Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C

Anemia of inflammation

(2018) Guenter Weiss et al.   BLOOD

Monocyte-derived macrophages expand the murine stress erythropoietic niche during the recovery from anemia

(2018) Chang Liao et al.   BLOOD

NF-κB regulates GDF-15 to suppress macrophage surveillance during early tumor development

(2017) Nivedita M. Ratnam et al.   JOURNAL OF CLINICAL INVESTIGATION

Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal

(2016) Eric M. Pietras et al.   NATURE CELL BIOLOGY

Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells

(2016) Zhen Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro culture of stress erythroid progenitors identifies distinct progenitor populations and analogous human progenitors

(2015) J. Xiang et al.   BLOOD

Anemia: progress in molecular mechanisms and therapies

(2015) Vijay G Sankaran et al.   NATURE MEDICINE

Macrophages eat cancer cells using their own calreticulin as a guide: Roles of TLR and Btk

(2015) Mingye Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages

(2014) Malay Haldar et al.   CELL

A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin

(2013) A. Kim et al.   BLOOD

Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus

(2013) S. Gardenghi et al.   BLOOD

Regulation of erythropoiesis by hypoxia-inducible factors

(2013) Volker H. Haase   BLOOD REVIEWS

Anemia in the ICU

(2012) Devina Prakash   CRITICAL CARE CLINICS

Increased Susceptibility to Salmonella Infection in Signal Regulatory Protein  -Deficient Mice

(2012) L.-X. Li et al.   JOURNAL OF IMMUNOLOGY

Chronic IFN-  production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis

(2011) S. F. Libregts et al.   BLOOD

Erythropoietin Contrastingly Affects Bacterial Infection and Experimental Colitis by Inhibiting Nuclear Factor-κB-Inducible Immune Pathways

(2011) Manfred Nairz et al.   IMMUNITY

Clinical relevance and treatment of nonautoimmune anemia in chronic lymphocytic leukemia

(2011) Molica et al.   Cancer Management and Research

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

(2010) B. J. Sasu et al.   BLOOD

Erythropoietin stimulates spleen BMP4-dependent stress erythropoiesis and partially corrects anemia in a mouse model of generalized inflammation

(2010) S. Millot et al.   BLOOD

Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors

(2010) Omid F. Harandi et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate Immune Activation during Salmonella Infection Initiates Extramedullary Erythropoiesis and Splenomegaly

(2010) A. Jackson et al.   JOURNAL OF IMMUNOLOGY

Induction of an IL7-R+c-Kithi myelolymphoid progenitor critically dependent on IFN-γ signaling during acute malaria

(2010) Nikolai N Belyaev et al.   NATURE IMMUNOLOGY

Hypoxia Regulates BMP4 Expression in the Murine Spleen during the Recovery from Acute Anemia

(2010) Dai-Chen Wu et al.   PLoS One

Disease-Related Anemia in Chronic Lymphocytic Leukemia Is Not Due to Intrinsic Defects of Erythroid Precursors: A Possible Pathogenetic Role for Tumor Necrosis Factor-Alpha

(2009) Olga A. Tsopra et al.   ACTA HAEMATOLOGICA

Maintenance of the BMP4-dependent stress erythropoiesis pathway in the murine spleen requires hedgehog signaling

(2008) J. M. Perry et al.   BLOOD

Wave expansion of CD34+ progenitor cells in the spleen in rodent malaria

(2008) Felipe Pessoa de Melo Hermida et al.   EXPERIMENTAL PARASITOLOGY

Role for Spi-C in the development of red pulp macrophages and splenic iron homeostasis

(2008) Masako Kohyama et al.   NATURE