Metadherin enhances vulnerability of cancer cells to ferroptosis

Activation of EMT in colorectal cancer by MTDH/NF-κB p65 pathway

(2019) Nahla E. El-Ashmawy et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CCL18 promotes the metastasis of squamous cell carcinoma of the head and neck through MTDH-NF-κB signalling pathway

(2019) Yuexiang Qin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Pembrolizumab plus Chemotherapy in Metastatic Non–Small-Cell Lung Cancer

(2018) Leena Gandhi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oncoprotein AEG-1 is an endoplasmic reticulum RNA-binding protein whose interactome is enriched in organelle resident protein-encoding mRNAs

(2018) Jack C.-C. Hsu et al.   RNA

AZD1775 Increases Sensitivity to Olaparib and Gemcitabine in Cancer Cells with p53 Mutations

(2018) Xiangbing Meng et al.   Cancers

Pembrolizumab plus Chemotherapy for Squamous Non–Small-Cell Lung Cancer

(2018) Luis Paz-Ares et al.   NEW ENGLAND JOURNAL OF MEDICINE

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility

(2017) Chun-Shik Shin et al.   Nature Communications

Inverse Relationship between Progesterone Receptor and Myc in Endometrial Cancer

(2016) Tamar Kavlashvili et al.   PLoS One

Intratumoral injection of a CpG oligonucleotide reverts resistance to PD-1 blockade by expanding multifunctional CD8+T cells

(2016) Shu Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer

(2015) Y. Liang et al.   CANCER RESEARCH

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

AEG-1 participates in TGF-beta1-induced EMT through p38 MAPK activation

(2013) Jiali Wei et al.   CELL BIOLOGY INTERNATIONAL

Glutathione peroxidases

(2012) Regina Brigelius-Flohé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition

(2011) K. Zhu et al.   CLINICAL CANCER RESEARCH

Enhancement of Carboplatin-Mediated Lung Cancer Cell Killing by Simultaneous Disruption of Glutathione and Thioredoxin Metabolism

(2011) M. A. Fath et al.   CLINICAL CANCER RESEARCH

Cytoplasmic Metadherin (MTDH) Provides Survival Advantage under Conditions of Stress by Acting as RNA-binding Protein

(2011) Xiangbing Meng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Knockdown of MTDH Sensitizes Endometrial Cancer Cells to Cell Death Induction by Death Receptor Ligand TRAIL and HDAC Inhibitor LBH589 Co-Treatment

(2011) Xiangbing Meng et al.   PLoS One

MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer

(2009) Guohong Hu et al.   CANCER CELL

The Multifaceted Role of MTDH/AEG-1 in Cancer Progression

(2009) G. Hu et al.   CLINICAL CANCER RESEARCH

Knockdown of astrocyte elevated gene-1 inhibits proliferation and enhancing chemo-sensitivity to cisplatin or doxorubicin in neuroblastoma cells

(2009) Haiyan Liu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Over-expression of AEG-1 significantly associates with tumour aggressiveness and poor prognosis in human non-small cell lung cancer

(2009) Libing Song et al.   JOURNAL OF PATHOLOGY

Identification of genes conferring resistance to 5-fluorouracil

(2009) B. K. Yoo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA