期刊
ORGANIC LETTERS
卷 21, 期 18, 页码 7498-7503出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.9b02788
关键词
-
资金
- 1000-Youth Talents Plan
- National Natural Science Foundation of China [21702149]
- Wuhan University
- Fundamental Research Funds for the Central Universities [204201810012]
An easy-to-handle Ni-catalyzed three-component reductive arylacylation of alkenes using isobutyl chloroformate as a CO source was described. This reaction operates under mild reaction conditions without the need to use toxic CO gas or metal carbonyl reagents. In addition, this method allows for rapid synthesis of 3,3-disubstituted oxindoles with an all-carbon quaternary stereocenter containing a ketone group in good yields with broad substrate scope.
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