期刊
PLOS ONE
卷 14, 期 8, 页码 -出版社
PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0220547
关键词
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资金
- NSF NeuroNex Award [DBI-1707398]
- Gatsby Charitable Foundation [GAT3419]
- Simons Collaboration for the Global Brain [542939SPI]
- Swartz Foundation
The construction of biologically plausible models of neural circuits is crucial for understanding the computational properties of the nervous system. Constructing functional networks composed of separate excitatory and inhibitory neurons obeying Dale's law presents a number of challenges. We show how a target-based approach, when combined with a fast online constrained optimization technique, is capable of building functional models of rate and spiking recurrent neural networks in which excitation and inhibition are balanced. Balanced networks can be trained to produce complicated temporal patterns and to solve input-output tasks while retaining biologically desirable features such as Dale's law and response variability.
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