Nuclear localization signal in TRIM22 is essential for inhibition of type 2 porcine reproductive and respiratory syndrome virus replication in MARC-145 cells

The interferon-stimulated gene TRIM22 : A double-edged sword in HIV-1 infection

(2018) Elisa Vicenzi et al.   CYTOKINE & GROWTH FACTOR REVIEWS

TRIM22 regulates macrophage autophagy and enhances Mycobacterium tuberculosis clearance by targeting the nuclear factor-multiplicity κB/beclin 1 pathway

(2018) Jun Lou et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Conserved structural and functional aspects of the tripartite motif gene family point towards therapeutic applications in multiple diseases

(2018) Liubov V. Gushchina et al.   PHARMACOLOGY & THERAPEUTICS

Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009

(2018) Isabel Pagani et al.   mSphere

MOV10 inhibits replication of porcine reproductive and respiratory syndrome virus by retaining viral nucleocapsid protein in the cytoplasm of Marc-145 cells

(2018) Kuan Zhao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Resistance to coronavirus infection in amino peptidase N-deficient pigs

(2018) Kristin M. Whitworth et al.   TRANSGENIC RESEARCH

The integrity of PRRSV nucleocapsid protein is necessary for up-regulation of optimal interleukin-10 through NF-κB and p38 MAPK pathways in porcine alveolar macrophages

(2017) Jiang Yu et al.   MICROBIAL PATHOGENESIS

Interaction of porcine reproductive and respiratory syndrome virus proteins with SUMO-conjugating enzyme reveals the SUMOylation of nucleocapsid protein

(2017) Cong Wang et al.   PLoS One

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Novel insights into host responses and reproductive pathophysiology of porcine reproductive and respiratory syndrome caused by PRRSV-2

(2017) John C.S. Harding et al.   VETERINARY MICROBIOLOGY

The viral innate immune antagonism and an alternative vaccine design for PRRS virus

(2017) Hanzhong Ke et al.   VETERINARY MICROBIOLOGY

GP5 of porcine reproductive and respiratory syndrome virus (PRRSV) as a target for homologous and broadly neutralizing antibodies

(2017) Luca N. Popescu et al.   VETERINARY MICROBIOLOGY

Mechanisms of Adaptive Immunity to Porcine Reproductive and Respiratory Syndrome Virus

(2017) Michael Rahe et al.   Viruses-Basel

TRIM22-Mediated Apoptosis is Associated with Bak Oligomerization in Monocytes

(2017) Chi Chen et al.   Scientific Reports

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

(2017) Christine Burkard et al.   PLoS Pathogens

DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection

(2017) Huiyuan Jing et al.   Frontiers in Immunology

Increased Neutralizing Antibody Production and Interferon-γ Secretion in Response to Porcine Reproductive and Respiratory Syndrome Virus Immunization in Genetically Modified Pigs

(2017) Guangping Huang et al.   Frontiers in Immunology

TRIM-directed selective autophagy regulates immune activation

(2016) Tomonori Kimura et al.   Autophagy

Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease

(2016) Qi Li et al.   GASTROENTEROLOGY

The Interferon-Induced Mx2 Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication

(2016) Haiyan Wang et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Quantitative interactome reveals that porcine reproductive and respiratory syndrome virus nonstructural protein 2 forms a complex with viral nucleocapsid protein and cellular vimentin

(2016) Tao Song et al.   Journal of Proteomics

The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis

(2016) Baoming Liu et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Interacts with Nsp9 and Cellular DHX9 To Regulate Viral RNA Synthesis

(2016) Long Liu et al.   JOURNAL OF VIROLOGY

Nonstructural Protein 4 of Porcine Reproductive and Respiratory Syndrome Virus Modulates Cell Surface Swine Leukocyte Antigen Class I Expression by Downregulating β2-Microglobulin Transcription

(2016) Pengfei Qi et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus nsp1α Inhibits NF-κB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex

(2016) Huiyuan Jing et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus (PRRSV): Pathogenesis and Interaction with the Immune System

(2016) Joan K. Lunney et al.   Annual Review of Animal Biosciences

Interferon alpha (IFNα)-induced TRIM22 interrupts HCV replication by ubiquitinating NS5A

(2015) Chen Yang et al.   Cellular & Molecular Immunology

The N-N non-covalent domain of the nucleocapsid protein of type 2 porcine reproductive and respiratory syndrome virus enhances induction of IL-10 expression

(2015) Xing Liu et al.   JOURNAL OF GENERAL VIROLOGY

Control of FoxO4 Activity and Cell Survival by TRIM22 Directs TLR3-Stimulated Cells Toward IFN Type I Gene Induction or Apoptosis

(2015) Alexandra Oteiza et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter

(2015) Filippo Turrini et al.   Retrovirology

Live porcine reproductive and respiratory syndrome virus vaccines: Current status and future direction

(2015) Gourapura J. Renukaradhya et al.   VACCINE

Innate and adaptive immunity against Porcine Reproductive and Respiratory Syndrome Virus

(2015) Crystal L. Loving et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Inhibition of highly pathogenic porcine reproductive and respiratory syndrome virus replication by recombinant pseudorabies virus-mediated RNA interference in piglets

(2015) Su-fang Cao et al.   VETERINARY MICROBIOLOGY

An SH3 binding motif within the nucleocapsid protein of porcine reproductive and respiratory syndrome virus interacts with the host cellular signaling proteins STAMI, TXK, Fyn, Hck, and cortactin

(2015) Scott P. Kenney et al.   VIRUS RESEARCH

Nucleocytoplasmic transport of nucleocapsid proteins of enveloped RNA viruses

(2015) Wahyu N. Wulan et al.   Frontiers in Microbiology

The 15N and 46R Residues of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Nucleocapsid Protein Enhance Regulatory T Lymphocytes Proliferation

(2015) Baochao Fan et al.   PLoS One

TRIM22 can activate the noncanonical NF-κB pathway by affecting IKKα

(2014) Hui Qiu et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Overlapping and Distinct Molecular Determinants Dictating the Antiviral Activities of TRIM56 against Flaviviruses and Coronavirus

(2014) B. Liu et al.   JOURNAL OF VIROLOGY

TRIM5  and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment

(2014) R. Singh et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 4 Antagonizes Beta Interferon Expression by Targeting the NF- B Essential Modulator

(2014) C. Huang et al.   JOURNAL OF VIROLOGY

Porcine reproductive and respiratory syndrome virus infection activates NOD2–RIP2 signal pathway in MARC-145 cells

(2014) Huiyuan Jing et al.   VIROLOGY

Arterivirus molecular biology and pathogenesis

(2013) E. J. Snijder et al.   JOURNAL OF GENERAL VIROLOGY

Induction of TRIM22 by IFN-γ Involves JAK and PC-PLC/PKC, but Not MAPKs and pI3K/Akt/mTOR Pathways

(2013) Bo Gao et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

TRIM22 Inhibits Influenza A Virus Infection by Targeting the Viral Nucleoprotein for Degradation

(2013) A. Di Pietro et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nsp1  Inhibits Interferon-Activated JAK/STAT Signal Transduction by Inducing Karyopherin- 1 Degradation

(2013) R. Wang et al.   JOURNAL OF VIROLOGY

TRIM22 inhibits the TRAF6-stimulated NF-κB pathway by targeting TAB2 for degradation

(2013) Hui Qiu et al.   VIROLOGICA SINICA

Poly(A)-binding protein interacts with the nucleocapsid protein of porcine reproductive and respiratory syndrome virus and participates in viral replication

(2012) Xiaoye Wang et al.   ANTIVIRAL RESEARCH

Role of porcine reproductive and respiratory syndrome virus nucleocapsid protein in induction of interleukin-10 and regulatory T-lymphocytes (Treg)

(2012) P. Wongyanin et al.   JOURNAL OF GENERAL VIROLOGY

Disulfide Linkages Mediating Nucleocapsid Protein Dimerization Are Not Required for Porcine Arterivirus Infectivity

(2012) Rong Zhang et al.   JOURNAL OF VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Induces Interleukin-15 through the NF- B Signaling Pathway

(2012) Y. Fu et al.   JOURNAL OF VIROLOGY

Interplay between Interferon-Mediated Innate Immunity and Porcine Reproductive and Respiratory Syndrome Virus

(2012) Yan Sun et al.   Viruses-Basel

Identification of tripartite motif-containing 22 (TRIM22) as a novel NF-κB activator

(2011) Shanshan Yu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRIM22 Inhibits HIV-1 Transcription Independently of Its E3 Ubiquitin Ligase Activity, Tat, and NF- B-Responsive Long Terminal Repeat Elements

(2011) A. Kajaste-Rudnitski et al.   JOURNAL OF VIROLOGY

Dynamic localization of tripartite motif-containing 22 in nuclear and nucleolar bodies

(2009) Gayathri Sivaramakrishnan et al.   EXPERIMENTAL CELL RESEARCH

B30.2/SPRY domain in tripartite motif-containing 22 is essential for the formation of distinct nuclear bodies

(2009) Gayathri Sivaramakrishnan et al.   FEBS LETTERS

Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain

(2009) Bo Gao et al.   HEPATOLOGY

TRIM22 E3 ubiquitin ligase activity is required to mediate antiviral activity against encephalomyocarditis virus

(2009) P. Eldin et al.   JOURNAL OF GENERAL VIROLOGY

Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1  Modulates Host Innate Immune Response by Antagonizing IRF3 Activation

(2009) L. K. Beura et al.   JOURNAL OF VIROLOGY

Interaction of the porcine reproductive and respiratory syndrome virus nucleocapsid protein with the inhibitor of MyoD family-a domain-containing protein

(2008) Cheng Song et al.   BIOLOGICAL CHEMISTRY

The Interferon Response Inhibits HIV Particle Production by Induction of TRIM22

(2008) Stephen D. Barr et al.   PLoS Pathogens