Whole-genome sequencing of triple-negative breast cancers in a population-based clinical study

Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative

(2018) L. Rydén et al.   BRITISH JOURNAL OF SURGERY

Targeting the replication stress response in cancer

(2018) Josep V. Forment et al.   PHARMACOLOGY & THERAPEUTICS

A Dominantly Inherited 5′ UTR Variant Causing Methylation-Associated Silencing of BRCA1 as a Cause of Breast and Ovarian Cancer

(2018) D.Gareth R. Evans et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic Rearrangement Signatures and Clinical Outcomes in High-Grade Serous Ovarian Cancer

(2017) R Tyler Hillman et al.   JNCI-Journal of the National Cancer Institute

A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers

(2017) Dominik Glodzik et al.   NATURE GENETICS

A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer

(2017) Paz Polak et al.   NATURE GENETICS

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

(2017) Helen Davies et al.   NATURE MEDICINE

Identification of pathogenic retrotransposon insertions in cancer predisposition genes

(2017) Yaping Qian et al.   Cancer Genetics

Genomic Rearrangement Signatures and Clinical Outcomes in High-Grade Serous Ovarian Cancer

(2017) R Tyler Hillman et al.   JNCI-Journal of the National Cancer Institute

Ovarian Cancers Harboring Inactivating Mutations inCDK12Display a Distinct Genomic Instability Pattern Characterized by Large Tandem Duplications

(2016) Tatiana Popova et al.   CANCER RESEARCH

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer

(2016) M. L. Telli et al.   CLINICAL CANCER RESEARCH

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

(2016) Serena Nik-Zainal et al.   NATURE

Biology and Management of Patients With Triple-Negative Breast Cancer

(2016) P. Sharma   ONCOLOGIST

The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine

(2015) Lao H Saal et al.   Genome Medicine

DNA replication stress: Causes, resolution and disease

(2014) Abdelghani Mazouzi et al.   EXPERIMENTAL CELL RESEARCH

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

(2013) J-Y Park et al.   ONCOGENE

Mutational Processes Molding the Genomes of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

A refined molecular taxonomy of breast cancer

(2011) M Guedj et al.   ONCOGENE

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

Accurate whole human genome sequencing using reversible terminator chemistry

(2008) David R. Bentley et al.   NATURE

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE