Review
Oncology
Abdul Arif Khan
Summary: Colorectal cancer originates from polyps, and research has identified key targets and pathways associated with the transformation of polyps into cancer. Functional overrepresentation analysis has provided insights into the overall mechanism.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Giorgio Grillo, Silvia Tabasso, Roberto Solarino, Giancarlo Cravotto, Clarissa Toson, Elena Ghedini, Federica Menegazzo, Michela Signoretto
Summary: The use of microwave and ultrasound-assisted extraction from algae, especially brown, green, and red algae, shows potential in developing cosmetics with high phenolic content and antioxidant activity. Green algae, particularly Ulva lactuca, stand out as a suitable source of antioxidants for cosmetic formulations. The gel and emulsion formulations made from these extracts are stable and show efficient controlled release of active ingredients.
Article
Mathematics, Applied
Francesca Bertacchini, Pietro S. S. Pantano, Eleonora Bilotta
Summary: This article presents an intellectual journey that started with the discovery of strange attractors in Chua's circuit and led to the production of jewelry through 3D printing. It discusses the chaotic design process used for creating the jewelry and explores the feasibility of incorporating chaos theory into high school STEAM courses. The authors believe that transforming science into art forms can help students acquire scientific knowledge and skills.
Review
Cell Biology
Magdalena Richter, Oliwia Piwocka, Marika Musielak, Igor Piotrowski, Wiktoria M. Suchorska, Tomasz Trzeciak
Summary: Primary cancer cell lines are cell cultures derived from resected tissues and used in oncology research. Techniques for isolation and characterisation involve enzymatic, chemical, or mechanical methods. These cell lines contribute to the development of anti-cancer treatments and drug discovery.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Yawei Wang, Puying Zhao, Ying Zhou, Xiaomin Hu, Hairong Xiong
Summary: Protein hydrolysates are easily digested and utilized, and less likely to cause allergies. Microbial aminopeptidases remove hydrophobic amino acids, improving taste and facilitating production. This process has attracted significant attention from industry and laboratories.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2023)
Review
Chemistry, Physical
Hileia K. S. Souza, Wala Kraiem, Amine Ben Yahia, Adel Aschi, Loic Hilliou
Summary: Hybrid carrageenans, also known as kappa-2 (K2) or weak kappa, are sulfated polysaccharides extracted from specific species of red seaweeds. They have thermo-reversible gelling properties and are gaining interest in industry due to their intermediate texturizing properties. However, further research is needed to fully understand their chemical structure and how it affects their gel formation and rheological properties.
Article
Biochemical Research Methods
Dmitry Meleshko, Iman Hajirasouliha, Anton Korobeynikov
Summary: The development of coronaSPAdes has significantly improved the recovery of full-length RNA viral genomes, outperforming existing SPAdes modes and other popular short-read metagenome and viral assemblers. Leveraging knowledge about viral genome structures, coronaSPAdes extends ideas initially implemented in biosyntheticSPAdes.
Article
Food Science & Technology
Sylvain Delplanque, David Sander
Summary: Inferring emotions based on accessible signals may not be reliable. It is more efficient to use measures to test hypotheses concerning emotions. To avoid reverse inference issues, it is beneficial to leverage converging evidence across the five components of emotions and invest more in methodological developments.
FOOD QUALITY AND PREFERENCE
(2021)
Article
Chemistry, Inorganic & Nuclear
Kei Oota, Ren-Hua Jin
Summary: Chiroptical crystalline complexes of PEI/Tart (P/T) were used as chiral catalytic templates for the preparation of chiral titania (TiO2) and chiral titania/silica (TiO2/SiO2) hybrid. Different enantiomer ratios of P/T systems exhibited varying activity in the chiral transformation to the resulting minerals. P/T complexes with ee only by ±4% showed excellent catalytic templates to generate chiroptical titania and titania/silica. The mechanism of the chiral transformation from enantiomeric excess of P/T to minerals was proposed.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Medicinal
Arindam Talukdar, Ayan Mukherjee, Debomita Bhattacharya
Summary: The abnormal expression of protein methyltransferase (PMT) is related to various diseases, and the focus of current research is on the evolution from nucleoside inhibitors to selective competitive non-nucleoside inhibitors to solve the inherent problems of nucleoside analogues.
JOURNAL OF MEDICINAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Catalina Sandoval-Altamirano, Eduardo Berrios, Javier Morales, Christian Silva, German Gunther
Summary: Phenalenone and its derivatives have high singlet oxygen generation capacity through photosensitization. Efforts have been made to obtain phenalenones with red-shifted absorption while maintaining the ability to generate singlet oxygen. The presence of a dimethylamino substituent at positions 3 or 6 allows for modulation of singlet oxygen generation capacity and fluorescence. Both compounds show red-shifted absorption compared to phenalenone, with different solvent effects on their absorption and emission properties.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Review
Biochemistry & Molecular Biology
Manisha Banerjee, Dhiman Chakravarty, Prakash Kalwani, Anand Ballal
Summary: This review describes the impact of selenium on diverse biological systems, emphasizing its chemical advantages. It discusses the uneven distribution of selenium and how it affects bioavailability and habitat. The review also explores the antioxidant functions of selenium and its deleterious effects depending on its chemical form. Additionally, it highlights the potential therapeutic use of selenium's pro-oxidant nature and its ability to offset the toxic effects of mercury. Finally, the review suggests avenues for future research in selenium biology.
JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY
(2022)
Article
Oncology
Rosemary J. Akhurst
Summary: Epithelial-to-mesenchymal transition (EMT) is a cell shape-changing process that plays a critical role in embryogenesis and disease progression. It is influenced by extracellular factors and intracellular signaling pathways. EMT is associated with tumor progression, development of a stem-like cell state, and drug resistance.
SEMINARS IN CANCER BIOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Gourvi Kumari, Kumar Abhishek, Sneha Singh, Afzal Hussain, Mohammad A. Altamimi, Harishkumar Madhyastha, Thomas J. Webster, Abhimanyu Dev
Summary: The transition from 3D to 4D printing has revolutionized various domains, adding a time-dependent response. This review discusses the significance, demands, smart materials/biomaterials, bioinks, and printers used in 4DP technology. It also explores the limitations and challenges in bioprinting processes and bioinks. The future potential of 4D printing is briefly discussed.
Review
Biotechnology & Applied Microbiology
Gourvi Kumari, Kumar Abhishek, Sneha Singh, Afzal Hussain, Mohammad A. Altamimi, Harishkumar Madhyastha, Thomas J. Webster, Abhimanyu Dev
Summary: Recent advancements in biomedical tissue engineering, specifically 4D printing and bioprinting, have opened new possibilities for tissue regeneration, organ regeneration, and early diagnosis of deadly diseases. This review primarily focuses on the clinical applications of these technologies for early disease detection and drug delivery.
