Translating the gut microbiome: ready for the clinic?

Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle

(2019) Edoardo Pasolli et al.   CELL

Long-term Outcomes after Fecal Microbiota Transplant in Cirrhosis

(2019) Jasmohan S. Bajaj et al.   GASTROENTEROLOGY

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

(2019) Nobuhiro Nakamoto et al.   Nature Microbiology

Gut mucosal virome alterations in ulcerative colitis

(2019) Tao Zuo et al.   GUT

Efficacy of Fecal Microbiota Transplantation in Irritable Bowel Syndrome

(2019) Dabo Xu et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Gut Microbiota in Causation, Detection, and Treatment of Cancer

(2019) Clodagh L. Murphy et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Longitudinal multi-omics of host–microbe dynamics in prediabetes

(2019) Wenyu Zhou et al.   NATURE

Racioethnic diversity in the dynamics of the vaginal microbiome during pregnancy

(2019) Myrna G. Serrano et al.   NATURE MEDICINE

Responsible stewardship for communicating microbiome research to the press and public

(2019) Yue Shan et al.   NATURE MEDICINE

The ancestral and industrialized gut microbiota and implications for human health

(2019) Erica D. Sonnenburg et al.   NATURE REVIEWS MICROBIOLOGY

Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance

(2019) Sophia R. Levan et al.   Nature Microbiology

The circulating microbiome signature and inferred functional metagenomics in alcoholic hepatitis

(2018) Puneet Puri et al.   HEPATOLOGY

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Translocation of a gut pathobiont drives autoimmunity in mice and humans

(2018) S. Manfredo Vieira et al.   SCIENCE

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

(2018) Jotham Suez et al.   CELL

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

(2018) Niv Zmora et al.   CELL

Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography

(2018) Mélanie Deschasaux et al.   NATURE MEDICINE

Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection

(2018) Tao Zuo et al.   Nature Communications

Clinical Application and Potential of Fecal Microbiota Transplantation

(2018) R.E. Ooijevaar et al.   Annual Review of Medicine

US Immigration Westernizes the Human Gut Microbiome

(2018) Pajau Vangay et al.   CELL

Bacteria engineered to produce IL-22 in intestine induce expression of REG3G to reduce ethanol-induced liver disease in mice

(2018) Tim Hendrikx et al.   GUT

Multicenter Trial of a Combination Probiotic for Children with Gastroenteritis

(2018) Stephen B. Freedman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children

(2018) David Schnadower et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recovery of gut microbiota of healthy adults following antibiotic exposure

(2018) Albert Palleja et al.   Nature Microbiology

Feeding the microbiota: transducer of nutrient signals for the host

(2017) Fergus Shanahan et al.   GUT

Recovery of ethanol-inducedAkkermansia muciniphiladepletion ameliorates alcoholic liver disease

(2017) Christoph Grander et al.   GUT

Faecal Microbiota Transplantation for Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

(2017) Sudarshan Paramsothy et al.   Journal of Crohns & Colitis

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

(2017) V. Gopalakrishnan et al.   SCIENCE

Analysis ofFusobacteriumpersistence and antibiotic response in colorectal cancer

(2017) Susan Bullman et al.   SCIENCE

Meta-analysis of gut microbiome studies identifies disease-specific and shared responses

(2017) Claire Duvallet et al.   Nature Communications

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

(2016) Martin Kummen et al.   GUT

Management of the critically ill patient with cirrhosis: A multidisciplinary perspective

(2016) Mitra K. Nadim et al.   JOURNAL OF HEPATOLOGY

Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation

(2016) Hilary P. Browne et al.   NATURE

Diet-induced extinctions in the gut microbiota compound over generations

(2016) Erica D. Sonnenburg et al.   NATURE

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

Antibiotic resistance is the quintessential One Health issue

(2016) T. P. Robinson et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

The healthy human microbiome

(2016) Jason Lloyd-Price et al.   Genome Medicine

The FAIR Guiding Principles for scientific data management and stewardship

(2016) Mark D. Wilkinson et al.   Scientific Data

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease

(2015) Jason M. Norman et al.   CELL

Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

(2015) Benoit Chassaing et al.   NATURE

Small molecules from the human microbiota

(2015) M. S. Donia et al.   SCIENCE

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

An integrated catalog of reference genes in the human gut microbiome

(2014) Junhua Li et al.   NATURE BIOTECHNOLOGY

Diet rapidly and reproducibly alters the human gut microbiome

(2013) Lawrence A. David et al.   NATURE

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

The gut microbiota—a clinical perspective on lessons learned

(2012) Fergus Shanahan   Nature Reviews Gastroenterology & Hepatology

Extensive personal human gut microbiota culture collections characterized and manipulated in gnotobiotic mice

(2011) A. L. Goodman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA