Article
Chemistry, Analytical
Jhonys M. Freitas, Pablo R. L. Silva, Rodrigo A. A. Munoz, Eduardo M. Richter
Summary: This study developed a fast method for detecting ephedrine and demonstrated its potential value in various applications, such as criminal forensic analysis and anti-doping control. The portable nature of the method and the ability to quantify ephedrine in representative samples without pre-treatment make it a promising tool for weight-loss product adulteration detection.
MICROCHEMICAL JOURNAL
(2021)
Article
Engineering, Chemical
Kaihan Yang, Jun Yin, Tingting Zhu, Bin Liu, Guangchao Li, Bofan Huang, Zhou Shi, Lin Deng
Summary: The study suggests that using BDD electrode for electrochemical oxidation pretreatment can effectively improve the removal efficiency of dissolved organic matters and reduce the formation potential of membrane fouling.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Plant Sciences
Amany H. A. Abeed, Suzan A. Tammam, M. T. El-Mahdy
Summary: This study examined the effect of exogenous hydrogen peroxide (H2O2) on the phytoremediation capacity of J. acutus for SDS. The results showed that H2O2 enhanced the uptake and accumulation of SDS by J. acutus, and reduced the concentration of SDS in the culture media.
Article
Chemistry, Analytical
Martijn Eikelboom, Yaxuan Wang, Gemma Portlock, Arthur Gourain, Joseph Gardner, Jay Bullen, Paul Lewtas, Matthieu Carriere, Alexandra Alvarez, Arun Kumar, Shane O'Prey, Tamas Tolgyes, Dario Omanovic, Subhamoy Bhowmick, Dominik Weiss, Pascal Salaun
Summary: The voltammetric determination of total inorganic arsenic in near-neutral pH conditions using a new commercially available 25 μm diameter gold microwire was presented. The method has better analytical parameters than previous methods and is easier to implement, enabling cheaper groundwater surveying campaigns with in-the-field analysis for quick data reporting, even in remote communities.
ANALYTICA CHIMICA ACTA
(2023)
Article
Electrochemistry
Domen Obrez, Mitja Kolar, Nikola Tasic, Samo B. Hocevar
Summary: Copper electrodes have interesting characteristics for electrochemical stripping analysis and can be an alternative to mercury electrodes. Different types of copper-based electrodes were studied for the detection of trace metal ions. Most of the copper electrodes showed favorable performances for stripping voltammetry.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Martin O. A. Pacheco-Alvarez, Oracio Serrano-Torres, Abudukeremu Kadier, Enric Brillas, Juan M. Peralta-Hernandez
Summary: This paper presents the use of advanced oxidation electrochemical processes, including anodic oxidation, electroFenton, and photoelectro-Fenton, to degrade the azo dye Reactive Orange 84. Boron-doped diamond electrodes were used in different configurations in a stirred tank cell. The effects of different operating parameters, such as electrolyte concentration and applied current density, on the discoloration process were evaluated. The production of free radicals and the decrease in chemical oxygen demand were analyzed, along with the quantification of oxalic acid as a final product.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Electrochemistry
Gabriela Kuchtova, Lucia Hojova, Andrea Vojs Stanova, Marian Marton, Martin Vrska, Miroslav Behul, Pavol Michniak, Marian Vojs, Libor Dusek
Summary: The study focused on different boron-doped diamond electrodes and their application in treating water containing azo dye Direct Red 80 with chlorides, sulfates, and both. The degradation process was proposed based on the identification of degradation products and determination of adsorbable organically bound halogens. The results showed that structured silicon contributed to surface enlargement and the flow-through electrode had the highest removal rate with the lowest energy consumption. Over 95% decolorization was achieved in 60 minutes on all electrodes.
ELECTROCHIMICA ACTA
(2023)
Review
Electrochemistry
Gul S. Ustabasi, Mustafa Ozcan, Ismail Yilmaz
Summary: Determining heavy metals remains important due to contamination and industrial activities. Spectrometric methods are accurate but costly and time-consuming. Recent advancements in electrochemistry, especially voltammetric methods, have made trace-level heavy metal analysis easier, faster, and cheaper. Carbon-based electrodes, like the four most common ones examined in this review, show promise in improving performance for heavy metal determination.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Chemistry, Analytical
Adam Morris, Nuria Serrano, Jose Manuel Diaz-Cruz, Avi Bendavid, Miao Chen, Mikko Vepsalainen
Summary: The study demonstrated the superior performance of a vibrating boron-doped diamond electrode in combination with the ASV method for the analysis of ultralow concentrations of Cd(II) in water, without the need for surface modification or regular replacement of the electrode, making it suitable for on-site and online heavy metal analysis.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
Gul Sirin Ustabasi, Ismail Yilmaz, Mustafa Ozcan, Ebru Cetinkaya
Summary: Pencil graphite electrode modified with MWCNT and Bi3+ showed improved sensitivity and reduced charge transfer resistance in the simultaneous analysis of Pb2+, Cd2+, and Zn2+. This modification method offers effective electroanalytical performance with low time consumption and cost.
Article
Electrochemistry
N. M. Omar, E. M. Mabrouk, A. Y. El-Etre, A. I. Ali, A. M. Beltagi
Summary: Due to their affordability and availability, pencil graphite electrodes (PGE) have gained popularity in electrochemical applications. A disposable modified PGE sensor based on electropolymerization was developed and showed enhanced sensitivity and lower resistivity. This sensor was successfully used for sensitive and selective determination of flufenamic acid (FFA), exhibiting good accuracy, repeatability, storage stability, and selectivity.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Ricardo F. Brocenschi, Kallyni Irikura, Naihara Wachter, Greg M. Swain, Romeu C. Rocha-Filho
Summary: This study reports on the electropolishing of boron-doped diamond (BDD) electrodes in the presence of acetic and sulfuric acid. The electropolishing treatment resulted in a smoother diamond surface with reduced non-diamond carbon impurity content and increased surface oxygen content. The combination of electropolishing and cathodic pretreatment further decreased the surface oxygen content and improved the electrochemical reversibility and electron-transfer kinetics of the BDD electrodes. Electropolished BDD electrodes also exhibited a higher oxidation peak potential for ascorbic acid compared to as-received BDD electrodes, indicating a decrease in surface carbon-oxygen functional groups.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Chemistry, Analytical
Mohammad Reza Jalali Sarvestani, Tayyebeh Madrakian, Abbas Afkhami
Summary: In this study, a highly sensitive electrochemical sensor was developed for the detection of ultra-trace levels of Pb2+. The sensor was modified with an in-situ electroplated bismuth film and a nanocomposite of a recently synthesized melamine based covalent organic framework and Fe3O4 nanoparticles. The combination of Fe3O4@SNW1 and the bismuth film significantly enhanced the sensitivity of the sensor towards Pb2+. The optimized sensor showed a linear response in the concentration range of 0.003-0.3 μmol L-1 with a detection limit of 0.95 nmol L-1. The sensor demonstrated good selectivity towards Pb2+ and was successfully applied for the determination of Pb2+ in different edible specimens.
Article
Chemistry, Analytical
Dhesmon Lima, Christiana Andrade Pessoa, Karen Wohnrath, Luiz Humberto Marcolino-Junior, Marcio Fernando Bergamini
Summary: This study presents an effective voltammetric sensor for detecting tryptophan in commercial dietary supplements. The sensor was modified with poly(L-arginine) and showed improved electrochemical properties, leading to enhanced sensitivity towards tryptophan. The sensor was able to accurately detect tryptophan in a concentration range of 1.0 to 7.0 mu mol L-1.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Applied
Chong-Chong Wang, Zhen Yang, Xiao-Na Guo, Ke-Xue Zhu
Summary: The addition of IDF and FA increased the hardness and decreased the specific volume of steamed bread, promoting gluten aggregation. Specifically, FA played a significant role in promoting gluten aggregation, which may be the main reason for the deterioration of steamed bread quality.
Article
Chemistry, Physical
Saadi Ali Hoshyar, Hemn A. H. Barzani, Yavuz Yardim, Zuhre Senturk
Summary: This study investigates the impact of CTAB on the adsorption capability of BDD electrode for sensing BPA and HQ, revealing an increased sensitivity in strong acidic media with the presence of CTAB, especially for BPA. Utilizing square-wave stripping mode after an accumulation process, the limit of detections for BPA and HQ were found to be 0.05 μg/mL and 0.23 μg/mL, respectively, suggesting a potential alternative to chemically modified electrodes for environmental sample analysis.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Substance Abuse
Oruc Yunusoglu
Summary: Linalool has therapeutic effects on the rewarding properties of alcohol in mice, reducing acquisition and reinstatement and precipitating extinction of alcohol-induced conditioned place preference. Further investigation is needed to fully explore the benefits and possible adverse effects of linalool on alcohol addiction.
Article
Chemistry, Analytical
Hande Izem Ozok, Shabnam Allahverdiyeva, Yavuz Yardim, Zuhre Senturk
Summary: This paper presents the first study on the electrochemical oxidation and electroanalytical determination of anidulafungin (ANF), a semi-synthetic antifungal drug. A boron-doped diamond (BDD) electrode was used in this study, which was pre-treated electrochemically. The study found that ANF exhibited a single and irreversible oxidation step when analyzed using cyclic voltammetry. The electrode process was controlled by a dual mechanism of diffusion and adsorption. Square-wave voltammetry was employed to systematically study the effect of various experimental conditions on the adsorption behavior of ANF. The proposed method showed practical applicability in commercial parenteral dosage forms.
Article
Chemistry, Analytical
Hemn A. H. Barzani, Hoshyar Saadi Ali, Cihat Sahin, Musa Kiran, Yavuz Yardim
Summary: An effective electrochemical sensor using an unmodified boron-doped diamond electrode was developed for determining genistein by square-wave voltammetry. The cyclic voltammetry study showed irreversible behavior and well-defined oxidation peaks, with pH and supporting electrolytes influencing the oxidation process. The method allowed for quantification of genistein in a linear range of concentrations, with low detection limits. The developed method was successfully applied to detect genistein in model human urine samples.
Article
Materials Science, Multidisciplinary
Hoshyar Saadi Ali, Hemn A. H. Barzani, Yavuz Yardim, Zuhre Senturk
Summary: This study presents the first electrochemical investigation of caspofungin using a pretreated boron-doped diamond electrode. By optimizing the experimental conditions, the sensitivity of the voltammetric measurements was improved, allowing for successful determination of caspofungin concentration in commercial dosage formulations.
DIAMOND AND RELATED MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Yavuz Yardim, Hoshyar Saadi Ali, Hemn A. H. Barzani
Summary: In this study, a novel voltammetric approach using an unmodified boron-doped diamond electrode was developed for the quantitative analysis of famciclovir. The method showed good linear response, wide dynamic range, and low detection limit, making it suitable for the analysis of famciclovir in pharmaceutical formulations and serum samples.
DIAMOND AND RELATED MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Hemn A. H. Barzani, Hoshyar Saadi Ali, Hande Izem Ozok, Yavuz Yardim
Summary: The aim of this study was to describe the voltammetric analysis of caffeic acid phenethyl ester (CAPE) using a boron-doped diamond (BDD) electrode in the presence of a cationic surfactant. Cyclic voltammetry was used to determine the oxidation and reduction peaks of CAPE, which showed a well-defined, quasi-reversible behavior. The presence of the cationic surfactant significantly increased the oxidation peak currents of CAPE. The developed approach was successfully applied to detect CAPE concentration in model urine samples.
DIAMOND AND RELATED MATERIALS
(2022)
Article
Environmental Sciences
Cafer Saka, Yavuz Yardim, Omer Sahin, Orhan Baytar
Summary: This study investigates the application of chestnut shell-based activated carbon in iodine adsorption and as an electrochemical double-layer capacitor material. The results show that chestnut shell-based activated carbon exhibits excellent performance in adsorption and capacitor properties.
INTERNATIONAL JOURNAL OF PHYTOREMEDIATION
(2023)
Review
Chemistry, Analytical
Zuhre Senturk
Summary: Voltammetry, a core method in electroanalytical chemistry, has seen significant advances and has become a powerful tool in neuroscience for unraveling the mysteries of the brain in the past century. This review article provides an overview of the 100-year history and fascinating development of voltammetry.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Hemn A. H. Barzani, Hoshyar Saadi Ali, Yavuz Yardim
Summary: This study presents an electroanalytical examination of rifaximin (RFX) using the non-modified boron-doped diamond (BDD) electrode. Cyclic voltammetry (CV) and square-wave (SW) voltammetric techniques were utilized to evaluate RFX. The study showed a linear response in 0.1 M HNO3 solution and a low limit of detection of 0.14 μg mL-1. The developed method was successfully applied to pharmaceutical formulation samples for detecting RFX.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Hemn A. H. Barzani, Yavuz Yardim
Summary: An excellent electrochemical sensor using a non-modified boron-doped diamond electrode was developed for the determination of rifabutin. The oxidation of rifabutin showed irreversible behavior with diffusion-controlled and well-defined two oxidation peaks. The addition of cetyltrimethylammonium bromide greatly enhanced the anodic peak currents of rifabutin, especially under accumulation conditions. This method provided accurate quantification of rifabutin and was successfully used for evaluation in pharmaceutical formulation.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Electrochemistry
Hande Izem Ozok, Musa Kiran, Oruc Yunusoglu, Yavuz Yardim
Summary: In this study, a new electroanalytical approach for sensing umifenovir using an anodically pretreated boron-doped diamond electrode was developed. The oxidation behavior of umifenovir was investigated using cyclic voltammetry and was found to be adsorption-controlled with two oxidation peaks. The second oxidation peak was enhanced by adding sodium dodecyl sulfate (SDS) as a surfactant. Umifenovir was quantified using its second oxidation peak, and the linear relationship between the peak current and concentration allowed for determination of umifenovir in pharmaceutical formulations and urine samples.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Environmental Sciences
Canan Akunal Turel, Oruc Yunusoglu
Summary: The aim of this study was to investigate the protective effects of triterpene oleanolic acid on mice brain tissue with PTZ-induced epileptic seizures. PTZ injection caused significant seizures, but oleanolic acid treatment prolonged seizure onset latency and duration, and decreased seizure scores. Oleanolic acid also increased antioxidant enzyme activity and levels in the brain. These findings suggest that oleanolic acid may have anticonvulsant potential and protect against oxidative stress and cognitive disturbances in PTZ-induced seizures.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Pinar Talay Pinar, Gokhan Uzun, Zuhre Senturk
Summary: This study describes the first electrochemical investigation of ceritinib, a small-molecule tyrosine kinase inhibitor used as a targeted anticancer drug. Cyclic voltammetry was used, and ceritinib showed two pairs of oxidation/reduction peaks in aqueous solution. The electrode process is controlled by a mixed diffusion and adsorption mechanism. Various factors, such as pH, nature of the supporting electrolyte, presence of anionic surfactant, pre-concentration variables, and instrumental parameters, were shown to affect the current response of ceritinib. The developed methodology using square-wave adsorptive stripping voltammetry showed linear calibration curves and low detection limits for the oxidation peaks of ceritinib.
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
(2023)
Article
Pharmacology & Pharmacy
Oruc Yunusoglu
Summary: Nicotine addiction poses a significant burden on global public health and economy. Resveratrol has positive effects on drug addiction and substance addiction, inhibiting the reward properties and reinstatement of nicotine. It could be beneficial as an adjuvant pharmacotherapy for nicotine addiction.
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2023)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)