Article
Economics
Gang Jin, Binbin Yu, Kunrong Shen
Summary: Boosting domestic trade and increasing energy productivity are main objectives in China's new normal economic development. The study finds an inverted U-shaped effect of domestic trade on the growth of energy total factor productivity (TFP), supporting the strategy proposed by the Chinese government to build a new development pattern with a large domestic cycle as its mainstay and in which a dual domestic and international cycle would be mutually promoting.
Article
Business
Yaozhi Zhang
Summary: This study challenges the conventional wisdom by examining the potential curvilinear effects of tourist co-creation on tourism marketing outcomes. The findings reveal an inverted U-shaped relationship between the degree of tourist co-creation and various tourism marketing performance indicators. Additionally, the study highlights the positive moderating role of tourist experiential fluency in this relationship, providing practical measures to mitigate the negative impacts of excessive tourist co-creation on tourism marketing outputs.
JOURNAL OF BUSINESS RESEARCH
(2023)
Article
Urban Studies
Shangguang Yang, Danyang Wang, Kevin Lo
Summary: The cross-sectional study illustrates an inverted-U relationship between housing prices and migrant integration, where migrant integration initially rises with increasing housing prices, but then decreases after reaching a turning point.Various robustness and variation tests have confirmed the reliability of this inverted U relationship.
Article
Psychology, Multidisciplinary
Hualong Yang, Dan Li
Summary: The study found an inverted-U relationship between achievement level and health management performance, with social network size and health condition negatively moderating this relationship.
COMPUTERS IN HUMAN BEHAVIOR
(2021)
Article
Business
Niek Althuizen
Summary: A common assumption in the psychology of aesthetics is the inverted U-shape relationship between complexity and liking, but studies in the context of product design have found limited evidence to support this. Factors such as arousal or interest and perceived producer effort or skill were found to be more important mediators than cognitive effort.
PSYCHOLOGY & MARKETING
(2021)
Article
Biochemistry & Molecular Biology
Adrian P. Mundt, Enzo Rozas Serri, Matias Irarrazaval, Richard O'Reilly, Stephen Allison, Tarun Bastiampillai, Seggane Musisi, Ashraf Kagee, Andrei Golenkov, Joseph El-Khoury, Seon-Cheol Park, Lydia Chwastiak, Stefan Priebe
Summary: The present study is the first expert consensus on minimum and optimal psychiatric bed numbers. The study used the Delphi method and included experts from both high-income countries and low- and middle-income countries. The findings suggest that many low- and middle-income countries have inadequate numbers of psychiatric beds.
MOLECULAR PSYCHIATRY
(2022)
Article
Education & Educational Research
Wondwesen Tafesse
Summary: This study examines the relationship between social networking sites use and college students' academic performance and finds an inverted U-shaped relationship. Moderate use of social networking sites is positively associated with academic performance, but excessive use has a negative impact.
INTERNATIONAL JOURNAL OF EDUCATIONAL TECHNOLOGY IN HIGHER EDUCATION
(2022)
Article
Multidisciplinary Sciences
Gaofeng Wang, Yetong Gan, Haodong Yang
Summary: This study explores the relationship between knowledge diversity of collaborating team members and research performance. It finds that the relationship between interdisciplinary collaboration diversity and societal impact follows an inverted U-shaped pattern, rather than a simple linear one. Additionally, as the number of collaborative disciplines increases, the negative influences start to outweigh the benefits, indicating that diversity does not always lead to positive impacts.
SCIENTIFIC REPORTS
(2022)
Article
Management
Ying Ying, Xingchen Meng
Summary: Digital transformation is an increasingly critical issue in the digital era. This paper expands research on the drivers of corporate digital transformation and examines executive contextual factors. Using text mining and a nonlinear model, the study analyzes the impact of returnee executives on corporate digital transformation in Chinese A-share listed companies from 2012 to 2021. The findings show an inverted U-shaped, nonlinear relationship between returnee executives and company digital transformation, with financial restrictions strengthening this association and financial position weakening it.
TECHNOLOGY ANALYSIS & STRATEGIC MANAGEMENT
(2023)
Review
Biochemistry & Molecular Biology
Monika A. Waszczuk, Katherine G. Jonas, Marina Bornovalova, Gerome Breen, Cynthia M. Bulik, Anna R. Docherty, Thalia C. Eley, John M. Hettema, Roman Kotov, Robert F. Krueger, Todd Lencz, James J. Li, Evangelos Vassos, Irwin D. Waldman
Summary: Genome-wide association studies (GWAS) have the potential to provide biological insights into disease mechanisms and offer clinically useful biomarkers. This review examines the use of quantitative and transdiagnostic phenotypes in GWAS for major psychiatric disorders. The authors discuss themes and recommendations, including issues of sample size, phenotypic reliability, sources of phenotypic information, and the use of biological and behavioral markers. The review also highlights the importance of multi-trait methods and the potential of dimensional and transdiagnostic phenotypes for gene discovery in psychiatric conditions.
MOLECULAR PSYCHIATRY
(2023)
Review
Business
Jungwon Lee, Cheol Park
Summary: Moderated by interactive and motivational factors, review variance exhibits an inverse-U-shaped relationship with review variance. Specifically, as an interaction factor, review valence and owned social media (OSM) resulted in positive interaction effects, and as a motivation factor, the number of alternatives exhibited a positive interaction effect with review variance. The effect of review variance was less pronounced in the USA than in Korea.
Article
Oncology
Ian J. Cooke, Dattatraya Patil, Katherine Bobrek, Vikram Narayan, Viraj Master, Mark Rapaport, Christopher P. Filson, Shreyas S. Joshi
Summary: A new diagnosis of bladder cancer was found to be associated with a higher risk of developing depression and anxiety compared with matched controls, with women and patients receiving more radical treatments showing higher rates of significant depression and anxiety.
Article
Public, Environmental & Occupational Health
Changli Jia, Yanwen Long, Xiaoxia Luo, Xiao Li, Wenjing Zuo, Yibo Wu
Summary: This study used nationwide data collected in 2021 to explore the relationship between education and family health in China's urban-rural dual society. The findings revealed disparities in various factors between urban and rural areas, and an inverted U-shaped relationship between education and family health. Highly-educated individuals experienced diminishing returns in health, mediated by work-family conflict. The study also highlighted the significant contribution of education to the urban-rural gap in family health.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Business
Shaobo Wei, Shibin Sheng
Summary: This study investigates the influence of geographic distance between a supplier and its customers on supplier innovation and how this effect is further moderated by customer concentration and the institutional development of the supplier's region. The test of the proposed conceptual model using secondary data from Chinese publicly listed manufacturing firms during 2008-2014 reveals an inverted U-shaped relationship between geographic distance and supplier innovation, which is weakened by customer concentration but strengthened by institutional development.
INDUSTRIAL MARKETING MANAGEMENT
(2023)
Article
Ecology
Gozal Ahmadova, Blanca L. Delgado-Marquez, Luis E. Pedauga, Dante Leyva-de la Hiz
Summary: Digitalization has both positive and negative effects on environmental performance, with the level of a country's institutional framework moderating this relationship.
ECOLOGICAL ECONOMICS
(2022)
Article
Clinical Neurology
Shankar Tumati, Jan-Bernard C. Marsman, Peter Paul De Deyn, Sander Martens, Andre Aleman
JOURNAL OF AFFECTIVE DISORDERS
(2020)
Article
Biochemistry & Molecular Biology
Jianfeng Zhang, Zirui Huang, Shankar Tumati, Georg Northoff
Article
Neuroimaging
Tania M. Setiadi, Sander Martens, Esther M. Opmeer, Jan-Bernard C. Marsman, Shankar Tumati, Fransje E. Reesink, Peter P. De Deyn, Andre Aleman, Branislava Curcic-Blake
Summary: Apathy in amnestic Mild Cognitive Impairment is associated with lower FA in various white matter pathways, suggesting a relationship between the severity of apathy and white matter integrity.
NEUROIMAGE-CLINICAL
(2021)
Review
Biochemistry & Molecular Biology
Shankar Tumati, Martin P. Paulus, Georg Northoff
Summary: Imaging studies in anxiety disorders reveal abnormal functional connectivity in the salience network, somatomotor network, and default mode network. These network changes may be due to reduced phase synchronization between neural and cardiac activity, influenced by cardiac afferents reaching subcortical serotonergic and noradrenergic nuclei, impacting emotional arousal and sense-of-self in anxiety disorders. Integrating theories of active interference and hyperarousal, a neuro-cardiac and biochemically-driven mechanism is proposed for key psychopathological symptoms in anxiety disorders.
MOLECULAR PSYCHIATRY
(2021)
Article
Biology
Mehrshad Golesorkhi, Javier Gomez-Pilar, Shankar Tumati, Maia Fraser, Georg Northoff
Summary: Golesorkhi et al. investigate intrinsic neural timescales during resting and task states using a combination of magnetoencephalography data, machine learning, and simulation. They provide insights into how the temporal hierarchy of the human cortex intersects with its spatial core-periphery hierarchy.
COMMUNICATIONS BIOLOGY
(2021)
Article
Neurosciences
Annemarie Wolff, Liang Chen, Shankar Tumati, Mehrshad Golesorkhi, Javier Gomez-Pilar, Jie Hu, Shize Jiang, Ying Mao, Andre Longtin, Georg Northoff
Summary: The study found that neural variability tends to decrease after a stimulus is presented, and the dynamics of the prestimulus period can influence this reduction in variability. Additionally, the impact of the stimulus on neural activity is shown to be greater in the later poststimulus period compared to the early poststimulus period.
Article
Neurosciences
Mehrshad Golesorkhi, Javier Gomez-Pilar, Yasir Catal, Shankar Tumati, Mustapha C. E. Yagoub, Emanuel A. Stamatakis, Georg Northoff
Summary: Using functional magnetic resonance imaging data, this study investigates the topographical hierarchy and temporal dynamics of lower- and higher-order networks in the brain. The results show differences in complexity and frequency distribution between these networks at rest, as well as task-related changes. Additionally, there is a hierarchical and causal relationship between frequency distribution and complexity, with the rest state acting as a mediator. These findings highlight the importance of neural dynamics at rest in shaping complexity during task states.
Article
Geriatrics & Gerontology
Shankar Tumati, Krista L. Lanctot, RuoDing Wang, Abby Li, Andrew Davis, Nathan Herrmann
Summary: This retrospective study found that medical cannabis is more often used by older women, with pain relief being the primary indication and CBD-containing cannabis oils being the most common type used. Follow-up data showed improvements in pain, sleep, and mood symptoms among older adults after cannabis use. More research is needed to determine proper indications, doses of active ingredients, and outcomes in the older adult population.
Review
Biochemistry & Molecular Biology
Shankar Tumati, Nathan Herrmann, Giovanni Marotta, Abby Li, Krista L. Lanctot
Summary: Agitation is a common symptom in Alzheimer's disease (AD), and its treatment is urgently needed. Recent research on blood-based biomarkers of agitation in AD has provided new insights into its mechanisms and potential treatments. Inflammatory biomarkers are increased in patients with agitation and may predict the development and severity of agitation. Other biomarkers associated with agitation include markers of oxidative stress, brain cholesterol metabolism, and motor activity. These biomarkers have the potential to predict and monitor treatment response in interventional studies for agitation.
NEUROCHEMISTRY INTERNATIONAL
(2022)
Article
Geriatrics & Gerontology
Nena Lejko, Shankar Tumati, Esther M. Opmeer, Jan-Bernard C. Marsman, Fransje E. Reesink, Peter P. De Deyn, Andre Aleman, Branislava Curcic-Blake
Summary: The impaired planning ability in individuals with amnestic mild cognitive impairment (aMCI) is associated with lower activation in a diffuse cortico-thalamic network. Higher planning-related activity is related to better memory performance.
EXPERIMENTAL GERONTOLOGY
(2022)
Article
Neurosciences
Vivian Feng, Shankar Tumati, Ruoding Wang, Kritleen K. Bawa, Damien Gallagher, Nathan Herrmann, Susan Marzolini, Paul Oh, Ana Andreazza, Krista L. Lanctot
Summary: This study found that markers of late-stage lipid peroxidation are elevated in coronary artery disease patients with poor sleep and are associated with daily disturbances. However, this association is not related to other factors or with sleep quality and its factors after exercise intervention.
Article
Geriatrics & Gerontology
Vivian Feng, Krista Lanctot, Nathan Herrmann, Alex Kiss, Corinne E. Fischer, Alastair J. Flint, Linda Mah, Benoit H. Mulsant, Bruce G. Pollock, Tarek K. Rajji, Shankar Tumati, Nicolaas Paul Verhoeff, Ariel Graff-Guerrero, Damien Gallagher
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Article
Geriatrics & Gerontology
Krista L. Lanctot, Luc Rivet, Shankar Tumati, Jamie Perin, Krushnaa Sankhe, Danielle Vieira, Jacobo Mintzer, Paul B. Rosenberg, David Shade, Alan J. Lerner, Prasad R. Padala, Olga Brawman-Mintzer, Christopher H. van Dyck, Anton P. Porsteinsson, Suzanne Craft, Allan I. Levey, Kalpana P. Padala, Nathan Herrmann
Summary: The study found that younger patients, those prescribed cholinesterase inhibitors, with optimal diastolic blood pressure, and without anxiety or agitation were more likely to benefit from treatment with methylphenidate for apathy in Alzheimer's disease.
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
(2023)
Review
Behavioral Sciences
Grace K. Y. Koo, Amish Gaur, Shankar Tumati, Raphael W. Kusumo, Kritleen K. Bawa, Nathan Herrmann, Damien Gallagher, Krista L. Lancto
Summary: Anodal transcranial direct current stimulation (tDCS) can improve cognition in healthy older adults, those with Alzheimer's disease (AD) and mild cognitive impairment (MCI), albeit with considerable variability in response. This systematic review identifies interindividual factors that may influence tDCS outcomes in older individuals with or without cognitive impairment. Factors such as lower baseline cognitive function, preserved brain structure, better baseline functional connectivity, genetic polymorphisms, and concomitant medication use may predict better tDCS outcomes, but further research is needed. Age, cognitive reserve, sex, and AD risk factors did not consistently affect tDCS outcomes. Considering individual differences in baseline cognition, particularly in combined interventions, may maximize the therapeutic potential of tDCS.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Oncology
Diana C. Ghinda, Yufei Yang, Shuai Wu, Junfeng Lu, Lan Su, Stefano Damiani, Shankar Tumati, Gerard Jansen, Hugues Duffau, Jin-Song Wu, Georg Northoff
JCO PRECISION ONCOLOGY
(2020)
Article
Behavioral Sciences
Edna C. Cieslik, Markus Ullsperger, Martin Gell, Simon B. Eickhoff, Robert Langner
Summary: Previous studies on error processing have primarily focused on the posterior medial frontal cortex, but the role of other brain regions has been underestimated. This study used activation likelihood estimation meta-analyses to explore brain activity related to committing errors and responding successfully in interference tasks. It was found that the salience network and the temporoparietal junction were commonly involved in both correct and incorrect responses, indicating their general involvement in coping with situations that require increased cognitive control. Error-specific convergence was observed in the dorsal posterior cingulate cortex, posterior thalamus, and left superior frontal gyrus, while successful responding showed stronger convergence in the dorsal attention network and lateral prefrontal regions. Underrecruitment of these regions in error trials may reflect failures in activating the appropriate stimulus-response contingencies necessary for successful response execution.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2024)