCIENCE
- Acute Inhibition of 11 -Hydroxysteroid Dehydrogenase Type-1 Improves Memory in Rodent Models of Cognition
- (2011) E. G. Mohler et al. JOURNAL OF NEUROSCIENCE
- Progress in corticotropin-releasing factor-1 antagonist development
- (2010) Eric P. Zorrilla et al. DRUG DISCOVERY TODAY
- Partial Deficiency or Short-Term Inhibition of 11 -Hydroxysteroid Dehydrogenase Type 1 Improves Cognitive Function in Aging Mice
- (2010) K. Sooy et al. JOURNAL OF NEUROSCIENCE
- The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
- (2010) Agnes E. Coutinho et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Alzheimer's Disease
- (2010) Henry W. Querfurth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glucocorticoids in the prefrontal cortex enhance memory consolidation and impair working memory by a common neural mechanism
- (2010) A. Barsegyan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective glucocorticoid receptor (type II) antagonist prevents and reverses olanzapine-induced weight gain
- (2009) J. K. Belanoff et al. DIABETES OBESITY & METABOLISM
- Oxytocin: The Great Facilitator of Life
- (2009) Heon-Jin Lee et al. PROGRESS IN NEUROBIOLOGY
- 1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activity
- (2008) Robin D. Clark et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators
- (2008) Bruce S. McEwen EUROPEAN JOURNAL OF PHARMACOLOGY
- Corticosterone and related receptor expression are associated with increased β-amyloid plaques in isolated Tg2576 mice
- (2008) H. Dong et al. NEUROSCIENCE
- Vasopressin: Behavioral roles of an “original” neuropeptide
- (2007) Heather K. Caldwell et al. PROGRESS IN NEUROBIOLOGY
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