The NMDA receptor activation by d-serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle

The plastic d -serine signaling pathway: Sliding from neurons to glia and vice-versa

(2018) Andrei D. Ivanov et al.   NEUROSCIENCE LETTERS

ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment

(2018) Eitan Kaplan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced astrocytic d-serine underlies synaptic damage after traumatic brain injury

(2017) Enmanuel J. Perez et al.   JOURNAL OF CLINICAL INVESTIGATION

Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses

(2017) Joana S Ferreira et al.   eLife

Glycine release from astrocytes via functional reversal of GlyT1

(2016) Koji Shibasaki et al.   JOURNAL OF NEUROCHEMISTRY

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers

(2016) Edouard Mullarky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rise and Fall of the d -Serine-Mediated Gliotransmission Hypothesis

(2016) Herman Wolosker et al.   TRENDS IN NEUROSCIENCES

D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability

(2016) Hong Lin et al.   Frontiers in Cellular Neuroscience

The alanine-serine-cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission

(2015) H. Safory et al.   EMBO REPORTS

The serine shuttle between glia and neurons: implications for neurotransmission and neurodegeneration: Figure 1

(2015) Herman Wolosker et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

d-Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain

(2014) Darrick T. Balu et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Identity of the NMDA receptor coagonist is synapse specific and developmentally regulated in the hippocampus

(2014) Matildé Le Bail et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP binding to human serine racemase is cooperative and modulated by glycine

(2013) Marialaura Marchetti et al.   FEBS Journal

Neuronal D-Serine and Glycine Release Via the Asc-1 Transporter Regulates NMDA Receptor-Dependent Synaptic Activity

(2013) D. Rosenberg et al.   JOURNAL OF NEUROSCIENCE

D-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase

(2013) J. T. Ehmsen et al.   JOURNAL OF NEUROSCIENCE

Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level

(2013) Yan Li et al.   Nature Communications

Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons

(2012) Michael A. Benneyworth et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Brain-specificPhgdhDeletion Reveals a Pivotal Role for l-Serine Biosynthesis in Controlling the Level of d-Serine, anN-methyl-d-aspartate Receptor Co-agonist, in Adult Brain

(2010) Jung Hoon Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serine racemase is predominantly localized in neurons in mouse brain

(2008) Kazushi Miya et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior

(2008) A C Basu et al.   MOLECULAR PSYCHIATRY