Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer′s disease

Amyloid beta-mediated KIF5A deficiency disrupts anterograde axonal mitochondrial movement

(2019) Qi Wang et al.   NEUROBIOLOGY OF DISEASE

Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

(2019) Michael F. Egan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chronic ghrelin administration restores hippocampal long-term potentiation and ameliorates memory impairment in rat model of Alzheimer's disease

(2018) Maryam Eslami et al.   HIPPOCAMPUS

MK-0677, a Ghrelin Agonist, Alleviates Amyloid Beta-Related Pathology in 5XFAD Mice, an Animal Model of Alzheimer’s Disease

(2018) Yu-on Jeong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hippocampus ghrelin receptor signaling promotes socially-mediated learned food preference

(2018) Ted M. Hsu et al.   NEUROPHARMACOLOGY

Trial of Solanezumab for Mild Dementia Due to Alzheimer’s Disease

(2018) Lawrence S. Honig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired Hippocampal Neurogenesis and its Enhancement with Ghrelin in 5XFAD Mice

(2018) Minho Moon et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Serum Acylated Ghrelin Levels in Patients with Mild Cognitive Impairment

(2017) Xi Cao et al.   JOURNAL OF ALZHEIMERS DISEASE

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid β (Aβ1-40) administration in mice

(2017) V. V. Santos et al.   JOURNAL OF NEUROENDOCRINOLOGY

Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony

(2017) Stefania Forner et al.   TRENDS IN NEUROSCIENCES

Novel approach for accurate tissue-based protein colocalization and proximity microscopy

(2017) Mirjam I. Lutz et al.   Scientific Reports

The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting

(2017) Bharath K. Mani et al.   Molecular Metabolism

Expression of the Ghrelin and Neurotensin Systems is Altered in the Temporal Lobe of Alzheimer's Disease Patients

(2017) Manuel D. Gahete et al.   JOURNAL OF ALZHEIMERS DISEASE

A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons

(2016) Gemma Navarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial

(2016) Serge Gauthier et al.   LANCET

Locus coeruleus and dopaminergic consolidation of everyday memory

(2016) Tomonori Takeuchi et al.   NATURE

A proposal for validation of antibodies

(2016) Mathias Uhlen et al.   NATURE METHODS

Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease

(2016) Lu Wang et al.   PLoS One

Short-term calorie restriction enhances adult hippocampal neurogenesis and remote fear memory in a Ghsr-dependent manner

(2016) Amanda K.E. Hornsby et al.   PSYCHONEUROENDOCRINOLOGY

Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer’s disease

(2016) Simon J. Beck et al.   Nature Communications

Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X

(2015) V. Muczynski et al.   BLOOD

Hippocampal Dopamine/DRD1 Signaling Dependent on the Ghrelin Receptor

(2015) Andras Kern et al.   CELL

Trends in inpatient antiparkinson drug use in the USA, 2001–2012

(2015) James A. G. Crispo et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Ghrelin agonist does not foster insulin resistance but improves cognition in an Alzheimer’s disease mouse model

(2015) Nicolas Kunath et al.   Scientific Reports

Hippocampus ghrelin signaling mediates appetite through lateral hypothalamic orexin pathways

(2015) Ted M Hsu et al.   eLife

Properties of spontaneous and miniature excitatory postsynaptic currents in neurons of the rat prefrontal cortex

(2015) S. L. Malkin et al.   JOURNAL OF EVOLUTIONARY BIOCHEMISTRY AND PHYSIOLOGY

Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice

(2015) Lin Lu et al.   PLoS One

The Hypothalamus in Alzheimer’s Disease

(2014) Stavros J. Baloyannis et al.   American Journal of Alzheimers Disease and Other Dementias

The Growth Hormone Secretagogue Receptor: Its Intracellular Signaling and Regulation

(2014) Yue Yin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolic Control of Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII)-mediated Caspase-2 Suppression by the B55β/Protein Phosphatase 2A (PP2A)

(2014) Bofu Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroanatomical characterization of a growth hormone secretagogue receptor-green fluorescent protein reporter mouse

(2014) Bharath K. Mani et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Reconsidering hippocampal neurogenesis in Alzheimer's disease

(2014) Alonso Martinez-Canabal   Frontiers in Neuroscience

Apo-Ghrelin Receptor (apo-GHSR1a) Regulates Dopamine Signaling in the Brain

(2014) Andras Kern et al.   Frontiers in Endocrinology

Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease

(2013) Andrea C. Paula-Lima et al.   JOURNAL OF NEUROCHEMISTRY

Neuron loss in the 5XFAD mouse model of Alzheimer’s disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activation

(2013) William A Eimer et al.   Molecular Neurodegeneration

Hunger in the Absence of Caloric Restriction Improves Cognition and Attenuates Alzheimer's Disease Pathology in a Mouse Model

(2013) Emily J. Dhurandhar et al.   PLoS One

Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus

(2013) L. F. Ribeiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypothalamic control of energy balance: insights into the role of synaptic plasticity

(2013) Marcelo O. Dietrich et al.   TRENDS IN NEUROSCIENCES

Animal Models of Alzheimer Disease

(2013) F. M. LaFerla et al.   Cold Spring Harbor Perspectives in Medicine

Ghrelin Signaling in the Ventral Hippocampus Stimulates Learned and Motivational Aspects of Feeding via PI3K-Akt Signaling

(2012) Scott E. Kanoski et al.   BIOLOGICAL PSYCHIATRY

Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

(2011) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRI

(2010) G. A. Kerchner et al.   NEUROLOGY

Coactivation of G Protein Signaling by Cell-Surface Receptors and an Intracellular Exchange Factor

(2008) Michael J. Lee et al.   CURRENT BIOLOGY

Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling

(2008) Jean-Pierre Vilardaga et al.   Nature Chemical Biology

Growth hormone secretagogue MK-677: No clinical effect on AD progression in a randomized trial

(2008) J. J. Sevigny et al.   NEUROLOGY